Synthesis and opiate activity of pseudo-tetrapeptides containing chiral piperazin-2-one and piperazine derivatives

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 12, 1997, Pages 1940-1944

  Yamashita, Tetsushi ^a   Tsuru, Eiji ^a   Banjyo, Eri ^a   Doe, Matsumi ^a   Shibata, Kozo ^a   Yasuda, Masahide ^b   Gemba, Munekazu ^b  

^a Osaka Prefecture University   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

N,N' ethylene bridged dipeptide; Opiate activity; Piperazine derivative; Pseudo tetrapeptide; Selective BH3 reduction; Structure activity relationship

Indexed keywords

OPIATE PEPTIDE; PIPERAZINE DERIVATIVE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOASSAY; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; ENANTIOMER; GUINEA PIG; MALE; MOUSE; NONHUMAN; PEPTIDE ANALYSIS; PEPTIDE SYNTHESIS; STRUCTURE ACTIVITY RELATION;

EID: 0031456798     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.1940     Document Type: Article

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