Thrombin stimulates syndecan-1 promotor activity and expression of a form of syndecan-1 that binds antithrombin III in vascular smooth muscle cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 11, 1997, Pages 2609-2616

  Cizmeci Smith, Gunay ^a   Carey, David J ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Antithrombin III; Heparan sulfate proteoglycans; Smooth muscle cells; Syndecan; Thrombin

Indexed keywords

ANTITHROMBIN III; CALCIUM ION; HERBIMYCIN A; MESSENGER RNA; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; PROTEOGLYCAN; SYNDECAN; THROMBIN; THROMBIN INHIBITOR;

ANIMAL CELL; ANTICOAGULATION; ARTICLE; BLOOD VESSEL INJURY; CONTROLLED STUDY; ENZYME ACTIVITY; FEEDBACK SYSTEM; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INDUCTION; RAT; THROMBUS; TRANSCRIPTION REGULATION; VASCULAR SMOOTH MUSCLE;

EID: 0031459408     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.11.2609     Document Type: Article

References (28)

1. Bernfield M, Kokenyesi R, Kato M, et al. The biology of the syndecans. Annu Rev Cell Biol. 1992;8:365-393.
2. Rapraeger AC. The coordinated regulation of heparan sulfate, syndecans and cell behavior. Curr Opin Cell Biol. 1993;5:844-953.
3. Asundi V, Cowan K, Matzura D, Wagner W, Dreher KL. Characterization of extracellular matrix proteoglycan transcripts expressed by vascular smooth muscle cells. European Journal of Cell Biology. 1990;52:98-104.
4. Kjellen L, Lindahl U. Proteoglycans: structures and interactions. Annu Rev Biochem. 1991;60:443-475.
5. Cizmeci-Smith G, Asundi VK, Stahl RC, et al. Regulated expression of syndecan in vascular smooth muscle cells and cloning of rat syndecan core protein cDNA. J Biol Chem. 1992;267:15729-15736.
6. Kojima T, Shworak NW, Rosenberg RD. Molecular cloning and expression of two distinct cDNA-encoding heparan sulfate proteoglycan core proteins from a rat endothelial cell line. J Biol Chem. 1992;267:4870-4877.
7. Cizmeci-Smith G, Stahl RC, Showalter LJ, Carey DJ. Differential expression of transmembrane proteoglycans in vascular smooth muscle cells. J Biol Chem. 1993;268:18740-18747.
8. Cizmeci-Smith G, Langan E, Youkey J, Showalter LJ, Carey DJ. Syndecan-4 is a primary response gene induced by bFGF and arterial injury in vascular smooth muscle cells. Art Throm Vasc Biol. 1997;17:172-180.
9. McNamara CA, Sarembock IJ, Gimple LW, Fenton JW, Coughlin SR, Owens GK. Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor. J Clin Invest. 1993;91:94-98.
10. Berk EC, Taubman MB, Griendling KK, Cragoe EJJ, Fenton JW, Brock TA. Thrombin-stimulated events in cultured vascular smooth-muscle cells. Biochem J. 1991;274:799-805.
11. Rosenberg RD, Damus PS. The purfication and mechanism of action of human antitrombin-heparin cofactor. J Biol Chem. 1973;248:6490-6505.
12. Kojima T, Leone C, Marchildon G, Marcum J, Rosenberg R. Isolation and characterization of heparan sulfate proteoglycans produced by cloned rat microvascular endothelial cells. J Biol Chem. 1992;267:4859-4869.
13. Hinkes MT, Goldberger OA, Neumann PE, Kokenyesi R, Bernfield M. Organization and promoter activity of the mouse syndecan-1 gene. J Biol Chem. 1993;268:11440-11448.
14. Vihinen T, Auvinen P, Alanen-Kurki L, Jalkanen M. Structural organization and genomic sequence of mouse syndecan-1 gene. J Biol Chem. 1993;268:17261-17269.
15. Hamati HF, Britton EL, Carey DJ. Inhibition of proteoglycan synthesis alters extracellular matrix deposition, proliferation, and cytoskeletal organization of rat aortic smooth muscle cells in culture. J Cell Biol. 1989;108:2495-2505.
16. Scarpati E, DiCorleto PE. Identification of a thrombin response element in the human platelet-derived growth factor B-chain 9c-sis promoter. J Biol Chem. 1996;271:3025-3032.
17. Vihinen T, Maata A, Jaakkola P, Auvinen P, Jalkanen M. Functional characterization of mouse syndecan-1 promoter. J Biol Chem. 1996;172:12532-12541.
18. Herschman HR. Primary response genes induced by growth factors and tumor promoters. Annu Rev Biochem. 1991;60:281-319.
19. Zhong C, Hayzer DJ, Corson MA, Runge MS. Molecular cloning of the rat vascular smooth muscle thrombin receptor: evidence for in vitro regulation by basic fibroblast growth factor. J Biol Chem. 1992;267:16975-16979.
20. Hung DT, Vu TH, Nelken NA, Coughlin SR. Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor. J Cell Biol. 1992;116:827-832.
21. Stouffer GA, Sarembock IJ, McNamara CA, Gimple LW, Owens GK. Thrombin-induced mitogenesis of vascular SMC is partially mediated by autocrine production of PDGF-AA. Amer J Physiol. 1993;265:C806-C811.
22. Weiss RH, Maduri M. The mitogenic effect of thrombin in vascular smooth muscle cells is largely due to basic fibroblast growth factor. J Biol Chem. 1993;268:5724-5727.
23. syk to the cytoskeleton in thrombin-stimulated platelets. J Biol Chem. 1994;269:32796-32799.
24. Carey DJ, Stahl RC, Cizmeci-Smith G, Asundi VK. Syndecan-1 expressed in Schwann cells causes morphological transformation and cytoskeletal reorganization and associates with actin during cell spreading. J Cell Biol. 1994;124:161-170.
25. Weiss RH, Nuccitelli R. Inhibition of tyrosine phosphorylation prevents thrombin-induced mitogenesis, but not intracellular free calcium release, in vascular smooth muscle cells. J Biol Chem. 1992;267:5608-5613.
26. Berk BC, Taubman MB, Cragoe EJ, Jr, Fenton JW II, Griendling KK. Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. J Biol Chem. 1990;265:17334-17340.
27. Shworak NW, Shirakawa M, Mulligan RC, Rosenberg RD. Characterization of ryudocan glycosaminoglycan acceptor sites. J Biol Chem. 1994;269:21204-21214.
28. deAgostini AI, Watkins SC, Slayter HS, Youssoufian H, Rosenberg RD. Localization of anticoagulantly active heparan sulfate proteoglycans in vascular endothelium: antithrombin binding on cultured endothelial cells and perfused rat aorta. J Cell Biol. 1995;111:1293-1304.