Risperidone inhibits 5-hydroxytryptaminergic neuronal activity in the dorsal raphe nucleus by local release of 5-hydroxytryptamine

British Journal of Pharmacology

Volumn 122, Issue 8, 1997, Pages 1639-1646

  Hertel, Peter ^a   Nomikos, George G ^a   Svensson, Torgny H ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

5 hydroxytryptamine; Dorsal raphe nucleus; Electrophysiology; Microdialysis; Neuroleptic drugs; Spontaneous firing

Indexed keywords

ALPHA (2,3 DIMETHOXYPHENYL) 1 [2 (4 FLUOROPHENYL)ETHYL] 4 PIPERIDINEMETHANOL; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; AMPEROZIDE; CLOZAPINE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; FENCLONINE; IDAZOXAN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NEUROLEPTIC AGENT; PRAZOSIN; RACLOPRIDE; RISPERIDONE; SEROTONIN; SEROTONIN 1A ANTAGONIST; SEROTONIN 2A ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; INTRAVENOUS DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NERVE CELL INHIBITION; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONIN RELEASE;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; ANTIPSYCHOTIC AGENTS; CLOZAPINE; DOPAMINE ANTAGONISTS; HYDROXYINDOLEACETIC ACID; IDAZOXAN; MALE; PIPERAZINES; PRAZOSIN; PYRIDINES; RACLOPRIDE; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, SEROTONIN; RISPERIDONE; SALICYLAMIDES; SEROTONIN; SEROTONIN ANTAGONISTS;

EID: 0031464026     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701561     Document Type: Article

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