-
1
-
-
0017309766
-
Structural patterns in globular proteins
-
Levitt, M. and Chothia, C. Structural patterns in globular proteins. Nature (London) 1976, 261, 552-558
-
(1976)
Nature (London)
, vol.261
, pp. 552-558
-
-
Levitt, M.1
Chothia, C.2
-
2
-
-
0029035985
-
Thrombopoietin: The primary regulator of platelet production
-
Kaushansky, K. Thrombopoietin: The primary regulator of platelet production. Blood 1995, 86, 419-431
-
(1995)
Blood
, vol.86
, pp. 419-431
-
-
Kaushansky, K.1
-
3
-
-
0028302409
-
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
-
de Sauvage, F.J., et al. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature (London) 1994, 369, 533-538
-
(1994)
Nature (London)
, vol.369
, pp. 533-538
-
-
De Sauvage, F.J.1
-
4
-
-
0030461838
-
Peptide, disulfide, and glycosyla-tion mapping of recombinant human thrombopoietin from Serl to Arg246
-
Huffman, R.C, et al. Peptide, disulfide, and glycosyla-tion mapping of recombinant human thrombopoietin from Serl to Arg246. Biochemistry 1996, 35, 14849-14861
-
(1996)
Biochemistry
, vol.35
, pp. 14849-14861
-
-
Huffman, R.C.1
-
5
-
-
0028199208
-
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
-
Lok, S. Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature (London) 1994, 369, 565-568
-
(1994)
Nature (London)
, vol.369
, pp. 565-568
-
-
Lok, S.1
-
6
-
-
2442771182
-
Essential structure for biological activity of thrombopoietin
-
Kato, T., et al. Essential structure for biological activity of thrombopoietin. Blood 1995, 86, 1448
-
(1995)
Blood
, vol.86
, pp. 1448
-
-
Kato, T.1
-
7
-
-
0029086661
-
Characterisation of the truncated thrombopoietin variants
-
Wada, T., et al. Characterisation of the truncated thrombopoietin variants. Biochem. Biophys. Res. Commun. 1995, 213, 1091-1098
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.213
, pp. 1091-1098
-
-
Wada, T.1
-
8
-
-
0023550727
-
Structural characterisation of natural human urinary and recombinant DNA derived erythropoietin
-
Recny, M.A., et al. Structural characterisation of natural human urinary and recombinant DNA derived erythropoietin. J. Biol. Chem. 1987, 262, 17156-17163
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 17156-17163
-
-
Recny, M.A.1
-
9
-
-
0345049872
-
Biological role of the C terminal region of human thrombopoietin
-
Muto, T., et al. Biological role of the C terminal region of human thrombopoietin. Protein Eng. 1996, 9, 20
-
(1996)
Protein Eng.
, vol.9
, pp. 20
-
-
Muto, T.1
-
10
-
-
0029020445
-
Thrombopoietin, the cMpl ligand is a major regulator of platelet production
-
Broudy, C.V. and Kaushansky, K. Thrombopoietin, the cMpl ligand is a major regulator of platelet production. J. Leuk. Biol. 1995, 57, 719-725
-
(1995)
J. Leuk. Biol.
, vol.57
, pp. 719-725
-
-
Broudy, C.V.1
Kaushansky, K.2
-
11
-
-
0025326350
-
A new cytokine receptor superfamily
-
Cosman, D., et al. A new cytokine receptor superfamily. Trends Biochem. Sci. 1990, 15, 265-270
-
(1990)
Trends Biochem. Sci.
, vol.15
, pp. 265-270
-
-
Cosman, D.1
-
12
-
-
13244295613
-
Hematopoietin sub-family classification based on size, gene organization and sequence homology
-
Boulay, J.L. and Paul, W.E. Hematopoietin sub-family classification based on size, gene organization and sequence homology. Curr. Biol. 1993, 3, 573-581
-
(1993)
Curr. Biol.
, vol.3
, pp. 573-581
-
-
Boulay, J.L.1
Paul, W.E.2
-
13
-
-
0027482752
-
Hematopoietic growth factors: Understanding functional diversity in structural terms
-
Kaushansky, K. and Karplus, P.A. Hematopoietic growth factors: Understanding functional diversity in structural terms. J. Am. Soc. Hematol. 1993, 82, 3229-3240
-
(1993)
J. Am. Soc. Hematol.
, vol.82
, pp. 3229-3240
-
-
Kaushansky, K.1
Karplus, P.A.2
-
14
-
-
0027145507
-
Cytokine structural taxonomy and mechanisms of receptor engagement
-
Sprang, S.R. and Bazan, J.F. Cytokine structural taxonomy and mechanisms of receptor engagement. Curr. Opin. Struct. Biol. 1993, 3, 815-827
-
(1993)
Curr. Opin. Struct. Biol.
, vol.3
, pp. 815-827
-
-
Sprang, S.R.1
Bazan, J.F.2
-
15
-
-
0028887623
-
Cytokines and their receptor complexes
-
Davies, R.D. and Wlodawer, A. Cytokines and their receptor complexes. FASEB J. 1995, 9, 50-56
-
(1995)
FASEB J.
, vol.9
, pp. 50-56
-
-
Davies, R.D.1
Wlodawer, A.2
-
16
-
-
0028899548
-
Genomic structure, chromosomal localization, and conserved alternative splice forms of thrombopoietin
-
Gurney, A.L., et al. Genomic structure, chromosomal localization, and conserved alternative splice forms of thrombopoietin. Blood 1995, 4, 981-988
-
(1995)
Blood
, vol.4
, pp. 981-988
-
-
Gurney, A.L.1
-
17
-
-
0029982521
-
Hematopoietic receptor complexes
-
Wells, J.A. and Vos, A.M. Hematopoietic receptor complexes. Annu. Rev. Biochem. 1996, 65, 609-634
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 609-634
-
-
Wells, J.A.1
Vos, A.M.2
-
18
-
-
0025162844
-
Structural design and molecular evolution of a cytokine receptor superfamily
-
Bazan, J.F. Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl. Acad. Sci. U.S.A. 1990, 87, 6934-6938
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 6934-6938
-
-
Bazan, J.F.1
-
19
-
-
0027943660
-
Comparison of the intermediate complexes of hGH bound to hGHR and prolactin receptors
-
Kossiakoff, A.A., et al. Comparison of the intermediate complexes of hGH bound to hGHR and prolactin receptors. Protein Sci. 1994, 3, 1697
-
(1994)
Protein Sci.
, vol.3
, pp. 1697
-
-
Kossiakoff, A.A.1
-
20
-
-
0028832719
-
Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity
-
Alexander, W.S., et al. Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity. EMBO J. 1995, 14, 5569-5578
-
(1995)
EMBO J.
, vol.14
, pp. 5569-5578
-
-
Alexander, W.S.1
-
21
-
-
0029049709
-
Distinct regions of c-Mpl cytoplasmic domain are coupled to the Jak-Stat signal transduction pathway and SCH phosphorylation
-
Gurney, A.L., et al. Distinct regions of c-Mpl cytoplasmic domain are coupled to the Jak-Stat signal transduction pathway and SCH phosphorylation. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 5292-5296
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 5292-5296
-
-
Gurney, A.L.1
-
22
-
-
0026684707
-
Molecular cloning and characterisation of Mpl, the human homolog of the v-Mpl oncogene: Identification of a member of the hematopoietic growth factor receptor superfamily
-
Vigon, I., et al. Molecular cloning and characterisation of Mpl, the human homolog of the v-Mpl oncogene: Identification of a member of the hematopoietic growth factor receptor superfamily, Proc. Natl. Acad. Sci. U.S.A. 1992, 89, 5640-5644
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 5640-5644
-
-
Vigon, I.1
-
23
-
-
0029960144
-
Thrombopoietin: Biological and preclinical properties
-
Kaushansky, K. Thrombopoietin: Biological and preclinical properties. Leukemia 1996, 10, S146-S148
-
(1996)
Leukemia
, vol.10
-
-
Kaushansky, K.1
-
24
-
-
0345049851
-
Thrombopoietin
-
Thompson, C. Thrombopoietin. Lancet 1994, 343, 1630
-
(1994)
Lancet
, vol.343
, pp. 1630
-
-
Thompson, C.1
-
25
-
-
0029798402
-
Mimicary of a protein hormone by a peptide agonist: The Epo receptor complex at 2.8Å
-
Livnah, O., et al. Mimicary of a protein hormone by a peptide agonist: The Epo receptor complex at 2.8Å. Science 1996, 273, 464-471
-
(1996)
Science
, vol.273
, pp. 464-471
-
-
Livnah, O.1
-
26
-
-
0344187651
-
Oxford Molecular
-
Oxford
-
Oxford Molecular. CAMELEON 3.13. Oxford Molecular, Oxford, 1995
-
(1995)
CAMELEON 3.13
-
-
-
27
-
-
0026598960
-
Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
-
Vos, A.M., et al. Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex. Science 1992, 255, 306-312
-
(1992)
Science
, vol.255
, pp. 306-312
-
-
Vos, A.M.1
-
28
-
-
0028916599
-
A hot spot of binding energy in a hormone-receptor interface
-
Clackson, T. and Wells, J.A. A hot spot of binding energy in a hormone-receptor interface;. Science 1995, 267, 383-386
-
(1995)
Science
, vol.267
, pp. 383-386
-
-
Clackson, T.1
Wells, J.A.2
-
29
-
-
0029975623
-
Identification of a critical binding determinant of the human erythropoietin receptor
-
Middleton, A.S., et al. Identification of a critical binding determinant of the human erythropoietin receptor. J. Biol. Chem. 1996, 271, 14045-14054
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14045-14054
-
-
Middleton, A.S.1
-
30
-
-
0004000664
-
-
Tripos Associates, St. Louis, Missouri
-
Tripos. Sybyl 6.1. Tripos Associates, St. Louis, Missouri, 1994
-
(1994)
Sybyl 6.1
-
-
-
31
-
-
0000179199
-
Composer
-
Sutcliffe, M.J., Haneef, I., Carney, D., and Blundell, T.L. Composer. Protein Eng. 1987, 1, 385-392
-
(1987)
Protein Eng.
, vol.1
, pp. 385-392
-
-
Sutcliffe, M.J.1
Haneef, I.2
Carney, D.3
Blundell, T.L.4
-
32
-
-
84988115618
-
Tripos force field
-
Clark, M., Cramer, R.D. III, and van Opdenbosh, N. Tripos force field. J. Comput. Chem. 1989, 10, 982-1012
-
(1989)
J. Comput. Chem.
, vol.10
, pp. 982-1012
-
-
Clark, M.1
Cramer R.D. III2
Van Opdenbosh, N.3
-
33
-
-
0004279414
-
-
University of California at San Francisco, San Francisco, California
-
Pearlman, D.A., et al. AMBER 4.1. University of California at San Francisco, San Francisco, California, 1994
-
(1994)
AMBER 4.1
-
-
Pearlman, D.A.1
-
34
-
-
0000884050
-
Unravelling the structure of IL-2 response
-
McKay, D.B. Unravelling the structure of IL-2 response. Science, 1992, 257, 412-413
-
(1992)
Science
, vol.257
, pp. 412-413
-
-
McKay, D.B.1
-
35
-
-
0026661731
-
Crystal structure of human recombinant interleukin-4 (IL-4) at 2.25Å resolution
-
Wlodawer, A., Pavslovsky, A., and Gutschina, A. Crystal structure of human recombinant interleukin-4 (IL-4) at 2.25Å resolution. FEBS Lett. 1992, 309, 59-64
-
(1992)
FEBS Lett.
, vol.309
, pp. 59-64
-
-
Wlodawer, A.1
Pavslovsky, A.2
Gutschina, A.3
-
36
-
-
0026320870
-
Novel fold and putative receptor-binding site of granulocyte macrophage colony stimulating factor
-
Diederichs, K., Boone, T., and Karplus, B.A. Novel fold and putative receptor-binding site of granulocyte macrophage colony stimulating factor. Science 1991, 254, 1779-1782
-
(1991)
Science
, vol.254
, pp. 1779-1782
-
-
Diederichs, K.1
Boone, T.2
Karplus, B.A.3
-
37
-
-
0029995377
-
A partial model of the erythropoietin receptor complex
-
Caravella, J.A., Lyne, P.D., and Richards, W.G. A partial model of the erythropoietin receptor complex. Proteins 1996, 24, 394-401
-
(1996)
Proteins
, vol.24
, pp. 394-401
-
-
Caravella, J.A.1
Lyne, P.D.2
Richards, W.G.3
-
38
-
-
0020699991
-
Structure and expression of a cloned cDNA for human interleukin-2
-
Tanguchi, T., et al. Structure and expression of a cloned cDNA for human interleukin-2. Nature (London), 1983, 302, 305-310
-
(1983)
Nature (London)
, vol.302
, pp. 305-310
-
-
Tanguchi, T.1
-
39
-
-
0042927891
-
Isolation and characterisation of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor-I, that expresses B-cell-stimulating and T-cell-stimulating activities
-
Yokota, T., et al. Isolation and characterisation of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor-I, that expresses B-cell-stimulating and T-cell-stimulating activities. Proc. Natl. Acad. Sci. U.S.A. 1986, 83, 5894-5898
-
(1986)
Proc. Natl. Acad. Sci. U.S.A.
, vol.83
, pp. 5894-5898
-
-
Yokota, T.1
-
40
-
-
0642284484
-
Isolation of cDNA for a human granulocyte macropage colony stimulating factor by functional expression in mammalian cells
-
Lee, F., et al. Isolation of cDNA for a human granulocyte macropage colony stimulating factor by functional expression in mammalian cells. Proc. Natl. Acad, Sci. U.S.A. 1985, 82, 4360-4364
-
(1985)
Proc. Natl. Acad, Sci. U.S.A.
, vol.82
, pp. 4360-4364
-
-
Lee, F.1
-
41
-
-
0344695781
-
Isolation and characterisation of genomic and cDNA clones of human erythropoietin
-
Jacobs, K., et al. Isolation and characterisation of genomic and cDNA clones of human erythropoietin. Nature (London) 1985, 313, 804-809
-
(1985)
Nature (London)
, vol.313
, pp. 804-809
-
-
Jacobs, K.1
-
42
-
-
0022380999
-
Characterisation of murine erythropoietin
-
Cutler, R.L., et al. Characterisation of murine erythropoietin. Exp. Hematol. 1985, 13, 899-905
-
(1985)
Exp. Hematol.
, vol.13
, pp. 899-905
-
-
Cutler, R.L.1
-
43
-
-
0023635603
-
Growth hormone receptor and serum binding protein purification, cloning and expression
-
Leung, D.W., et al. Growth hormone receptor and serum binding protein purification, cloning and expression. Nature (London) 1987, 330, 537-543
-
(1987)
Nature (London)
, vol.330
, pp. 537-543
-
-
Leung, D.W.1
-
44
-
-
0024403321
-
Interleukin-2 receptor beta chain gene generation of 3 receptor forms by cloned human alpha chain and beta chain cDNAs
-
Hatakeyama, M., et al. Interleukin-2 receptor beta chain gene generation of 3 receptor forms by cloned human alpha chain and beta chain cDNAs. Science 1989, 244, 551-556
-
(1989)
Science
, vol.244
, pp. 551-556
-
-
Hatakeyama, M.1
-
45
-
-
0025305497
-
Human interleukin-4 receptor confers biological responsiveness and defines a novel receptor superfamily
-
Idzerda, R.L., et al. Human interleukin-4 receptor confers biological responsiveness and defines a novel receptor superfamily. J. Exp. Med. 1990, 171, 861-873
-
(1990)
J. Exp. Med.
, vol.171
, pp. 861-873
-
-
Idzerda, R.L.1
-
46
-
-
0025738139
-
The erytropoietin receptor gene -cloning and identification of multiple transcripts in an erythroid cell line OCIM1
-
Ehrenman, K., et al. The erytropoietin receptor gene -cloning and identification of multiple transcripts in an erythroid cell line OCIM1. Exp. Hematol, 1991, 19, 973-977
-
(1991)
Exp. Hematol
, vol.19
, pp. 973-977
-
-
Ehrenman, K.1
-
47
-
-
0026244229
-
A program to produce both detailed and schematic plots of protein structures
-
Kraulis, P. A program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 1991, 24, 946-950
-
(1991)
J. Appl. Crystallogr.
, vol.24
, pp. 946-950
-
-
Kraulis, P.1
-
48
-
-
0027297047
-
Erythropoietin structure function relationships
-
Boissel, J.P., et al. Erythropoietin structure function relationships. J. Biol. Chem. 1993, 268, 15983-15993
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15983-15993
-
-
Boissel, J.P.1
-
49
-
-
0029930231
-
Fine structure epitope mapping of antierythropoietin monoclonal antibodies reveals a model of recombinant human erythropoietin structure
-
Elliot, S., et al. Fine structure epitope mapping of antierythropoietin monoclonal antibodies reveals a model of recombinant human erythropoietin structure. Blood 1996, 87, 2702-2713
-
(1996)
Blood
, vol.87
, pp. 2702-2713
-
-
Elliot, S.1
-
50
-
-
0000243829
-
PROCHECK
-
Laskowski, R.A., MacArthur, M.W., Moss, D.S., and Thornton, J.M. PROCHECK. J. Appl. Crystallogr. 1993, 26, 283-291
-
(1993)
J. Appl. Crystallogr.
, vol.26
, pp. 283-291
-
-
Laskowski, R.A.1
MacArthur, M.W.2
Moss, D.S.3
Thornton, J.M.4
-
51
-
-
0021107965
-
Solvent accessible surfaces of proteins and nucleic acids
-
Conolly, M.L. Solvent accessible surfaces of proteins and nucleic acids. Science 1983, 221, 709-713
-
(1983)
Science
, vol.221
, pp. 709-713
-
-
Conolly, M.L.1
-
52
-
-
0345049850
-
-
Molecular Simulations, Inc., Waltham, MA
-
QUANTA. Molecular Simulations, Inc., Waltham, MA, 1994
-
(1994)
QUANTA
-
-
-
53
-
-
0026727235
-
3-D structure of dimeric human recombinant macrophage colony stimulating factor
-
Pandit, J., Bohm, A., et al. 3-D structure of dimeric human recombinant macrophage colony stimulating factor. Science 1992, 258, 1358-1362
-
(1992)
Science
, vol.258
, pp. 1358-1362
-
-
Pandit, J.1
Bohm, A.2
-
54
-
-
0028363673
-
The crystal structure and biological function of leukemia inhibitory factor-implications for receptor binding
-
Robinson, R.C., et al. The crystal structure and biological function of leukemia inhibitory factor-implications for receptor binding. Cell 1994, 77, 1101-1116
-
(1994)
Cell
, vol.77
, pp. 1101-1116
-
-
Robinson, R.C.1
-
55
-
-
0030050701
-
Binding in the growth hormone receptor complex
-
Wells, J.A. Binding in the growth hormone receptor complex. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 1-6
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 1-6
-
-
Wells, J.A.1
-
56
-
-
0027451432
-
Two distinct functional sites of human interleukin-4 are identified by variants impaired in either receptor binding or receptor activation
-
Kruse, N., Sen, B.-J., Arnold, S., Tony, H.P., Muller, T., and Sebald, W. Two distinct functional sites of human interleukin-4 are identified by variants impaired in either receptor binding or receptor activation. EMBO J. 1993, 12, 5121-5129
-
(1993)
EMBO J.
, vol.12
, pp. 5121-5129
-
-
Kruse, N.1
Sen, B.-J.2
Arnold, S.3
Tony, H.P.4
Muller, T.5
Sebald, W.6
-
57
-
-
0027300652
-
Murine granulocyte macrophage colony stimulating factor using monoclonal antibodies to synthetic peptides
-
Greenfield, R.S., Braslawsky, G.R., Kadow, K.F., Spitalmy, G.L., Chace, D., Bull, C.O., and Bursucker, I. Murine granulocyte macrophage colony stimulating factor using monoclonal antibodies to synthetic peptides. J. Immunol. 1993, 150, 5241-5251
-
(1993)
J. Immunol.
, vol.150
, pp. 5241-5251
-
-
Greenfield, R.S.1
Braslawsky, G.R.2
Kadow, K.F.3
Spitalmy, G.L.4
Chace, D.5
Bull, C.O.6
Bursucker, I.7
-
58
-
-
0028064871
-
Erythropoietin structure function relationships: Identification of functionally important domains
-
Wen, D., Boissel, J.-P., Showers, M., Baird, C.R., and Bunn, H.F. Erythropoietin structure function relationships: Identification of functionally important domains. J. Biol. Chem. 1994, 269, 22839-22846
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 22839-22846
-
-
Wen, D.1
Boissel, J.-P.2
Showers, M.3
Baird, C.R.4
Bunn, H.F.5
-
59
-
-
0024596843
-
Hematopoietic activity of GM-CSF is dependent upon two distinct regions of the molecule: Functional analysis based upon the activities of interspecies hybrid growth factors
-
Kaushansky, K., Shoemaker, S.G., Alfaro, S., and Brown, C. Hematopoietic activity of GM-CSF is dependent upon two distinct regions of the molecule: Functional analysis based upon the activities of interspecies hybrid growth factors. Proc. Natl. Acad. Sci. U.S.A. 1989, 86, 1213-1221
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 1213-1221
-
-
Kaushansky, K.1
Shoemaker, S.G.2
Alfaro, S.3
Brown, C.4
-
60
-
-
0027373282
-
Definition and spatial location of mouse interleukin-2 residues that interact with its heterotrimeric receptor
-
Zurawski, S.M., Vega, F., Doyle, E.L., Huyghe, B., Flaherty, K., McKay, D.B., and Zurawski, G. Definition and spatial location of mouse interleukin-2 residues that interact with its heterotrimeric receptor. EMBO J. 1993, 12, 5113-5119
-
(1993)
EMBO J.
, vol.12
, pp. 5113-5119
-
-
Zurawski, S.M.1
Vega, F.2
Doyle, E.L.3
Huyghe, B.4
Flaherty, K.5
McKay, D.B.6
Zurawski, G.7
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