Suppression of lipid transfer inhibitor protein activity by oleate: A novel mechanism of cholesteryl ester transfer protein regulation by plasma free fatty acids

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 11, 1997, Pages 3041-3048

  Morton, Richard E ^a   Greene, Diane J ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Cholesteryl ester transfer protein; Free fatty acid; Lipid transfer inhibitor protein

Indexed keywords

CHOLESTEROL ESTER TRANSFER PROTEIN; FATTY ACID; HIGH DENSITY LIPOPROTEIN; LIPID TRANSFER PROTEIN; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; OLEIC ACID; PROTEIN INHIBITOR; VERY LOW DENSITY LIPOPROTEIN;

ARTICLE; FATTY ACID BLOOD LEVEL; HUMAN; LIPID METABOLISM; LIPID TRANSPORT; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 0031459464     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.11.3041     Document Type: Article

References (15)

1. Morton RE. Interaction of lipid transfer protein with plasma lipoproteins and cell membranes. Experientia. 1990;46:552-560.
2. Tall A. Plasma lipid transfer proteins. Annu Rev Biochem. 1995;64:235-257.
3. McPherson R, Mann CJ, Tall AR, Hogue M, Martin L, Milne RW, Marcel YL. Plasma concentrations of cholesteryl ester transfer protein in hyperlipoproteinemia: relation to cholesteryl ester transfer protein activity and other lipoprotein variables. Arterioscler Thromb. 1991;11:797-804.
4. Mann CJ, Yen FT, Grant AM, Bihain BE. Mechanism of plasma cholesteryl ester transfer in hypertriglyceridemia. J Clin Invest. 1991;88:2059-2066.
5. Morton RE. Free cholesterol is a potent regulator of lipid transfer protein function. J Biol Chem. 1988;263:12235-12241.
6. Bagdade JD, Ritter MC, Subbaiah PV. Accelerated cholesteryl ester transfer in plasma of patients with hypercholesterolemia. J Clin Invest. 1991;87:1259-1265.
7. Morton RE, Parks JS. Plasma cholesteryl transfer protein activity is modulated by the phase transition of the lipoprotein core. J Lipid Res. 1996;37:1915-1923.
8. Bruce C, Davidson WS, Kussie P, Lund-Katz S, Phillips MC, Ghosh R, Tall AR. Molecular determinants of plasma cholesteryl ester transfer protein binding to high density lipoproteins. J Biol Chem. 1995;270:11532-11542.
9. Morton RE, Greene DJ. Regulation of lipid transfer between lipoproteins by an endogenous plasma protein: selective inhibition among lipoprotein classes. J Lipid Res. 1994;35:836-847.
10. Morton RE. Binding of plasma-derived lipid transfer protein to lipoprotein substrates: the role of binding in the lipid transfer process. J Biol Chem. 1985;260:12593-12599.
11. Nishide T, Tollefson JH, Albers JJ. Inhibition of lipid transfer by a unique high density lipoprotein subclass "containing an inhibitor protein. J Lipid Res. 1989;30:149-158.
12. Wang S, Kussie P, Deng L, Tall A. Defective binding of neutral lipids by a carboxyl-terminal deletion mutant of cholesteryl ester transfer protein: evidence for a carboxyl-terminal cholesteryl ester binding site essential for neutral lipid transfer activity. J Biol Chem. 1995;270:612-618.
13. Pattnaik NM, Zilversmit DB. Interaction of cholesteryl ester exchange protein with human plasma lipoproteins and phospholipid vesicles. J Biol Chem. 1979;254:2782-2786.
14. Nishida HI, Arai H, Nishida T. Cholesterol ester transfer mediated by lipid transfer protein as influenced by changes in the charge characteristics of plasma lipoproteins. J Biol Chem. 1993;268:16352-16360.
15. Tall A, Sammett D, Granot E. Mechanisms of enhanced cholesteryl ester transfer from high density lipoproteins to apolipoprotein B-containing lipoproteins during alimentary lipemia. J Clin Invest. 1986;77:1163-1172.