메뉴 건너뛰기




Volumn 75, Issue 4, 1997, Pages 415-423

Effects of a calcium antagonist, lacidipine, on experimental focal cerebral ischemia in rats

Author keywords

Calcium antagonist; Cerebral blood flow; Energy metabolism; Focal cerebral ischemia; Lacidipine

Indexed keywords

GLUCOSE; LACIDIPINE; LACTIC ACID; NICARDIPINE; PYRUVIC ACID; TRIPHENYLTETRAZOLIUM;

EID: 0031460114     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.75.415     Document Type: Article
Times cited : (12)

References (29)
  • 1
    • 0021043252 scopus 로고
    • Comparison of the cardiovascular effect of FR34235, a new dihydropyridine, with other calcium antagonist
    • Ohtsuka M, Ono T, Hiroi J, Esumi K, Kikuchi H and Kumada S: Comparison of the cardiovascular effect of FR34235, a new dihydropyridine, with other calcium antagonist. J Cardiovasc Pharmacol 5, 1074-1082 (1983)
    • (1983) J Cardiovasc Pharmacol , vol.5 , pp. 1074-1082
    • Ohtsuka, M.1    Ono, T.2    Hiroi, J.3    Esumi, K.4    Kikuchi, H.5    Kumada, S.6
  • 2
    • 0017089637 scopus 로고
    • Vasodilator profile of a new 1,4-dihydropyridine derivative, 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)]-ehtyl ester 5-methyl ester hydrochloride (YC-93)
    • Takenaka T, Usuda S, Nomura T, Maeno H and Sado T: Vasodilator profile of a new 1,4-dihydropyridine derivative, 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)]-ehtyl ester 5-methyl ester hydrochloride (YC-93). Arzneimttelforschung 26, 2172-2178 (1976)
    • (1976) Arzneimttelforschung , vol.26 , pp. 2172-2178
    • Takenaka, T.1    Usuda, S.2    Nomura, T.3    Maeno, H.4    Sado, T.5
  • 3
    • 0023900649 scopus 로고
    • Prevention of ischemic and postischemic brain edema by a novel calcium antagonist (PN-200-110)
    • Abe K, Kogure K and Watanabe T: Prevention of ischemic and postischemic brain edema by a novel calcium antagonist (PN-200-110). J Cereb Blood Flow Metab 8, 436-439 (1988)
    • (1988) J Cereb Blood Flow Metab , vol.8 , pp. 436-439
    • Abe, K.1    Kogure, K.2    Watanabe, T.3
  • 4
    • 0023713701 scopus 로고
    • Nicardipine reduces calcium accumulation and electrolyte derangements in regional cerebral ischemia in rats
    • Hadani M, Yong W and Flamm ES: Nicardipine reduces calcium accumulation and electrolyte derangements in regional cerebral ischemia in rats. Stroke 19, 1125-1132 (1988)
    • (1988) Stroke , vol.19 , pp. 1125-1132
    • Hadani, M.1    Yong, W.2    Flamm, E.S.3
  • 5
    • 0019842691 scopus 로고
    • Cell damage in the brain: A speculative synthesis
    • Siesjö BK: Cell damage in the brain: a speculative synthesis. J Cereb Blood Flow Metab 1, 155-185 (1981)
    • (1981) J Cereb Blood Flow Metab , vol.1 , pp. 155-185
    • Siesjö, B.K.1
  • 6
    • 0020684635 scopus 로고
    • The pathophysiology of brain ischemia
    • Raichle ME: The pathophysiology of brain ischemia. Ann Neurol 13, 2-10 (1983)
    • (1983) Ann Neurol , vol.13 , pp. 2-10
    • Raichle, M.E.1
  • 7
    • 0025918220 scopus 로고
    • Nilvadipine, a new calcium channel blocker, reduces ischemic brain injury in rats
    • Takakura S, Susumu T, Satoh H, Mori J, Shiino A and Handa J: Nilvadipine, a new calcium channel blocker, reduces ischemic brain injury in rats. Jpn J Pharmacol 56, 547-550 (1991)
    • (1991) Jpn J Pharmacol , vol.56 , pp. 547-550
    • Takakura, S.1    Susumu, T.2    Satoh, H.3    Mori, J.4    Shiino, A.5    Handa, J.6
  • 8
    • 0023225212 scopus 로고
    • The therapeutic value of nimodipine in experimental focal cerebral ischemia
    • Germano IM, Bartkowski HM, Cassel ME and Pitts LH: The therapeutic value of nimodipine in experimental focal cerebral ischemia. J Neurosurg 67, 81-87 (1987)
    • (1987) J Neurosurg , vol.67 , pp. 81-87
    • Germano, I.M.1    Bartkowski, H.M.2    Cassel, M.E.3    Pitts, L.H.4
  • 9
    • 0024538955 scopus 로고
    • Cerebrovascular, biochemical, and cytoprotective effects of isradipine in laboratory animals
    • Sauter A, Rudin M, Wiederhold K-H and Hof RP: Cerebrovascular, biochemical, and cytoprotective effects of isradipine in laboratory animals. Am J Med 86, Suppl 4A, 134-146 (1989)
    • (1989) Am J Med , vol.86 , Issue.SUPPL. 4A , pp. 134-146
    • Sauter, A.1    Rudin, M.2    Wiederhold, K.-H.3    Hof, R.P.4
  • 10
    • 0025255628 scopus 로고
    • Lacidipine: A calcium antagonist with potent and long-lasting antihypertensive effects in animal studies
    • Micheli D, Collodel A, Semeraro C, Gaviraghi G and Carpi C: Lacidipine: A calcium antagonist with potent and long-lasting antihypertensive effects in animal studies. J Cardiovasc Pharmacol 15, 666-675 (1990)
    • (1990) J Cardiovasc Pharmacol , vol.15 , pp. 666-675
    • Micheli, D.1    Collodel, A.2    Semeraro, C.3    Gaviraghi, G.4    Carpi, C.5
  • 11
    • 0027234761 scopus 로고
    • In vitro effects of the new calcium antagonist lacidipine
    • Kawada T, Sun H-T, Nakazawa M and Imai S: In vitro effects of the new calcium antagonist lacidipine. Jpn J Pharmacol 62, 289-296 (1993)
    • (1993) Jpn J Pharmacol , vol.62 , pp. 289-296
    • Kawada, T.1    Sun, H.-T.2    Nakazawa, M.3    Imai, S.4
  • 12
    • 0029912617 scopus 로고    scopus 로고
    • Effects of lacidipine, a new dihydropyridine derivative, on various cerebral ischemia models
    • Abstr in English
    • Funato H, Katsuki Y, Yano T, Kawano H, Akada Y, Sato M and Uemura A: Effects of lacidipine, a new dihydropyridine derivative, on various cerebral ischemia models. Folia Pharmacol Jpn 108, 243-257 (1996) (Abstr in English)
    • (1996) Folia Pharmacol Jpn , vol.108 , pp. 243-257
    • Funato, H.1    Katsuki, Y.2    Yano, T.3    Kawano, H.4    Akada, Y.5    Sato, M.6    Uemura, A.7
  • 14
    • 0019868418 scopus 로고
    • Foca cerebral ischemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion
    • Tamura A, Graham DI, McCulloch J and Teasdale GM: Foca cerebral ischemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1, 53-60 (1981)
    • (1981) J Cereb Blood Flow Metab , vol.1 , pp. 53-60
    • Tamura, A.1    Graham, D.I.2    McCulloch, J.3    Teasdale, G.M.4
  • 15
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination
    • Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL and Bartkowski H: Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination Stroke 17, 472-476 (1986)
    • (1986) Stroke , vol.17 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3    Nishimura, M.C.4    Davis, R.L.5    Bartkowski, H.6
  • 17
    • 0018358068 scopus 로고
    • Effects of psychotropic drugs on pressor and behavioral responses to brain stimulation in unrestrained, unanesthetized rats
    • Kawasaki H, Watanabe S and Ueki S: Effects of psychotropic drugs on pressor and behavioral responses to brain stimulation in unrestrained, unanesthetized rats. Pharmacol Biochem Behav 10, 907-915 (1979)
    • (1979) Pharmacol Biochem Behav , vol.10 , pp. 907-915
    • Kawasaki, H.1    Watanabe, S.2    Ueki, S.3
  • 18
    • 0000375693 scopus 로고
    • Measurement of local cerebral blood flow with hydrogen gas
    • Auckland K, Bower BF and Berliner RW: Measurement of local cerebral blood flow with hydrogen gas. Circ Res 14, 164-187 (1964)
    • (1964) Circ Res , vol.14 , pp. 164-187
    • Auckland, K.1    Bower, B.F.2    Berliner, R.W.3
  • 19
    • 0026773770 scopus 로고
    • Benefical effects of naftidrofuryl oxalate on brain regional energy after microsphere-induced cerebral embolism
    • Miyake K, Taguchi T, Tanonaka K, Horiguchi T, Takagi N and Takeo S: Benefical effects of naftidrofuryl oxalate on brain regional energy after microsphere-induced cerebral embolism. J Pharmacol Exp Ther 260, 1058-1066 (1992)
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 1058-1066
    • Miyake, K.1    Taguchi, T.2    Tanonaka, K.3    Horiguchi, T.4    Takagi, N.5    Takeo, S.6
  • 21
    • 0014353859 scopus 로고
    • The energy charge of the adenylate pool as a regulatory parameter: Interaction with feedback modifiers
    • Atkinson DE: The energy charge of the adenylate pool as a regulatory parameter: Interaction with feedback modifiers. Biochem 7, 4030-4034 (1968)
    • (1968) Biochem , vol.7 , pp. 4030-4034
    • Atkinson, D.E.1
  • 23
    • 0021180170 scopus 로고
    • Extracellular pH, potassium, and calcium activities in progressive ischemia of rat cortex
    • Harris RJ and Symon L: Extracellular pH, potassium, and calcium activities in progressive ischemia of rat cortex. J Cereb Blood Flow Metab 4, 178-186 (1984)
    • (1984) J Cereb Blood Flow Metab , vol.4 , pp. 178-186
    • Harris, R.J.1    Symon, L.2
  • 25
    • 0026601272 scopus 로고
    • Focal and perifocal changes in tissue energy state during middle cerebral artery occlusion in normo- and hyperglycemic rats
    • Folbergrova J, Memezawa H, Smith M-L and Siesjo BK: Focal and perifocal changes in tissue energy state during middle cerebral artery occlusion in normo- and hyperglycemic rats. J Cereb Blood Flow Metab 12, 25-33 (1992)
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 25-33
    • Folbergrova, J.1    Memezawa, H.2    Smith, M.-L.3    Siesjo, B.K.4
  • 26
    • 0025950408 scopus 로고
    • Ischemic threshold of cerebral protein synthesis and energy state following middle cerebral artery occlusion in rats
    • Mies G, Ishimura S, Xie Y, Seo K and Hossmann K-A: Ischemic threshold of cerebral protein synthesis and energy state following middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab 11, 753-761 (1991)
    • (1991) J Cereb Blood Flow Metab , vol.11 , pp. 753-761
    • Mies, G.1    Ishimura, S.2    Xie, Y.3    Seo, K.4    Hossmann, K.-A.5
  • 27
    • 0024149117 scopus 로고
    • Reduction of neuronal damage in irreversible cerebral ischemia by Ca antagonist
    • Sauter A, Rudin M and Wiederhold K-H: Reduction of neuronal damage in irreversible cerebral ischemia by Ca antagonist. Neurochem Pathol 9, 211-236 (1988)
    • (1988) Neurochem Pathol , vol.9 , pp. 211-236
    • Sauter, A.1    Rudin, M.2    Wiederhold, K.-H.3
  • 28
    • 0023727353 scopus 로고
    • Calcium channel blockers correct acidosis in ischemic rat brain without altering cerebral blood flow
    • Berger L and Hakim A: Calcium channel blockers correct acidosis in ischemic rat brain without altering cerebral blood flow. Stroke 19, 1257-1261 (1988)
    • (1988) Stroke , vol.19 , pp. 1257-1261
    • Berger, L.1    Hakim, A.2
  • 29
    • 2642682555 scopus 로고
    • The effect of oral administration of Ca-antagonist (Nilvadipine) on cerebral blood flow and metabolism in experimental brain ischemia
    • Abstr in English
    • Yoshinaga M, Sadoshima S, Ibayashi S, Ishituka T and Fujishima M: The effect of oral administration of Ca-antagonist (Nilvadipine) on cerebral blood flow and metabolism in experimental brain ischemia. Jpn J Stroke 13, 333-340 (1991) (Abstr in English)
    • (1991) Jpn J Stroke , vol.13 , pp. 333-340
    • Yoshinaga, M.1    Sadoshima, S.2    Ibayashi, S.3    Ishituka, T.4    Fujishima, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.