Thermodynamics of partitioning of the antimalarial drug mefloquine in phospholipid bilayers and bulk solvents

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 12, 1997, Pages 2055-2060

  Go, Mei Lin ^a   Ngiam, Tong Lan ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Dimyristoylphosphatidylcholine bilayers; Mefloquine; Octanol; Quinine; Thermodynamics of partitioning

Indexed keywords

ANTIMALARIAL AGENT; DIMYRISTOYLPHOSPHATIDYLCHOLINE; HEXANE; MEFLOQUINE; OCTANOL; PHOSPHOLIPID; QUININE;

ARTICLE; DRUG BINDING; DRUG CONFORMATION; DRUG DISCRIMINATION; DRUG MECHANISM; ENTHALPY; ENTROPY; MALARIA FALCIPARUM; PHOSPHOLIPID BILAYER; THERMODYNAMICS;

EID: 0031459897     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.2055     Document Type: Article

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