Systemic levels of 6-keto-prostaglandin F1α following administration of inhaled aerosolized prostacyclin

Anaesthesia and Intensive Care

Volumn 25, Issue 6, 1997, Pages 701-703

  Van Heerden, P V ^a  

^a SIR CHARLES GAIRDNER HOSPITAL   (Australia)

Author keywords

Critical care: prostacyclin, inhaled aerosolized; Lung: acute respiratory distress syndrome

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; PROSTACYCLIN;

ADULT; ARTICLE; CASE REPORT; GAS EXCHANGE; HEMODYNAMICS; HUMAN; HYPOXEMIA; INHALATIONAL DRUG ADMINISTRATION; MALE; RESPIRATORY DISTRESS; THROMBOCYTE AGGREGATION;

EID: 0031463563     PISSN: 0310057X     EISSN: None     Source Type: Journal    
DOI: 10.1177/0310057x9702500620     Document Type: Article

References (8)

1. Wetzel RC. Aerosolized prostacyclin: In search of the ideal pulmonary vasodilator. Anesthesiology 1995; 82:1315-1317.
2. van Heerden PV, Webb SAR, Hee G, Corkeron M, Thompson WR. Inhaled aerosolized prostacyclin as a selective pulmonary vasodilator for the treatment of severe hypoxaemia. Anaesth Intens Care 1996; 24:87-90.
3. Habler O, Kleen M, Zwissler B, et al. Inhalation of prostacyclin (PG12) for 8 hours does not produce signs of acute pulmonary toxicity in healthy lambs. Intens Care Med 1996; 22:426-433.
4. Murray JF, Matthay MA, Luce JM, Flick MR. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 1988; 138:720-723.
5. Barden A, Beilin LJ, Vandongen R, Rouse I. Influence of age, sex and potassium excretion on urinary prostaglandins. Clinical Sciences 1985; 68:601-604.
6. Burghuber OC, Silberbaucr K, Haber P, Sinzinger H, Elliott M, Leithner C. Pulmonary and antiaggregatory effects on prostacyclin after inhalation and intravenous infusion. Respiration 1984; 45:450-454.
7. Szczeklik A, Gryglewski RJ, Nizankowska E, Nizankowski R, Musial J. Pulmonary and anti-platelet effects of intravenous and inhaled prostacyclin in man. Prostaglandins 1978; 16:651-660.
8. van Heerden PV, Gibbs NM, Michaloupolos N. The effect of low concentrations of prostacyclin on platelet function in vitro. Anaesth Intens Care 1997; 25:343-346.