Genetic remodeling of gangliosides resulted in the enhanced reactions to the foreign substances in skin

Glycobiology

Volumn 7, Issue 8, 1997, Pages 1111-1120

  Fukumoto, Satoshi ^a   Yamamoto, Akihito ^a   Hasegawa, Tomokazu ^a   Abe, Kuniko ^a   Takamiya, Kogo ^a   Okada, Masahiko ^a   Min, Zhao Jin ^a   Furukawa, Keiko ^b   Miyazaki, Hiroshi ^a   Tsuji, Yoshiro ^a   Goto, George ^a   Suzuki, Misao ^c   Shiku, Hiroshi ^b   Furukawa, Koichi ^a,d  

^a NAGASAKI UNIVERSITY   (Japan)

^b MIE UNIVERSITY   (Japan)

^c KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^d NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Ganglioside; GD2 synthase; Glycosyltransferase; GM2; Skin; Transgenic mouse

Indexed keywords

GANGLIOSIDE; GANGLIOSIDE GM1; GANGLIOSIDE GM3;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; FOREIGN BODY; GENE EXPRESSION; INFLAMMATORY INFILTRATE; LIPID ANALYSIS; LIVER; MOUSE; NEUTROPHIL; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; SKIN INFLAMMATION; SPLEEN; THYMUS; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

ANIMALS; BRAIN; DERMATITIS; GANGLIOSIDES; GENE EXPRESSION; GENETIC ENGINEERING; MICE; MICE, TRANSGENIC; N-ACETYLGALACTOSAMINYLTRANSFERASES; NEUTROPHILS; ORGAN SPECIFICITY; RNA, MESSENGER; SILICON; SKIN; SUPEROXIDES; SURGICAL FLAPS;

EID: 0031459859     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/7.8.1111     Document Type: Article

References (47)

1. Berenson, C.S. and Ryan, J.L. (1991) Murine peritoneal macrophage gangliosides inhibit lymphocyte proliferation. J. Leukoc. Biol., 50, 393-401.
2. Bry, L., Falk, P.G. and Gordon, J.I. (1996) Genetic engineering of carbohydrate biosynthetic pathways in transgenic mice demonstrates cell cycle-associated regulation of glycoconjugate production in small intestinal epithelial cells. Proc. Natl. Acad. Sci. USA, 93, 1161-1166.
3. Coetzee, T., Fujita, N., Dupree, J., Shi, R., Blight, A., Suzuki, K., Suzuki, K. and Popko, B. (1996) Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability. Cell, 86, 209-219.
4. Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analyt. Biochem., 162, 156-159.
5. Demetriou, M., Nabi, I.R., Coppolino, M., Dedhar, S. and Dennis, J.W. (1995) Reduced contact-inhibition and substratum adhesion in epithelial cells expressing GlcNAc-transferase V. J. Cell. Biol., 130, 383-392.
6. Hakomori, S. (1981) Glycosphingolipids in cellular interaction, differentiation, and oncogenesis. Annu. Rev. Biochem., 50, 733-764.
7. Hammond, D.C., Brooksher, R.D., Mann, R.J. and Beernink, J.H. (1993) The dorsal skin-flap model in the rat: Factors influencing survival. Plast. Reconstr. Surg., 91, 316-321.
8. Hennet, T., Hagen, F.K., Tabak, L.A., Marth, J.D. (1995) T-Cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination. Proc. Natl. Acad. Sci. USA, 92, 12070-12074.
9. Ichikawa, S., Nakajo, N. Sakiyama, H. and Hirabayashi, Y. (1994) A mouse B16 melanoma mutant deficient in glycolipids. Proc. Natl. Acad. Sci. USA, 91, 2703-2707.
10. Ikematsu, S., Kaname, T., Ozawa, M., Yonezawa, S., Sato, E., Uehara, F., Obama, H., Yamamura, K. and Muramatsu, T. (1993) Transgenic mouse lines with ectopic expression of α-1,3-galactosyltransferase: production and characteristics. Glycobiology, 3, 575-580.
11. Ioffe, E. and Stanley, P. (1994) Mice lacking N-acetyl-glucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates. Proc. Natl. Acad. Sci. USA, 91, 728-732.
12. Ito, M. and Komori, H. (1996) Homeostasis of cell-surface glycosphingolipid content in B16 melanoma cells. Evidence revealed by an endoglycoceramidase. J. Biol. Chem., 271, 12655-12660.
13. Koyama, T. and Hughes, R.C. (1992) Functional integrins from normal and glycosylation-deficient baby hamster kidney cells. Terminal processing of asparagine-linked oligosaccharides is not correlated with fibronectin-binding activity. J. Biol. Chem., 267, 25939-25944.
14. Ledeen, R.W., Wu, G., Cannella, M.S., Oderfeld-Nowak, B. and Cuello, A.C. (1990) Gangliosides as neurotrophic agents: studies on the mechanism of action. Acta Neurobiol. Exp., 50, 439-449.
15. Maly, P., Thall, A.D., Petryniak, B., Rogers, C.E., Smith, P.L., Marks, R.M., Kelly, R.J., Gersten, K.M., Cheng, G., Saunders, T.L., Camper, S.A., Camphausen, R.T., Sullivan, F.X., Isogai, Y., Hindsgaul, O., von Andrian, U.H. and Lowe, J.B. (1996) The α(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell, 86, 643-653.
16. Marth, J.D. (1994) Will the transgenic mouse serve as a Rosetta Stone to glycoconjugate function? Clycoconj. J., 11, 3-8.
17. Mbawuike, I.N. and Herscowitz, H.B. (1988) The role of membrane gangliosides in murine alveolar macrophage-mediated suppression of the immune response. Cell Immunol., 112, 174-186.
18. Metzler, M., Gertz, A., Sarkar, M., Schachter, H., Schrader, J.W. and Marth, J.D. (1994) Complex asparagin-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J., 13, 2056-2065.
19. Nagata, Y., Yamashiro, S., Yodoi, J., Lloyd, K.O., Shiku, H. and Furukawa, K. (1992) Expression cloning of β1,4N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides. J. Biol. Chem., 267, 12082-12089.
20. Narimatsu, H., Sinha, S., Brew, K., Okayama, H. and Qasba, P.K. (1986) Cloning and sequencing of cDNA of bovine N acetylglucosamine (beta 1-4)galactosyltransferase. Proc. Natl. Acad. Sci. USA, 83, 4720-4724.
21. Neefjes, J.J., DeBruijin, M.L.H., Boog, C.J.P., Nieland, J.D., Boes, J., Melief, C.J.M. and Ploegh, H.L. (1990) N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response. J. Exp. Med., 171, 583-588.
22. Niwa, H., Yamamura, K. and Miyazaki, J. (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene, 108, 193-200.
23. Nojiri, H., Takaku, F., Terui, Y., Miura, Y. and Saito, M. (1986) Ganglioside GM3: an acidic membrane component that increases during macrophage-like differentiation can induce monocytic differentiation of human myeloid and monocytoid leukemic cell lines HL-60 and U937. Proc. Natl. Acad. Sci. USA. 83, 782-786.
24. Paller, A.S., Arnsmeier, S.L., Alvarez-Franco, M. and Bremer, E.G. (1993) Ganglioside GM3 inhibits proliferation of cultured keratinocytes. J. Invest. Dermatol., 100, 841-845.
25. Paller, A.S., Arnsmeier, S.L., Chen, J.D. and Woodley, D.T. (1995a) Ganglioside GT1b inhibits keratinocyte adhesion and migration on a fibronectin matrix. J. Invest. Dermatol., 105, 237-242.
26. Paller, A.S., Arnsmeier, S.L., Fisher, G.J. and Yu, Q.C. (1995b) Ganglioside GT1b induces keratinocyte differentiation without activating protein kinase C. Exp. Cell Res., 217, 118-124.
27. Pohlentz, G., Klein, D., Schwarzmann, G., Schmitz, D. and Sandhoff, K. (1988) Both GA2, GM2, and GD2 synthases and GM1b, GD1a, and GT1b synthases are single enzymes in Golgi vesicles from rat liver. Proc. Natl. Acad. Sci. USA, 85, 7044-7048.
28. Prieto, P.A., Mukerji, P., Kedler, B., Erney, R., Gonzalez, D., Yun, J.S., Smith, D.F., Moremen, K.W., Nardelli, C., Pierce, M., Li, Y., Chen, X., Wagner, T.E., Cummings, R.D. and Kopchick, J.J. (1995) Remodeling of milk glycoconjugate by transgenic expression of a human glycosyltransferase. J. Biol. Chem., 270, 29515-29519.
29. Raju, T.S., Ray, M.K. and Stanley, P. (1995) LEC18, a dominant Chinese hamster ovary glycosylation mutant synthesizes N-linked carbohydrates with a novel core structure. J. Biol. Chem., 270, 30294-302302.
30. Ryan, J.L., Gobran, L. and Morrison, D.C. (1986) Modulation of murine macrophage metabolism by glycolipids: inhibition of LPS-induced metabolism by specific gangliosides. J. Leukoc. Biol., 40, 367-379.
31. Sandrin, M.S., Fodor, W.L., Mouhtouris, E., Osman, N., Cohney, S., Rollins, S.A., Guilmette, E.R., Setter, E., Squinto, S.P. and McKenzie, I.F. (1995) Enzymatic remodeling of the carbohydrate surface of a xenogenic cell substantially reduces human antibody binding and complement-mediated cytolysis. Nature Med., 1, 1261-1267.
32. Schneider, J.S., Pope, A., Simpson, K., Taggart, J., Smith, M.G., DiStefano, L. (1992) Recovery from experimental parkinsonism in primates with GM1 ganglioside treatment. Science, 256, 843-846.
33. Stanley, P. and Ioffe, E. (1995) Glycosyltransferase mutants: key to new insights in glycobiology. FASEB J., 9, 1436-1444.
34. Svennerholm, L. (1963) Chromatographic separation of human brain gangliosides. J. Neurochem., 10, 613-623.
35. Takamiya, K., Yamamoto, A., Yamashiro, S., Furukawa, K., Haraguchi, M., Okada, M., Ikeda, T., Shiku, H. and Furukawa, K. (1995) T cell receptor-mediated stimulation of mouse thymocytes induces up-regulation of the GM2/GD2 synthase gene. FEBS Lett., 358, 79-83.
36. Takamiya, K., Yamamoto, A., Furukawa, K., Yamashiro, S., Shin, M., Okada, M., Fukumoto, S., Haraguchi, M., Takeda, N., Fujimura, K., Sakae, M., Kishikawa, M., Shiku, H., Furukawa, K. and Aizawa, S. (1996) Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system. Proc. Natl. Acad. Sci. USA, 93, 10662-10667.
37. Tsui, Z.C., Hou, W.H., Yang, L. and Zhu, Z.M. (1990) Effect of a cell differentiation inducer, ganglioside GM3, on the neutral glycosphingolipid composition and cell membrane fluidity of a human promyelocytic leukemia cell line HL-60. In Vivo, 4, 205-208.
38. Tsuji, S., Arita, M. and Nagai, Y. (1983) GQ1b, a bioactive ganglioside that exhibits novel nerve growth factor (NGF)-like activities in the two neuroblastoma cell lines. J. Biochem., 94, 303-306.
39. Varki, A., Hooshmand, F., Diaz, S., Varki, N.M. and Hedrick, S.M. (1991) Developmental abnormalities in transgenic mice expressing a sialic acid-specific 9-O-acetylesterase. Cell, 65, 65-74.
40. Wiegandt, H. (1985) Gangliosides. In Wiegandt, H. (ed.), Glycolipids, Elsevier, Amsterdam, pp. 199-260.
41. Yamamoto, A., Atsuta, M. and Hamatani, K. (1992) Restricted expression of recombination activating gene (RAG-1) in mouse lymphoid tissues. Cell Biochem. Funct., 10, 71-77.
42. Yamamoto, A., Haraguchi, M., Yamashiro, S., Fukumoto, S., Furukawa, K., Takamiya, K., Atsuta, M., Shiku, S. and Furukawa, K. (1996) Heterogeneity in the expression pattern of two ganglioside synthase genes during mouse brain development. J. Neurochem., 66, 26-34.
43. Yamashiro, S., Shutian, R., Furukawa, K., Tai, T., Lloyd, K.O., Shiku, H. and Furukawa, K. (1993) Genetic and enzymatic basis for the differential expression of GM2 and GD2 gangliosides in human cancer cell lines. Cancer Res., 53, 5395-5400.
44. Yamashiro, S., Haraguchi, M., Furukawa, K., Takamiya, K., Yamamoto, A., Nagata, Y., Lloyd, K.O., Shiku, H. and Furukawa K. (1995) Substrate specificity of β1,4-N-acetylgalactosaminyl-transferase in vitro and in cDNA-transfected cells. GM2/GD2 synthase efficiently generates asialo-GM2 in certain cells. J. Biol. Chem., 270, 6149-6155.
45. Yohe, H.C., Coleman, D.L. and Ryan, J.L. (1985) Ganglioside alterations in stimulated murine macrophages. Biochem. Biophys. Acta, 818, 81-86.
46. Yoshimura, M., Nishikawa, A., Ihara, Y., Taniguchi, S. and Taniguchi, N. (1995) Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection. Proc. Natl. Acad. Sci. USA. 92, 8754-8758.
47. Youakim, A., Hathaway, H.J., Miller, D.J., Gong, X. and Shur, B.D. (1994) Overexpressing sperm surface β1,4-galactosyltransferase in transgenic mice affects multiple aspects of sperm-egg interactions. J. Cell Biol., 126, 1573-1583.