Synthesis of cytotoxic 1-polyhydroxyalkyl-β-carboline derivatives

European Journal of Medicinal Chemistry

Volumn 32, Issue 12, 1998, Pages 1009-1017

  Abdel Moty, S G ^a   Sakai, S ^a   Aimi, N ^a   Takayama, H ^a   Kitajima, M ^a   El Shorbagi, A ^b   Ahmed, A N ^b   Omar, N M ^b  

^a CHIBA UNIVERSITY   (Japan)

^b Assiut University   (Egypt)

Author keywords

Cytotoxic activity; N9 benzyl and N9 methyl derivatives; Polyhydroxyalkyl derivatives; Stereoselective synthesis; Wittig reaction; carboline alkaloids

Indexed keywords

BETA CARBOLINE DERIVATIVE;

ARTICLE; CELL CULTURE; CELL STRAIN HL 60; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; FETUS LUNG; FIBROBLAST; IN VITRO STUDY; LUNG FIBROBLAST; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROMYELOCYTIC LEUKEMIA; TUMOR CELL; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0031459366     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(97)89645-6     Document Type: Article

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