Pharmacological management of neonatal opioid abstinence syndrome

CNS Drugs

Volumn 8, Issue 6, 1997, Pages 448-456

  Nair, Prasanna ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; COCAINE; DIAMORPHINE; METHADONE; MORPHINE DERIVATIVE; OPIATE AGONIST; PAREGORIC; PHENOBARBITAL; SPASMOLYTIC AGENT;

ABSTINENCE; ADULT; CHILD ABUSE; CLINICAL FEATURE; DEHYDRATION; DIARRHEA; DISEASE SEVERITY; DRUG WITHDRAWAL; ELECTROLYTE DISTURBANCE; FEMALE; FETUS; FOSTER CARE; HIGH RISK POPULATION; HUMAN; NEWBORN DISEASE; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RESPIRATORY ALKALOSIS; REVIEW; SEIZURE; SUBSTANCE ABUSE; VOMITING;

EID: 0031459017     PISSN: 11727047     EISSN: None     Source Type: Journal    
DOI: 10.2165/00023210-199708060-00003     Document Type: Review

References (70)

1. National Institute on Drug Abuse. The national pregnancy and health survey by NIDA: drug use among women delivering live births in 1992. Rockville (MD): NIH Publication, 1916: 96-3819
2. Perez-Beseos L, Arrate-Zugazabeitia JK, Fortea-Jimeno E, et al. The clinical and epidemiological aspects of the neonatal abstinence syndrome [in Spanish]. Bol Med Hosp Infant Mex 1993; 50 (12): 843-8
3. Swift W, Copeland J, Hall W. Characteristics of women with alcohol and other drug problems: findings of an Australian national survey. Addiction 1996; 91 (8): 1141-50
4. Mangweth B, Pope Jr HG, Ionescu-Pioggia M, et al. Drug use and lifestyle among college students in Austria and the United States. Subst Use Misuse 1997; 32 (4): 461-73
5. Knolle H. Dynamics of the drug scene in Switzerland 1977-1990. Soz Praventivmed 1996; 41 (3): 143-9
6. Wai H, Young D, Lingjiang L, et al. Psychoactive substance use in three sites in China: gender differences and related factors. Addiction 1995; 90 (11): 1503-15
7. Hafeiz HB. Socio-demographic correlates and patterns of drug abuse in eastern Saudi Arabia. Drug Alcohol Depend 1995; 38 (3): 255-9
8. Madianos MG, Gefou-Madianou D, Stefanis CN. Drinking practices of illicit and licit drug users in the general population across Greece. Am J Drug Alcohol Abuse 1994; 20 (4): 547-59
9. Chasnoff IJ, Hatcher R, Burns WJ. Polydrug- and methadone-addicted newborns: a continuum of impairment? Pediatrics 1982 Aug; 70 (2): 210-3
10. Berlin CM. Effects of drugs on the fetus. Pediatrics Rev 1991; 12 (9): 282-7
11. Brown E, Zuckerman B. The infant of the drug-abusing mother. Ann Pediatrics 1991; 20: 555-63
12. Chiriboga CA. Fetal effects. Neurol Clin 1993 Aug; 11 (3): 707-28
13. Davidson Ward SL, Bautista D, Chan L, et al. Sudden infant death syndrome in infants of substance-abusing mothers. J Pediatr 1990 Dec; 117 (6): 876-81
14. DeCubas MM, Field T. Children of methadone-dependent women: developmental outcomes. Am J Orthopsych 1993 Apr; 63 (2): 266-76
15. Fricker HS, Segal S. Narcotic addiction, pregnancy, and the newborn. Am J Dis Child 1978 Apr; 132: 360-6
16. Fulroth R, Phillips B, Durand DJ. Perinatal outcome of infant exposed to cocaine and/or heroin in utero. Am J Dis Child 1989; 143: 905-10
17. Little BB, Snell LM, Klein VR. Maternal and fetal effects of heroin addiction during pregnancy. J Reprod Med 1990 Feb; 35 (2): 159-62
18. Lam SK, To WK, Duthie SJ, et al. Narcotic addiction in pregnancy with adverse maternal and perinatal outcome. Aust NZ J Obstet Gynaecol 1992; 32 (3): 216-21
19. Ostrea EM, Chavez CJ. Perinatal problems (excluding neonatal withdrawal) in maternal drug addiction: a study of 830 cases. J Pediatr 1979; 94: 292-5
20. Zuckerman B, Frank DA, Hingson R, et al. Effects of maternal marijuana and cocaine use on fetal growth. N Engl J Med 1989; 320 (12): 762-8
21. Black MM, Nair P, Schuler M. Prenatal drug exposure: neurodevelopmental outcome and parenting environment. J Pediatr Psychol 1993; 18: 605-20
22. Fundaro C, Solinas A, Martino AM, et al. Sindrome d'astinenza neonatale e profilo tossicologica materno. Minerva Pediatr 1994; 46 (3): 83-8
23. Anand KJ, Arnold JH. Opioid tolerance and dependence in infants and children. Crit Care Med 1994 Feb; 22 (2): 334-42
24. Eisenberg RM. Short-term tolerance to morphine: effects of indomethacin. Life Sci 1982; 30: 1399-405
25. Dewey WL. Various factors which affect the rate of development of tolerance and physical dependence to abused drugs. NIDA Res Monogr 1984; 54: 39-49
26. Gomby DS, Shiono PH. Estimating the numbers of substance exposed infants. Future Child 1991; 1: 17-25
27. Wheeler SF. Substance abuse during pregnancy. Prim Care 1993 Mar; 20 (1): 191-207
28. Zuckerman B, Frank D, Hingson R, et al. The validity of self-reported marijuana and cocaine use among pregnant adolescents. J Pediatr 1989; 115: 812-5
29. Chavkin W, Kandall SR. Between a 'rock' and a hard place: perinatal drug abuse. Pediatrics 1990; 85 (2): 223-5
30. Halstead AC, Godolphin W, Lockitch G, et al. Timing of specimen collection is crucial in urine screening of drug dependent mothers and newborns. Clin Biochem 1988; 21: 59-61
31. Callahan CM, Grant TM, Phipps P, et al. Measurement of gestational cocaine exposure: sensitivity of infant's hair, meconium, and urine. J Pediatr 1992; 120: 763-8
32. Ostrea EM, Parks PM, Brady MJ. Rapid isolation and detection of drugs in meconium of infants of drug-dependent mothers. Clin Chem 1988; 34 (11): 2372-3
33. Ostrea EM, Brady MJ, Parks PM, et al. Drug screening of meconium in infants of drug-dependent mothers: an alternative to urine testing. J Pediatr 1989; 115 (3): 474-7
34. Ostrea EM, Brady M, Gause S, et al. Drug screening of newborns by meconium analysis: a large-scale, prospective, epidemiologic study. Pediatrics 1992; 89 (1): 107-13
35. Nair P, Rothhlum B, Hebel R. Neonatal outcome of infants with evidence of fetal exposure to opiates, cocaine, and cannabinoids. Clin Pediatr 1994 May; 33 (5): 280-5
36. Baumgartner A, Jones P, Baumgartner W, et al. Radioimmunoassay of hair for determining opiate abuse histories. J Nucl Med 1979; 2: 748-52
37. Graham K, Koren G, Klien J, et al. Determination of gestational cocaine exposure by hair analysis. JAMA 1989; 262: 3328-30
38. Finnegan LP. Effects of maternal opiate abuse on the newborn. Fed Proc 1985; 44: 2314-7
39. Chasnoff IJ. Newborn infants with drug withdrawal symptoms. Pediatr Rev 1988 Mar; 9 (9): 273-7
40. Harper RG, Solish G, Feinhgold E, et al. Maternal ingested methadone, body fluid methadone, and the neonatal withdrawal syndrome. Am J Obstet Gynecol 1977 Oct; 129: 417-24
41. Maas U, Kattner E, Weingart-Jesse B, et al. Infrequent neonatal opiate withdrawal following maternal methadone detoxification during pregnancy. J Perinat Med 1989; 18: 111-8
42. Mack G, Thomas D, Giles W, et al. Methadone levels and neonatal withdrawal. J Paediatr Child Health 1991; 27: 96-100
43. Shaw MJ, McIvor L. Neonatal abstinence syndrome after maternal methadone treatment. Arch Dis Child 1994; 71: F203-5
44. Trujillo KA, Akil H. Opiate tolerance and dependence: recent findings and synthesis. New Biol 1991; 3: 915-23
45. Arnold JH, Truog RD, Orav EJ, et al. Tolerance and dependence in neonates sedated with fentanyl during extracorporeal membrane oxygenation. Anesthesiology 1990; 73: 1136-40
46. Bell GL, Lau K. Perinatal and neonatal issues of substance abuse. Pediatr Clin North Am 1995 Apr; 42 (2): 261-81
47. Eaton DG, Wertheim D, Oozeer R, et al. The effect of pethidine on the neonatal EEG. Dev Med Child Neurol 1992; 34: 155-63
48. Anwar M, Garrettson L, Huddleston K, et al. Withdrawal seizures in a neonate following prolonged fentanyl use [abstract]. J Toxicol Clin Toxicol 1995 Sept; 33: 493
49. Rodning C, Beckwith L, Howard J. Prenatal exposure to drugs: behavioral distortions reflecting CNS impairment? Neurotoxicology 1989; 10: 629-34
50. Doberczak TM, Kandall SR, Wilets I. Neonatal opiate abstinence syndrome in term and preterm infants. J Pediatr 1991; 118: 933-7
51. Finnegan LP, Kron R, Connaughthon JJ, et al. A scoring system for evaluation and treatment of the neonatal abstinence syndrome: a new clinical and research tool. In: Morselli P, Garattini S, Sereni F, editors. Basic and therapeutic aspects of perinatal pharmacology. New York: Raven Press, 1975: 139-52
52. Wilson G. Clinical studies of infants and children exposed prenatally to heroin. Ann NY Acad Sci 1989; 562: 183-94
53. Ostrea EM, Chavez CJ, Strauss ME. A study of factors that influence the severity of neonatal narcotic withdrawal. J Pediatr 1976 Apr; 88 (4 Pt 1): 642-5
54. Olson KR, McGuigan MA. Neonatal abstinence syndrome. In: Rudolph AM, Hoffman JIE, Rudolph CD, editors. Rudolph's pediatrics. 20th ed. Norwalk (CT): Appleton & Lange, 1996: 839-41
55. Ostrea FM, Lucena JL, Silvestre MA. The infant of the drug-dependent mother. In: Avery GB, Fletcher MA, MacDonald MG, editors. Neonatology: pathophysiology and management of the newborn. 4th ed. Philadelphia: JP Lippincott, 1994: 1300-33
56. Herzlinger RA, Kandall SR, Vaughan HG. Neonatal seizures associated with narcotic withdrawal. J Pediatr 1977 Oct; 91 (4): 638-41
57. Chasnoff IJ, Burns WJ. The Moro Reaction: a scoring system for neonatal narcotic withdrawal. Dev Med Child Neurol 1984; 26: 484-9
58. Green M, Suffet F. The neonatal narcotic withdrawal index: a device for the improvement of care in the abstinence syndrome. Am J Drug Alcohol Abuse 1981;8:203-13
59. Kandall S, Doberczak T, Mauer K, et al. Opiate vs CNS depressant therapy in neonatal drug abstinence syndrome. Am J Dis Child 1983; 137: 378-82
60. Koren G, Levy M. Pediatric uses of opioids. Pediatr Clin North Am 1989; 36: 1141-56
61. Levy M, Spino M. Neonatal withdrawal syndrome: associated drugs and pharmacologic management. Pharmacotherapy 1993; 13 (3): 202-11
62. Zelson C. Acute management of neonatal addiction. Addict Dis 1975; 2: 159-68
63. Kliegman R. Substance abuse and withdrawals. In: Nelson WE, Behrman RE, Kliegman RM, et al., editors. Nelson's text book of pediatrics. 15th ed. Philadelphia: Saunders, 1996: 508-10
64. Carin I, Glass L. Parekh A, et al. Neonatal methadone withdrawal: effect of two treatment regimens. Am J Dis Child 1983; 137: 1166-9
65. Nathenson G, Golden G, Litt I. Diazepam in the management of neonatal narcotic withdrawal syndrome. Pediatrics 1971; 48: 523-7
66. Kahn EJ, Neumann LL, Polk GA. The course of the heroin withdrawal syndrome in neonates treated with phenobarbital or chlorpromazine. J Pediatr 1969; 75: 495-502
67. Madden JD, Chappel JN, Zuspan F, et al. Observation and treatment of neonatal narcotic withdrawal. Am J Obstet Gynecol 1989; 127: 199-201
68. Neumann L, Cohen S. The neonatal narcotic withdrawal syndrome: a therapeutic challenge. Clin Perinatol 1975; 2: 99-109
69. Hoder E, Leckman J, Ehrenkranz R, et al. Clonidine in neonatal narcotic-abstinence syndrome [letter]. N Engl J Med 1981; 305: 1284
70. Washton A, Resnick R. Clonidine in opiate withdrawal: review and appraisal of clinical findings. Pharmacotherapy 1981; 1: 140-6