Functional characterization of an endogenous digitalis-like factor in human newborn plasma. Effects on rat (Na+/K+)-ATPase isoforms and on binding to placenta

Annals of the New York Academy of Sciences

Volumn 834, Issue , 1997, Pages 621-625

  Crambert, G ^a   Balzan, S ^b   Paci, A ^b   Decollogne, S ^a   Montali, U ^c   Ghione, S ^b   Lelievre L G ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^c UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE INHIBITOR; CARDIAC GLYCOSIDE; DIGITALIS LIKE FACTOR; ISOENZYME;

ANIMAL TISSUE; BINDING COMPETITION; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME INHIBITION; NONHUMAN; PLACENTA; PLASMA; RAT;

ANIMALIA; DIGITALIS;

EID: 0031459363     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb52332.x     Document Type: Conference Paper

References (13)

1. GOTO, A., K. YAMADA, N. YAGI, M. YOSHIOKA & T. SUGIMOTO. 1992. Physiology and pharmacology of endogenous digitalis-like factors. Pharmacol. Rev. 44: 377-399.
2. HAMLYN, J. M. 1994. Ouabain: An endogenous mammalian ligand for the sodium pump. DuPont NEN Biotech Update. 9: 16-18.
3. +-ATPase. Biochim. Biophys. Acta 988: 185-220.
4. BALZAN, S., S. GHIONE, P. BIVER, P. GAZZETTI & U. MONTALI. 1991. Partial purification of endogenous digitalis-like compound(s) in cord blood. Clin. Chem. 37: 277-281.
5. MONTALI, U., S. BALZAN & S. GHIONE. 1991. Purification of endogenous digitalis-like factor(s) from cord blood of neonate by immunoaffinity chromatography. Biochem. Int. 25: 853-859.
6. BERREBI-BERTRAND, I., J. M. MAIXENT, G. CHRISTE & L. G. LELIÈVRE. 1990. Two active N/K-ATPase of high affinity for ouabain in adult rat brain membranes. Biochim. Biophys. Acta 1021: 148-156.
7. SWEADNER, K. J. 1979. Two molecular forms of (Na + K) stimulated ATPase in the brain: Separation and difference in affinity for strophanthidin. J. Biol. Chem. 254: 6060-6067.
8. MANSIER, P., D. CHARLEMAGNE, B. Rossi, M. PRETESEILLE, B. SWYNGHEDAW & L. LELIÈVRE. 1983. Isolation of impermeable inside-out vesicles from an enriched sarcolemma fraction of rat heart. J. Biol. Chem. 258: 6628-6635.
9. LELIÈVRE, L. G., P. LORENTE, J. M. MAIXENT, C. MOUAS & B. SWYNGHEDAUW. 1986. Prolonged responsiveness to ouabain in hypertrophied rat heart. Physiological and biochemical studies. Am. J. Physiol. 251: H923-H931.
10. PACI, A., F. COCCI, F. PIRAS, G. CIARIMBOLI & A. CLERICO. 1989. Specific binding of cardiac glycoside drugs and endogenous digitalis-like substances to particulate membrane fractions from human placenta. Clin. Chem. 35: 2093-2097.
11. PACI, A., G. CIARIMBOLI & P. BIVER. 1996. Human placenta radioreceptor assay with digoxin and ouabain to detect endogenous digitalis-like factor(s) in human plasma and urine. Clin. Chem. 42: 270-278.
12. +)ATPase in myocytes from adult rat heart. J. Biol. Chem. 262: 8941-8943.
13. +)-ATPase activity highly sensitive to ouabain. Nature 300: 535-537.