Pharmacokinetics and pharmacodynamics during treatment with the omeprazole 20 mg enteric-coated tablet and 20 mg capsule in asymptomatic duodenal ulcer patients

Canadian Journal of Gastroenterology

Volumn 11, Issue 8, 1997, Pages 657-660

  Thomson, A B R ^a   Kirdeikis, P ^b   Lastiwka, R ^b   Rohss K ^b   Sinclair, P ^b   Olofsson, B ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b NONE

Author keywords

Bioavailability; Intragastric pH profile; Omeprazole capsule; Omeprazole enteric coated tablet; Repeated dosing conditions

Indexed keywords

OMEPRAZOLE; PROTON PUMP INHIBITOR;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; DUODENUM ULCER; ENTERIC COATED TABLET; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PHARMACODYNAMICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REMISSION; STOMACH PH; TIME;

EID: 0031458698     PISSN: 08357900     EISSN: None     Source Type: Journal    
DOI: 10.1155/1997/910471     Document Type: Article

References (3)

1. Thomson ABR, Sinclair P, Matisko A, Rosen E, Andersson T, Olofsson B. Influence of food on the bioavailability of an enteric-coated tablet formulation of omeprazole 20 mg under repeated dose conditions. Can J Gastroenterol 1997;11:663-7.
2. Burger DW, Chriverton SG, Hunt RN. Is there an optional degree of acid suppression for healing of duodenal ulcers? Gastroenterology 1990;99:345-51.
3. Lagerström PO, Persson BA. Determination of omeprazole and metabolites in plasma and urine by liquid chromatography. J Chromatogr 1984;309:347-56.