Promotion of the formation of phenylalanine-thymine cross-linked products by free radicals formed during carbon tetrachloride activation with benzoyl peroxide in model systems. A mass spectrometric structural study

Research Communications in Molecular Pathology and Pharmacology

Volumn 98, Issue 1, 1997, Pages 85-90

  Castro, G D ^a   Castro, J A ^a  

^a Instituto de Investigaciones Cientificas y Tecnicas de Las Fuerzas Armadas   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOYL PEROXIDE; CARBON TETRACHLORIDE; FREE RADICAL; PHENYLALANINE; THYMINE;

ANALYTIC METHOD; ARTICLE; CHEMICAL REACTION; CROSS LINKING; GAS CHROMATOGRAPHY; ION CURRENT; MASS SPECTROMETRY; PRIORITY JOURNAL; REACTION ANALYSIS; TOXICOKINETICS;

BENZOYL PEROXIDE; CARBON TETRACHLORIDE; CROSS-LINKING REAGENTS; FREE RADICALS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; PHENYLALANINE; THYMINE;

EID: 0031456514     PISSN: 10780297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Castro G.D., Díaz Gomez M.I. and Castro J.A. (1991). Interaction ob trichloromethyl free radicals with phenylalanine. Arch. Toxicol., 65: 340-343.
2. Castro G.D. and Castro J.A. (1993). Cytosine attack by free radicals arising from bromotrichloromethane in the presence of benzoyl peroxide. Terat. Carcinog. Mutat., 13: 235-245.
3. Castro G.D., Simpson J.T. and Castro J.A. (1994a). Interaction of trichloromethyl free radicls with thymine in a model system. A mass spectrometric study. Chem. Biol. Interact., 90: 13-22.
4. Castro O.D., Stamato C.J. and Castro J.A. (1994b). Tyrosine attack by free radicals derived from catalytic decomposition of carbon tetrachloride. Free Rad. Biol. Med., 16: 693-701.
5. Castro G.D., Stamato C.J. and Castro J.A. (1994c). 5-methylcytosine attack by free radicals arising from bromotrichloromethane in a model system: Structure of reaction products formed. Free Rad. Biol, Med. 17: 419-428.
6. Castro G.D., Stamato C.J. and Castro J.A. (1994d), Proline interaction with trichloromethyl and trichloromethyl peroxyl free radicals in a model system. Studies about the nature of the reaction products formed. Drug Metab. Rev., 27: 257-275.
7. Castro G.D., Stamato C.J. and Castro J.A. (1995a). Reaction of bromotrichloromethane derived free radicals with uracil in a model system. Structures of products formed. Free Rad. Res., 23:431-442.
8. Castro G.D. and Castro J.A. (1995b). Tryptophan reaction with free radicals arisen from carbon tetrachloride in a model system. A mass spectrometric study. Redox Report, 2(1): 47-54.
9. Castro G.D, and Castro I.A. (1996). Hydroxyproline reaction with free radicals generated during benzoyl peroxide catalytic decompositon of carbon tetrachloride. Structure of reaction products formed. Amino Acids, 10: 283-294.
10. Castro G.D., Díaz Gomez M.I. and Castro J.A. (1997). DNA bases attack by reactive metabolites produced during carbon tetrachloride biotransformation and promotion of liver microsomal lipid peroxidation. Res. Commun. Mol. Pathol. Pharmacol., 95: 253-258.
11. Castro J.A. and Castro G.D. (1997). Chemically-induced free radical-mediated cell injury and toxicology. An. Soc. Cient. Arg., 227: 37-50.
12. Fanelli S.L., Castro G.D. and Castro J.A. (1995). Cholesterol interaction with free radicals produced from carbon tetrachloride or bromotrichloromethane by either catalytic decomposition or via liver microsomal activation. Chem, Biol. Interact., 98: 223-236.
13. Galelli M.E., Díaz Gómez M.I., Castro G.D. and Castro J.A. (1997). Carbon tetrachloride-induced free radical mediated protein oxidation in vitro and in vivo. Redox Report, 3: 23-29.