Resident and infiltrating cells in the rat iris during the early stages of experimental melanin protein-induced uveitis (EMIU)

Ocular Immunology and Inflammation

Volumn 5, Issue 4, 1997, Pages 223-234

  McMenamin, Paul G ^a   Crewe, Julie ^a   Kijlstra, Aize ^b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

Immunohistochemistry; Inflammation; Iris; Melanin; Uveitis

Indexed keywords

FREUND ADJUVANT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MELANIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; IMMUNOHISTOCHEMISTRY; IRIS; MACROPHAGE; MONONUCLEAR CELL; NEUTROPHIL; NONHUMAN; PHOTORECEPTOR; RAT; T LYMPHOCYTE; UVEITIS; UVEORETINITIS;

EID: 0031464226     PISSN: 09273948     EISSN: None     Source Type: Journal    
DOI: 10.3109/09273949709085063     Document Type: Article

References (28)

1. McMenamin PG, Holthouse I. Immunohistochemical characterisation of dendritic cells and macrophages in the aqueous outflow pathways of the rat eye. Exp Eye Res 1992; 55:315-324.
2. Knisely TL, Anderson TM, Sherwood ME, Flotte TJ, Albert DM, Granstein RD. Morphologic and ultrastructural examination of 1-A+ cells in the murine iris. Invest Ophthalmol Vis Sci 1991; 32:2423-2431.
3. McMenamin PG, Holthouse I, Holt PG. Class II MHC (1a) antigen-bearing dendritic cells within the iris and ciliary body of the rat eye: distribution, phenotype, and relation to retinal microglia. Immunology 1992; 77:385-393.
4. McMenamin PG, Crewe J, Morrison S, Holt PG. Immunomorphological studies of macrophages and MHC class II-positive dendritic cells in the iris and ciliary body of the rat, mouse and human eye. Invest Ophthalmol Vis Sci 1994; 35:3234-3250.
5. Forrester JV, McMenamin PG, Holthouse I, Lumsden L, Liversidge J. Localisation and characterization of major histocompatibility complex class II-positive cells in the posterior segment of the eye: implications for induction of autoimmune uveoretinitis. Invest Ophthalmol Vis Sci 1994; 35:64-77.
6. Butler TL, McMenamin PG. Resident and infiltrating cells in the uveal tract in the early and late stages of experimental autoimmune uveoretinitis. Invest Ophthalmol Vis Sci 1996; 37:2195-2210.
7. McMenamin PG, Crewe J. Endotoxin-induced uveitis: kinetics and phenotype of the inflammatory cell infiltrate and the response of the resident tissue macrophages and dendritic cells in the iris and ciliary body. Invest Ophthalmol Vis Sci 1995; 36:1949-1959.
8. Yang P, De Vos A, Kijlstra A. Macrophages in the retina of normal Lewis rats and their dynamics after injection of LPS. Invest Ophthalmol Vis Sci 1996; 37:77-85.
9. Coupland SE, Krause L, Hoffmann F. The influence of penetrating keratoplasty and cyclosporin A therapy on MHC class II (Ia)-positive cells in the rat iris and choroid. Graefe's Arch Clin Exp Ophthalmol 1996; 234:116-124.
10. Broekhuyse RM, Kuhlmann ED, Winkens HJ, Van Vugt AHM. Experimental autoimmune anterior uveitis (EAAU), a new form of experimental uveitis. I. Induction by a detergent-insoluble, intrinsic protein fraction of the retinal pigment epithelium. Exp Eye Res 1991; 52:465-474.
11. Broekhuyse RM, Kuhlmann ED, Winkens HJ. Experimental autoimmune anterior uveitis (EAAU). II. Dose-dependent induction and adoptive transfer using a melanin-bound antigen of the retinal pigment epithelium. Exp Eye Res 1992; 55:401-411.
12. Chan CC, Hikita N, Dastgheib K, Whitcup SM, Gery I, Nussenblatt RB. Experimental melanin-protein-induced uveitis in the Lewis rat. Ophthalmology 1994; 101:1275-1280.
13. Bora NS, Kim MC, Kabeer NH, Simpson SC, Tandhasetti MT, Cirrito TP, Kaplan AD, Kaplan HJ. Experimental autoimmune anterior uveitis. Induction with melanin-associated antigen from the iris and ciliary body. Invest Ophthalmol Vis Sci 1995; 36:1056-1066.
14. Gery I, Streilein JW. Autoimmunity in the eye and its regulation. Curr Opin Immunol 1994; 6:938-945.
15. Kim MC, Kabeer NH, Tandhasetti MT, Kaplan HJ, Bora NS. Immunohostochemical studies on melanin associated antigen (MAA) induced experimental autoimmune anterior uveitis (EAAU). Curr Eye Res 1995; 14:703-710.
16. DeKozak Y, Sakai J, Thillaye B, Faure JP. S-antigen induced experimental autoimmune uveoretinitis in rats. Curr Eye Res 1981; 1:327-337.
17. McMenamin PG, Forrester JV, Steptoe RJ, Dua HS. Ultrastructural pathology of experimental autoimmune uveitis. Quantitative evidence of activation and possible high endothelial venule-like changes in retinal vascular endothelium. Lab Invest 1992; 67:42-55.
18. McMenamin PG, Forrester JV, Steptoe R, Dua HS. Ultrastructural pathology of experimental autoimmune uveitis in the rat. Autoimmunity 1993; 16:83-93.
19. Broekhuyse RM, Kuhlmann ED, Winkens HJ. Experimental autoimmune anterior uveitis (EAAU). III. Induction by immunization with purified uveal and skin melanins. Exp Eye Res 1993; 56:575-583.
20. Nussenblatt RB, Palestine AG. Uveitis: Fundamentals and Clinical Practice. Chicago, IL: USA Year Book Publishers, Inc., 1989.
21. Park S, Albert DM, Bolognia JL. Ocular manifestations of pigmentary disorders. Dermatol Clin 1992; 10:609-622.
22. 3. Immunology 1985; 54:589-599.
23. Damoiseaux, JGMC, Dopp, EA, Neefjes JJ, Beelen RHJ, Dijkstra CD. Heterogeneity of macrophages in the rat evidenced by variability in determinants: two new anti-rat macrophage antibodies against a heterodimer of 160 and 95 kd (CD11/CD18). J Leukocyte Biol 1989; 46:556-564.
24. Damoiseaux JGMC, Dopp EA, Calame D, Chao D, MacPherson GG, Dijkstra CD. Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1. Immunology 1994; 83:140-147.
25. Forrester JV, Borthwick G, McMenamin PG. Ultrastructural pathology of S-antigen induced uveitis. Invest Ophthalmol Vis Sci 1985; 26:1281-1292.
26. McMenamin PG, Broekhuyse RM, Forrester JV. Ultrastructural pathology of experimental autoimmune uveitis: a review. Micron 1993; 24:521-546.
27. Steptoe RJ, Holt PG, McMenamin PG. Origin and steady-state turnover of major histocompatibility complex class II-positive dendritic cells and resident-tissue macrophages in the iris of the rat eye. J Neuroimmunol 1996; 68:67-76.
28. Bamworth SD, Lightman SL, Greenwood J. Ultrastructrural analysis of interleukin-1-beta-induced leukocyte recruitment to the rat retina. Invest Ophthalmol Vis Sci 1997; 38:25-35.