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Volumn 99, Issue 4, 1997, Pages 756-765

Redox regulation of apoptosis in interleukin-3-dependent haemopoietic cells: Absence of alteration in both mitochondrial membrane potential (Δψ(m) and free radical production during apoptosis induced by IL3 withdrawal

Author keywords

Apoptosis; Cell cycle; Cell shape; Free radicals; Mitochondria

Indexed keywords

DNA FRAGMENT; FREE RADICAL; GLUTATHIONE; INTERLEUKIN 3; LACTIC ACID;

EID: 0031459451     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.4733277.x     Document Type: Article
Times cited : (9)

References (48)
  • 1
    • 0017865443 scopus 로고
    • Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates
    • Babson, J.R. & Reed, D.J. (1978) Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates. Biochemical and Biophysical Research Communications, 83, 754-762.
    • (1978) Biochemical and Biophysical Research Communications , vol.83 , pp. 754-762
    • Babson, J.R.1    Reed, D.J.2
  • 2
    • 0027523461 scopus 로고
    • Apoptosis induced by withdrawal of interleukin 3 (IL3) from an IL3-dependent hemopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production
    • Baffy, G., Miyashita, T., Williamson, J.R. & Reed, J.C. (1993) Apoptosis induced by withdrawal of interleukin 3 (IL3) from an IL3-dependent hemopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production. Journal of Biological Chemistry, 268, 6511-6519.
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 6511-6519
    • Baffy, G.1    Miyashita, T.2    Williamson, J.R.3    Reed, J.C.4
  • 3
    • 0028362316 scopus 로고
    • Contribution of hypoxia-reperfusion injury to inflammatory synovitis: Influence of reactive oxygen intermediates on the transcriptional control of inflammation
    • Blake, D.R., Winyard, P.G. & Marok, R. (1994) Contribution of hypoxia-reperfusion injury to inflammatory synovitis: influence of reactive oxygen intermediates on the transcriptional control of inflammation. Annals of the New York Academy of Sciences, 723, 308-317.
    • (1994) Annals of the New York Academy of Sciences , vol.723 , pp. 308-317
    • Blake, D.R.1    Winyard, P.G.2    Marok, R.3
  • 4
    • 0025994294 scopus 로고
    • Repair of DNA damage induced by reactive-oxygen species
    • Briemar, L.H. (1991) Repair of DNA damage induced by reactive-oxygen species. Free Radical Research Communications, 14, 159-171.
    • (1991) Free Radical Research Communications , vol.14 , pp. 159-171
    • Briemar, L.H.1
  • 5
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • Chance, B., Seis, H. & Boveris, A. (1979) Hydroperoxide metabolism in mammalian organs. Physiological Reviews, 59, 527-605.
    • (1979) Physiological Reviews , vol.59 , pp. 527-605
    • Chance, B.1    Seis, H.2    Boveris, A.3
  • 6
    • 0018368359 scopus 로고
    • Role of glutathione and glutathione S-transferases in the metabolism of chemical carcinogens and other electrophilic agents
    • Chasseaud, L.F. (1979) Role of glutathione and glutathione S-transferases in the metabolism of chemical carcinogens and other electrophilic agents. Advances in Cancer Research, 29, 175-274.
    • (1979) Advances in Cancer Research , vol.29 , pp. 175-274
    • Chasseaud, L.F.1
  • 7
    • 0026731894 scopus 로고
    • Interleukin 3 protects murine bone marrow cells from apoptosis by DNA damaging agents
    • Collins, M., Marvel, J., Malde, P. & Lopez-Rivas, A. (1992) Interleukin 3 protects murine bone marrow cells from apoptosis by DNA damaging agents. Journal of Experimental Medicine, 176, 1043-1051.
    • (1992) Journal of Experimental Medicine , vol.176 , pp. 1043-1051
    • Collins, M.1    Marvel, J.2    Malde, P.3    Lopez-Rivas, A.4
  • 9
    • 0031054903 scopus 로고    scopus 로고
    • Energy metabolism during apoptosis: bcl-2 promotes survival in hemopoietic cells induced to apoptose by growth factor withdrawal by stabilising a form of metabolic arrest
    • Garland, J.M. & Halestrap, A. (1997) Energy metabolism during apoptosis: bcl-2 promotes survival in hemopoietic cells induced to apoptose by growth factor withdrawal by stabilising a form of metabolic arrest. Journal of Biological Chemistry, 272, 4680-4688.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 4680-4688
    • Garland, J.M.1    Halestrap, A.2
  • 10
    • 0023729127 scopus 로고
    • Cell stimulation by interleukin 3 is a novel process of signal transduction: The rolling cell cycle and its implications for leukemic transformation
    • Garland, J.M., Kinnaird, A. & Elliott. K. (1942) Cell stimulation by interleukin 3 is a novel process of signal transduction: the rolling cell cycle and its implications for leukemic transformation. Leukemia, 2, 476-480.
    • (1942) Leukemia , vol.2 , pp. 476-480
    • Garland, J.M.1    Kinnaird, A.2    Elliott, K.3
  • 11
    • 6844251408 scopus 로고    scopus 로고
    • Cytochrome C induces apoptosis in intact cells and is dominant to growth signalling, apoptosis suppression and malignant change
    • in press
    • Garland, J.M. & Rudin, C. (1997) Cytochrome C induces apoptosis in intact cells and is dominant to growth signalling, apoptosis suppression and malignant change. Blood (in press).
    • (1997) Blood
    • Garland, J.M.1    Rudin, C.2
  • 12
    • 0027765905 scopus 로고
    • Free radicals in disease processes: A compilation of cause and consequence
    • Gutteridge, J.M. (1993) Free radicals in disease processes: a compilation of cause and consequence. Free Radical Research Communications, 19, 41-158.
    • (1993) Free Radical Research Communications , vol.19 , pp. 41-158
    • Gutteridge, J.M.1
  • 13
    • 0028068186 scopus 로고
    • Free radicals, antioxidants and human disease: Curiosity, cause or consequence?
    • Halliwell, B. (1994) Free radicals, antioxidants and human disease: curiosity, cause or consequence? Lancet, 344, 721-724.
    • (1994) Lancet , vol.344 , pp. 721-724
    • Halliwell, B.1
  • 15
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery, D., Nunez, G., Millison, C., Schrieber, R.D. & Korsmeyer, S.J. (1993a) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature, 348, 334-336.
    • (1993) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Millison, C.3    Schrieber, R.D.4    Korsmeyer, S.J.5
  • 16
    • 0027485461 scopus 로고
    • Bcl-2 functions in an antioxidant pathway to prevent apoptosis
    • Hockenbery, D., Oltvai, Z.N., Yin, X., Milliman, C.I., & Korsmeyer, S. (1993b) Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell, 75, 241-251.
    • (1993) Cell , vol.75 , pp. 241-251
    • Hockenbery, D.1    Oltvai, Z.N.2    Yin, X.3    Milliman, C.I.4    Korsmeyer, S.5
  • 17
    • 0027311843 scopus 로고
    • Visualization of replicative factories attached to the nucleoskeleton
    • Hozak, P., Hassian, A.R., Jackson, D.A. & Cook, P.R. (1993) Visualization of replicative factories attached to the nucleoskeleton. Cell, 73, 361-373.
    • (1993) Cell , vol.73 , pp. 361-373
    • Hozak, P.1    Hassian, A.R.2    Jackson, D.A.3    Cook, P.R.4
  • 18
    • 0028845212 scopus 로고
    • Cytoknie receptor signalling
    • Ihle, J.N. (1995) Cytoknie receptor signalling. Nature, 377, 591-593.
    • (1995) Nature , vol.377 , pp. 591-593
    • Ihle, J.N.1
  • 19
    • 0030046753 scopus 로고    scopus 로고
    • STATs: Signal transducers and activators of transcription
    • Ihle, J.N. (1996) STATs: signal transducers and activators of transcription. Cell, 84, 331-335.
    • (1996) Cell , vol.84 , pp. 331-335
    • Ihle, J.N.1
  • 20
    • 0029887634 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signalling
    • Itoh, T., Muto, A., Watenabe, S., Miyajima, A., Yokota, T. & Arai, K. (1996) Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signalling. Journal of Biological Chemistry, 271, 7587-7592.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 7587-7592
    • Itoh, T.1    Muto, A.2    Watenabe, S.3    Miyajima, A.4    Yokota, T.5    Arai, K.6
  • 21
    • 0028939139 scopus 로고
    • Programmed cell death and bcl-2 protection in very low oxygen
    • Jacobson, M.D. & Raff, M.C. (1995) Programmed cell death and bcl-2 protection in very low oxygen. Nature, 374, 814-816.
    • (1995) Nature , vol.374 , pp. 814-816
    • Jacobson, M.D.1    Raff, M.C.2
  • 22
    • 0027717968 scopus 로고
    • Bcl-2 inhibits neuronal death: Decreased generation of reactive oxygen species
    • Kane, D.J., Sarafian, T.A., Anton, R., Hahn, N., Gralla, E.B., Ord, T. & Bredesen, D.E. (1993) Bcl-2 inhibits neuronal death: decreased generation of reactive oxygen species. Science, 262, 1274-1277.
    • (1993) Science , vol.262 , pp. 1274-1277
    • Kane, D.J.1    Sarafian, T.A.2    Anton, R.3    Hahn, N.4    Gralla, E.B.5    Ord, T.6    Bredesen, D.E.7
  • 23
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for bcl-2 regulation of apoptosis
    • Kluck, R.M., Bossy-Wetzel, E., Green, D. & Newmeyer, D.D. (1997) The release of cytochrome c from mitochondria: a primary site for bcl-2 regulation of apoptosis. Science, 275, 1132-1136.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.3    Newmeyer, D.D.4
  • 24
    • 0026554428 scopus 로고
    • Evaluation of the probe 2′7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress
    • LeBel, C.P., Ischiropoulos, H. & Bondy, S.C. (1992) Evaluation of the probe 2′7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chemical Research in Toxicology. 5, 227-231.
    • (1992) Chemical Research in Toxicology , vol.5 , pp. 227-231
    • LeBel, C.P.1    Ischiropoulos, H.2    Bondy, S.C.3
  • 25
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-tree extracts: Requirement for dATP and cytochrome c
    • Liu, X., Kim, C.N., Yang, J., Jemmerson, R. & Wang, X. (1996) Induction of apoptotic program in cell-tree extracts: requirement for dATP and cytochrome c. Cell, 86, 147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 27
    • 0020537304 scopus 로고
    • Selective modification of glutathione metabolism
    • Meister, A. (1983) Selective modification of glutathione metabolism. Science, 220, 472-477.
    • (1983) Science , vol.220 , pp. 472-477
    • Meister, A.1
  • 30
    • 0019470352 scopus 로고
    • Tumour cell anti-oxidant defences: Inhibition of the glutathione redox cycle enhances macrophage-mediated cytolysis
    • Nathan, C.F., Arrick, B.A. Murray, H.W., DeSantis, N.M. & Cohn, Z.A. (1981) Tumour cell anti-oxidant defences: inhibition of the glutathione redox cycle enhances macrophage-mediated cytolysis. Journal of Experimental Medicine, 153, 766-782.
    • (1981) Journal of Experimental Medicine , vol.153 , pp. 766-782
    • Nathan, C.F.1    Arrick, B.A.2    Murray, H.W.3    DeSantis, N.M.4    Cohn, Z.A.5
  • 31
    • 0028019746 scopus 로고
    • Cell-free apoptosis in Xenopus egg extracts: Inhibition by bcl-2 and requirement for an organelle fraction enriched in mitochondria
    • Newmeyer, D.D., Farschon, D.M. & Reed, J.C. (1994) Cell-free apoptosis in Xenopus egg extracts: inhibition by bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell, 79, 353-364.
    • (1994) Cell , vol.79 , pp. 353-364
    • Newmeyer, D.D.1    Farschon, D.M.2    Reed, J.C.3
  • 32
    • 78651196288 scopus 로고
    • A colourimetric micro method for the detection of glutathione
    • Owens, C.W. & Belcher, R.V. (1965) A colourimetric micro method for the detection of glutathione. Biochemical Journal, 94, 705-711.
    • (1965) Biochemical Journal , vol.94 , pp. 705-711
    • Owens, C.W.1    Belcher, R.V.2
  • 33
    • 0021325167 scopus 로고
    • Distinct mechanisms may account for the growth promoting effects of interleukin 3 on cells of lymphoid and myeloid lineage
    • Palacios, R. & Garland, J.M. (1984) Distinct mechanisms may account for the growth promoting effects of interleukin 3 on cells of lymphoid and myeloid lineage. Proceedings of the National Academy of Sciences of the United States of America, 81, 1208-1211.
    • (1984) Proceedings of the National Academy of Sciences of the United States of America , vol.81 , pp. 1208-1211
    • Palacios, R.1    Garland, J.M.2
  • 34
    • 0029874495 scopus 로고    scopus 로고
    • The role of MAP kinase kinase in Interleukin 3 stimulation of proliferation
    • Perkins, G.R., Marshall, C.J. & Collins, M. (1996) The role of MAP kinase kinase in Interleukin 3 stimulation of proliferation. Blood, 87, 3669-3675.
    • (1996) Blood , vol.87 , pp. 3669-3675
    • Perkins, G.R.1    Marshall, C.J.2    Collins, M.3
  • 35
    • 0025690822 scopus 로고
    • Analysis of the membrane potential of rat- and mouse-liver mitochondria by flow cytometry and possible applications
    • Petit, P.X., O'Connor, J.E., Grunwald, D. & Brown, S.C. (1990) Analysis of the membrane potential of rat- and mouse-liver mitochondria by flow cytometry and possible applications. European Journal of Biochemistry, 194, 389-397.
    • (1990) European Journal of Biochemistry , vol.194 , pp. 389-397
    • Petit, P.X.1    O'Connor, J.E.2    Grunwald, D.3    Brown, S.C.4
  • 36
    • 0023925454 scopus 로고
    • Interactions between deoxyribonucleotide and DNA synthesis
    • Reichard. P. (1980) Interactions between deoxyribonucleotide and DNA synthesis. Annual Review of Biochemistry, 57, 349-374.
    • (1980) Annual Review of Biochemistry , vol.57 , pp. 349-374
    • Reichard, P.1
  • 37
    • 0027494821 scopus 로고
    • Signal transduction by the high-affinity GM-CSF receptor: Two distinct cytoplasmic regions of the common beta subunit responsible for different signalling
    • Sato, N., Sakamaki, K., Terada, N., Arai, K. & Miyajima, A. (1993) Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signalling. EMBO Journal, 12, 4181-4189.
    • (1993) EMBO Journal , vol.12 , pp. 4181-4189
    • Sato, N.1    Sakamaki, K.2    Terada, N.3    Arai, K.4    Miyajima, A.5
  • 38
    • 0026970404 scopus 로고
    • Nuclear factor kappa B: An oxidative stress-response transcription factor of eukaryotic cells
    • Schreck, R., Albermann, K. & Baeuerle, P.A. (1992) Nuclear factor kappa B: an oxidative stress-response transcription factor of eukaryotic cells. Free Radicals Research Communications, 17, 221-237.
    • (1992) Free Radicals Research Communications , vol.17 , pp. 221-237
    • Schreck, R.1    Albermann, K.2    Baeuerle, P.A.3
  • 43
    • 0028068607 scopus 로고
    • Interleukin (IL) 3 and granulocyte/macrophage colony-stimulating factor, but not IL4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3′ kinase
    • Welham, M.J., Dechert, U., Leslie, K.B., Jirik, F. & Schrader, J. (1994) Interleukin (IL) 3 and granulocyte/macrophage colony-stimulating factor, but not IL4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3′ kinase. Journal of Biological Chemistry, 269, 23764-23768.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 23764-23768
    • Welham, M.J.1    Dechert, U.2    Leslie, K.B.3    Jirik, F.4    Schrader, J.5
  • 44
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by bcl-2: Release of cytochrome c from mitochondria blocked
    • Yang, J., Liu, X., Bhalla, K., Kim, C., Ibrado, A., Cai, J., Peng, T-I., Jones, D. & Wang, X. (1997) Prevention of apoptosis by bcl-2: release of cytochrome c from mitochondria blocked. Science, 275, 1129-1132.
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.4    Ibrado, A.5    Cai, J.6    Peng, T.-I.7    Jones, D.8    Wang, X.9
  • 45
    • 0010471495 scopus 로고
    • Cellular defences against damage from reactive oxygen species
    • Yu, B.P. (1994) Cellular defences against damage from reactive oxygen species. Physiological Reviews, 74, 139-162.
    • (1994) Physiological Reviews , vol.74 , pp. 139-162
    • Yu, B.P.1
  • 47
    • 0029983059 scopus 로고    scopus 로고
    • Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis
    • Zamzami, N., Marchetti, P., Castedo, M., Hirsch, T., Susin, S.A., Masse, B. & Kroemer, G. (1996) Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis. FEBS Letters, 384, 53-57.
    • (1996) FEBS Letters , vol.384 , pp. 53-57
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3    Hirsch, T.4    Susin, S.A.5    Masse, B.6    Kroemer, G.7


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