Release of unaltered bases from polycrystalline pyrimidine DNA constituents after X-irradiation and bombardment with heavy ions

International Journal of Radiation Biology

Volumn 72, Issue 6, 1997, Pages 735-744

  Hoffmann, A K ^a   Huttermann J ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE PHOSPHATE; DEOXYCYTIDINE PHOSPHATE; DNA; DNA BASE; NITROGEN; PYRIMIDINE NUCLEOTIDE; THYMIDINE PHOSPHATE;

ARTICLE; ELECTRON SPIN RESONANCE; FREEZE DRYING; HEAVY ION RADIATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RADIATION DOSE; RADIATION RESPONSE; X IRRADIATION;

DEOXYCYTIDINE MONOPHOSPHATE; DNA; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; THYMIDINE MONOPHOSPHATE; X-RAYS;

EID: 0031460133     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530097142898     Document Type: Article

References (14)

1. BERNHARD, W. A., MROZKA, N. and BARNES, J., 1994, Combination is the dominant free radical process initiated in DNA by ionizing radiation: an overview based on solid-state EPR studies. International Journal of Radiation Biology, 66, 491-497.
2. DEEBLE, D. J., SCHULZ, D. and VON SONNTAG, C., 1986, Reactions of OH radicals with poly(U) in deoxygenated solutions: sites of OH radical attack and the kinetics of base release. International Journal of Radiation Biology, 49, 915-926.
3. DUSEMUND, B., 1997, Free radicals from solid nucleotides and nucleotide mixtures as studied by EPQ spectroscopy. PhD-thesis, Universität des Saarlandes.
4. HENLE, E. S., ROOTS, R., HOLLEY, W. R. and CHATTERJEE, A., 1995, DNA stand breakage is correlated with unaltered base release after gamma irradiation. Radiation Research, 143, 144-150.
5. 2O-saturated aqueous solutions: release of undamaged and modified bases. Radiation Research, 134, 283-294.
6. HÜTTERMANN, J. and SCHAEFER, A., 1989, Heavy ion induced free radical formation in solid DNA-constituents: quantitative and structural aspects. International Journal of Applied Instruments. Part A: Applied Radiation Isotopes, 40, 915-921.
7. HÜTTERMANN, J., SCHAEFER, A. and KRAFT, G., 1989, Free radicals induced in solid DNA by heavy ion bombardment. Advance Space Research, 9, 35-44.
8. PAUL, C. R., BELFI, C. A., ARAKALI, A. V. and BOX, H. C., 1987, Radiation damage to dinucleoside monophosphates: mediated versus direct damage. International Journal of Radiation Biology, 51, 103-114.
9. ROOTS, R., HENLE, E., HOLLEY, W. R. and CHATTERJEE, A., 1991, Measurements of nucleic bases released after γ-irradiation of DNA in solution in air. Radiation Research, 125, 288-292.
10. SCHAEFER, A., HÜTTERMANN, J. and KRAFT, G., 1993, Free radicals from polycrystalline pyrimidines and purines upon heavy ion bombardment at low temperatures: an electron spin resonance study. International Journal of Radiation Biology, 63, 139-149.
11. SHARPATYI, V. A., CADET, J. and TEOULE, R., 1978, Final products obtained from the gamma radiolysis of frozen aqueous solutions of thymidine. International Journal of Radiation Biology, 33, 419-423.
12. SHAW, A. A. and CADET, J., 1996, Direct effects of γ-radiation on 2′-deoxycytidine in frozen aqueous solution. International Journal of Radiation Biology, 70, 1-6.
13. SHAW, A. A., VOITURIEZ, L., CADET, J., GREGOLI, S. and SYMONS, M. C. R., 1988, Identification of the products resulting from the direct effects of γ-radiation on thymidine. Journal of the Chemical Society, Perkin Transactions II, 1303-1307.
14. SWARTS, S. G., SEVILLA, M., BECKER, D., TOKAR, C. J. and WHEELER, K. T., 1992, Radiation-induced DNA damage as a function of hydration. I. Release of unaltered bases. Radiation Research, 129, 333-344.