Inhibition of HMG-CoA reductase by atorvastatin decreases both VLDL and LDL apolipoprotein B production in miniature pigs

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 11, 1997, Pages 2589-2600

  Burnett, John R ^a   Wilcox, Lisa J ^a   Telford, Dawn E ^a   Kleinstiver, Sandra J ^a   Barrett, P Hugh R ^b   Newton, Roger S ^c   Huff, Murray W ^a  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WASHINGTON   (United States)

^c PFIZER INC   (United States)

Author keywords

Apolipoprotein B metabolism; Atorvastatin; HMO CoA reductase inhibitor; Kinetics; mRNA

Indexed keywords

APOLIPOPROTEIN B; ATORVASTATIN; CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATABOLISM; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; ENZYME INHIBITION; LIPOPROTEIN SECRETION; LIPOPROTEIN SYNTHESIS; LIVER; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SMALL INTESTINE; SWINE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0031459889     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.11.2589     Document Type: Article

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