Ki-67 immunoexpression is a robust marker of proliferative cells in the rat

Laboratory Investigation

Volumn 77, Issue 6, 1997, Pages 697-698

  Gerlach, Christiane ^a   Golding, Matthew ^b   Larue, Lionel ^c   Alison, Malcolm R ^b   Gerdes, Johannes ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c INSTITUT CURIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

KI 67 ANTIGEN; MONOCLONAL ANTIBODY KI 67;

ADOLESCENT; ANTIBODY LABELING; ARTICLE; CELL PROLIFERATION; EMBRYO; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RAT; TECHNIQUE;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL DIVISION; KI-67 ANTIGEN; RATS;

EID: 0031461106     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Alison MR (1995). Assessing cellular proliferation: What's worth measuring? Hum Exp Toxicol 14:935-944.
2. Brown DC and Gatter KC (1990). Monoclonal antibody Ki-67: Its use in histopathology. Histopathology 17:489-503.
3. Cordell JL, Falini B, Erber WN, Ghosh AK, Abulaziz Z, MacDonald S, Pulford KAF, Stein H, and Mason DY (1984). Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 32:219-229.
4. Gerdes J, Schwab U, Lemke H, and Stein H (1983). Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 31:13-20.
5. Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, and Stein H (1984). Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 133:1710-1715.
6. Gerdes J, Li L, Schlüter C, Duchrow M, Wohlenberg C, Gertach C, Stahmer I, Kloth S, Brandt E, and Flad HD (1991). Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. Am J Pathol 138:867-873.
7. Key G, Becker MHG, Baron B, Duchrow M, Schlüter C, Flad HD, and Gerdes J (1993). New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 66 bp repetitive elements encoding for the Ki-67 epitope. Lab Invest 68:629-635.
8. Schlüter C, Duchrow M, Wohlenberg C, Becker MHG, Key G, Flad HD, and Gerdes J (1993). The cell proliferation-associated antigen of antibody Ki-67: A very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle maintaining proteins. J Cell Biol 123:513-522.