The role of smoothing techniques in the interpretation of results from genomic scans using sib-pair data

Genetic Epidemiology

Volumn 14, Issue 6, 1997, Pages 1047-1052

  Siegmund, K D ^a   Todorov, A A ^a   Rao, D C ^a   Borecki, I B ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Nonparametric linkage analysis; Quantitative trait loci

Indexed keywords

ALLELE; CONFERENCE PAPER; GENE; GENETIC LINKAGE; HUMAN; PEDIGREE; PHENOTYPE; QUANTITATIVE TRAIT; SIBLING; TECHNIQUE;

ALLELES; CHROMOSOMES, HUMAN, PAIR 8; DATA INTERPRETATION, STATISTICAL; GENETIC MARKERS; GENETIC SCREENING; GENOME, HUMAN; HUMANS; LINKAGE (GENETICS); MATCHED-PAIR ANALYSIS; NUCLEAR FAMILY; PREDICTIVE VALUE OF TESTS; QUANTITATIVE TRAIT, HERITABLE; REGRESSION ANALYSIS; STATISTICS, NONPARAMETRIC;

EID: 0031456695     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(1997)14:6<1047::AID-GEPI81>3.0.CO;2-H     Document Type: Conference Paper

References (5)

1. Cardon LR, Fulker DW (1994): The power of interval mapping of quantitative trait loci, using selected sib pairs. Am J Hum Genet 55:825-833.
2. CRI-MAP (1990): Documentation for CRJ-MAP, version 2.4, Department of Genetics, Washington University, St. Louis.
3. Goldgar DE (1990): Multipoint analysis of human quantitative genetic variation. Am J Hum Genet 47: 957-967.
4. Haseman JK, Elston RC (1972): The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 2:3-19.
5. Todorov AA (1992): Robust multipoint methods for linkage analysis. Unpublished Ph.D. dissertation, LSU Medical Center, New Orleans, LA.