Interferon-α therapy alters glucose metabolism in patients with chronic hepatitis B

Journal of Medicine

Volumn 28, Issue 5-6, 1997, Pages 325-334

  Tanaka, Hisao ^a   Shiota, Goshi ^a   Kawasaki, Hironaka ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

Chronic hepatitis B; Glucose tolerance; Interferon

Indexed keywords

ALPHA INTERFERON;

ADULT; AGED; ARTICLE; AUTOIMMUNITY; CHRONIC HEPATITIS; CLINICAL ARTICLE; ENZYME ACTIVITY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; HEPATITIS B; HUMAN; IMMUNE RESPONSE; IMMUNOREACTIVITY; LIVER FUNCTION; LIVER METABOLISM; MALE;

ADULT; AGED; BLOOD GLUCOSE; FEMALE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HEPATITIS B, CHRONIC; HUMANS; INTERFERON-ALPHA; LIVER; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; RECOMBINANT PROTEINS;

EID: 0031463107     PISSN: 00257850     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Alexander, S.P. and Ralph, A.D. (1989).: Glucose and insulin metabolism in cirrhosis. J. Hepatology 8: 107-114.
2. Campbell, I.L., Oxbrow, L., Koulmanda, M. and Harrison, L.C. (1988).: IFNγ induces islet cell MHC antigen and enhances autoimmune, streptozocin-induced diabetes in the mouse. J. Immunol. 140: 1111-1116.
3. Cavallo-Perin, P., Cassader, M., Bozzo, A., Nuccio, P., Dall'Omo, A.M., Marucci, M. and Pagano, G. (1985).: Mechanism of insulin resistance in human liver cirrhosis. J. Clin. Invest. 75: 1659-1665.
4. Conlon, K.C., Urba, W.J., Smith, J.W., Steis, R.G., Longo, D.L. and Clark, J.W. (1990).: Exacerbation of symptoms of autoimmune disease in patients with receiving alpha-interferon therapy. Cancer 65: 2237-2242.
5. Fabris, P., Betterle, C., Floreani, A., Greggio, N.A., DeLazzari, F., Naccarato, R. and Chiaramonte, M. (1992).: Development of type 1 diabetes mellitus during interferon alpha therapy for chronic HCV hepatitis. Lancet 340: 548.
6. Foulis, A.K., Farquharson, M.A. and Meager, A. (1987).: Immunoreactive α-interferon in insulin-secreting β-cells in type I diabetes mellitus. Lancet 19: 1423-1427.
7. Giampaolo, B., Giulio, M., Marco, Z., Elisabetta, B., Andrea, F. and Emilio, P. (1994).: Prognostic significance of diabetes in patients with cirrhosis. Hepatology 20: 119-125.
8. Guerci, A-P. Guerci, B., Levy, Marchal, C., Ongagna, J., Ziegler, O., Candiloros, H., Guerci, O. and Drouin, P. (1994).: Onset of insulin-dependent diabetes mellitus after interferon-alpha therapy for hairy cell leukemia. Lancet 343: 1167.
9. Hoofnagle, J.H., Petes, M., Mullen, K.D., Jones, D.B., Rustgi, V.Di, Bischeglie, Hallahan, C., Park, Y., Meschievitz, C. and Jones, E.A. (1988).: Randomized controlled trial of recombinant human α interferon in patients with chronic hepatitis B. Gastroenterology 95: 1318-1325.
10. Johnson, R.N., Metcalf, P.A. and Backer, J.R. (1982).: Fructosamine: a new approach to the estimation of serum glycosylprotein. An index of diabetic control. Clin. Chim. Acta 127: 87-95.
11. Johnston, D.G., Albert, K.G.M.M., Wright, R., SmithLaing, G., Stewart, A.M., Sherlock, S., Faber, O. and Binder, C. (1978).: C-peptide and insulin in liver disease. Diabetes 27: 201-206.
12. Keller, U., Sonnenberg, G,E., Burckhardt, D. and Perruchoud, A. (1982).: Evidence for an augmented glucagon dependence of hepatic glucose production in cirrhosis of the liver. J. Clin. Endcrinol. Metab. 54: 961-968.
13. Knodell, R.G., Ishak, K.G., Black, W.C., Chen, T.S., Craig, R., Kaplowitz, N., Kiernan, T.W. and Wollman, J. (1981).: Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1: 106-112.
14. Kobayashi, T., Sugimoto, T., Ito, T., Kosaka, K., Tanaka, T., Suwa, S., Sato, K. and Tsuji, K. (1986).: The prevalence of islet cell antibodies in Japanese insulin-dependent and non-insulin dependent diabetic patients studied by indirect immunofluorescence and by a new method. Diabetes 35: 335-340.
15. Kosaka, K., Hagura, R., Kuzuya, T. and Kuzuya, N. (1974).: Insulin secretary response of diabetes mellitus during the period of improvement of glucose tolerance to normal range. Diabetologia 10: 775-782.
16. Kosaka, K. (1982): Diagnostic criteria for diabetes mellitus in Japan. From a report of the Japan Diabetes Society (JDS) committee on diagnosis of diabetes mellitus, 1982. Diabetes Res. Clin. Pract. 24: S59-S62.
17. Koivisto, V.A. (1992).: Interferon alpha and development of type 1 diabetus mellitus. Lancet 340: 1236.
18. Kruszynska, Y.T., Meyer-Alber, A., Darahshan, F., Home, P.D. and McIntype, N. (1993).: Metabolic handling of orally administered glucose in cirrhosis. J. Clin. Invest. 91: 1057-1066.
19. Mayet, W.S., Hes, G., Gerken, G., Rossol, S., Voth, R., Manns, M. and Meyer zum Buschenfelde (1989).: Treatment of chronic type B hepatitis with recombinant α interferon induces autoantibodies not specific for autoimmune chronic hepatitis. Hepatology 10: 24-28.
20. 1c described by a biokinetic model. Clin. Chim. Acta 136: 87-95.
21. Omagawa, A., Itoh, N., Hanafusa, T., Oda, Y., Waguri, M., Miyagawa, J., Kono., N., Kuwajima, M. and Matuzawa, Y. (1995).: Auto-immune endocrine disease induced by recombinant interferon-α therapy for hairly cell leukemia. Lancet 343: 1167.
22. Rabinovitch, A., Suarez-Pinzon, W.L., Sorensen, O., Bleackley, R.C. and Power, R.F. (1995).: IFNγ gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in non-obese diabetic mice. J. Immunol. 154: 4874-4882.
23. Shanker, T.P., Solomon, S.S., Duckworth, W.C., Himmelstein, S., Gray, S., Jerkins, T., Bobal, M.A. and Iyer, R.S. (1983).: Studies of glucose intolerance in cirrhosis of the liver. J. Lab. Clin. Med. 102: 459-469.
24. Shimizu, F., Shimizu, M. and Kamiyama, K. (1985).: Inhibitory effect of interferon on the production of insulin. Endocrinology 117: 2081-2084.
25. Shiota, G., Okano, J., Kawasaki, H., Kawamoto, T. and Nakamura, T. (1995).: Serum hepatocyte growth factor levels in liver diseases: clinical implications. Hepatology 21: 106-112.
26. Stewart, T.A., Hulgren, B., Huang, X., Pitts-Meek, S., Hully, J. and MacLachlam, N.J. (1993).: Induction of type I diabetes mellitus by interferon-α in transgenic mice. Science 260: 1942-1946.
27. Tine, F., Liberati, A., Craxi, A, Almasio, P. and Pagliaro, L. (1993).: Interferon treatment in patients with chronic hepatitis B: A meta-analysis of the published literature. J. Hepatol. 18: 154-162.
28. Veikko, A., Koivisto, V.A., Pelkonen, R. and Cantell, K. (1989).: Effect of interferon on glucose tolerance and insulin sensitivity. Diabetes 38: 641-647.