-
1
-
-
0020682197
-
Enzymatic toxicogenation of "activated" cyclophosphamide by 3′-5′exonucleases
-
Bielicki L, Voelcker G, Hohorst HJ (1983) Enzymatic toxicogenation of "activated" cyclophosphamide by 3′-5′exonucleases. J Cancer Res Clin Oncol 105:27-29
-
(1983)
J Cancer Res Clin Oncol
, vol.105
, pp. 27-29
-
-
Bielicki, L.1
Voelcker, G.2
Hohorst, H.J.3
-
2
-
-
0021165938
-
Activated cyclophosphamide: An enzyme-mechanism-based suicide inactivator of DNA polymerase/3′-5′ exonuclease
-
Bielicki L, Voelcker G, Hohorst HJ (1984) Activated cyclophosphamide: an enzyme-mechanism-based suicide inactivator of DNA polymerase/3′-5′ exonuclease. J Cancer Res Clin Oncol 107:195-198
-
(1984)
J Cancer Res Clin Oncol
, vol.107
, pp. 195-198
-
-
Bielicki, L.1
Voelcker, G.2
Hohorst, H.J.3
-
3
-
-
0017140119
-
Comparative pharmacologic study in vitro and in vivo with cyclophosphamide (NSC 26271), cyclophosphamide metabolites, and plain nitrogen mustard compounds
-
Brock N (1976) Comparative pharmacologic study in vitro and in vivo with cyclophosphamide (NSC 26271), cyclophosphamide metabolites, and plain nitrogen mustard compounds. Cancer Treat Rep 60:301-308
-
(1976)
Cancer Treat Rep
, vol.60
, pp. 301-308
-
-
Brock, N.1
-
4
-
-
84961018230
-
Über die Aktivierung von Cyclophosphamid in vivo und in vitro
-
Brock N, Hohorst HJ (1963) Über die Aktivierung von Cyclophosphamid in vivo und in vitro. Arzneimibtelforschung 13:1021-1031
-
(1963)
Arzneimibtelforschung
, vol.13
, pp. 1021-1031
-
-
Brock, N.1
Hohorst, H.J.2
-
5
-
-
0017346430
-
The problem of specificity and selectivity of alkylating cytostatics: Studies on N-2-chloroethylamido-oxazaphosphorines
-
Brock N, Hohorst HJ (1977) The problem of specificity and selectivity of alkylating cytostatics: studies on N-2-chloroethylamido-oxazaphosphorines. Z Krebsforsch Klin Onkol 88:185-215
-
(1977)
Z Krebsforsch Klin Onkol
, vol.88
, pp. 185-215
-
-
Brock, N.1
Hohorst, H.J.2
-
7
-
-
0015342392
-
Observations on the metabolism of cyclophosphamide
-
Connors TA, Foster AB, Gilsenan AM, Jarman M, Tisdale MJ (1972) Observations on the metabolism of cyclophosphamide. Biochem Pharmacol 21:1373-1376
-
(1972)
Biochem Pharmacol
, vol.21
, pp. 1373-1376
-
-
Connors, T.A.1
Foster, A.B.2
Gilsenan, A.M.3
Jarman, M.4
Tisdale, M.J.5
-
8
-
-
0015968586
-
Some studies of the active intermediate formed in the microsomal metabolism of cyclophosphamide and ifosphamide
-
Connors TA, Cox PJ, Farmer PB, Foster AB, Jarman M (1974) Some studies of the active intermediate formed in the microsomal metabolism of cyclophosphamide and ifosphamide. Biochem Pharmacol 23:115-129
-
(1974)
Biochem Pharmacol
, vol.23
, pp. 115-129
-
-
Connors, T.A.1
Cox, P.J.2
Farmer, P.B.3
Foster, A.B.4
Jarman, M.5
-
9
-
-
15144345677
-
-
Inaugural Dissertation zur Erlangung des Doktorgrades der Naturwissenschaften, Fachbereich Biochemie, Pharmazie und Lebensmittelchemie der Johann Wolfgang Goethe-Universität Frankfurt /M
-
Dausmann D (1988) Synthese von N,N-Bis-(2-chlorethyl-)-Phosphorsäureamid-Derivaten als Substrat für 3′-5′Exonukleasen und Untersuchungen zur Umsetzung von "aktiviertem cyclophosphamid" mit 1,2- und 1,3 Dinukleophilen. Inaugural Dissertation zur Erlangung des Doktorgrades der Naturwissenschaften, Fachbereich Biochemie, Pharmazie und Lebensmittelchemie der Johann Wolfgang Goethe-Universität Frankfurt /M
-
(1988)
Synthese von N,N-Bis-(2-chlorethyl-)-Phosphorsäureamid-Derivaten als Substrat für 3′-5′Exonukleasen und Untersuchungen zur Umsetzung von "Aktiviertem Cyclophosphamid" Mit 1,2- und 1,3 Dinukleophilen
-
-
Dausmann, D.1
-
10
-
-
0017195724
-
Deactivation of cyclophosphamide (NSC 26271) metabolites by sulfhydryl compounds
-
Draeger U, Peter G, Hohorst HJ (1976) Deactivation of cyclophosphamide (NSC 26271) metabolites by sulfhydryl compounds. Cancer Treat Rep 60:423-427
-
(1976)
Cancer Treat Rep
, vol.60
, pp. 423-427
-
-
Draeger, U.1
Peter, G.2
Hohorst, H.J.3
-
11
-
-
33947480040
-
Colorimetric estimation of nitrogen mustards in aqueous media
-
Friedman OM, Boger E (1961) Colorimetric estimation of nitrogen mustards in aqueous media. Anal Chem 33:906-910
-
(1961)
Anal Chem
, vol.33
, pp. 906-910
-
-
Friedman, O.M.1
Boger, E.2
-
12
-
-
0014060675
-
Determination of sulfhydryl groups with 2,2 and 4,4dithiodipyridine
-
Grasetti DR, Murray TF Jr (1967) Determination of sulfhydryl groups with 2,2 and 4,4dithiodipyridine. Arch Biochem Biophys 119:41-49
-
(1967)
Arch Biochem Biophys
, vol.119
, pp. 41-49
-
-
Grasetti, D.R.1
Murray Jr., T.F.2
-
14
-
-
0015105481
-
4-Ketocyclophosphamide a metabolite of cyclophosphamide. Formation, chemical and biological properties
-
Hohorst HJ, Ziemann A, Brock N (1971) 4-Ketocyclophosphamide a metabolite of cyclophosphamide. Formation, chemical and biological properties. Arzneimibtelforschung 21:1254-1257
-
(1971)
Arzneimibtelforschung
, vol.21
, pp. 1254-1257
-
-
Hohorst, H.J.1
Ziemann, A.2
Brock, N.3
-
15
-
-
0017182158
-
The problem of oncostatic specificity of cyclophosphamide (NSC-2627 1): Studies on reactions that control the alkylating and cytotoxic activity
-
Hohorst HJ, Draeger U, Peter G, Voelcker G (1976) The problem of oncostatic specificity of cyclophosphamide (NSC-2627 1): studies on reactions that control the alkylating and cytotoxic activity. Cancer Treat Rep 60:309-315
-
(1976)
Cancer Treat Rep
, vol.60
, pp. 309-315
-
-
Hohorst, H.J.1
Draeger, U.2
Peter, G.3
Voelcker, G.4
-
17
-
-
0023909774
-
Low toxicity cancer chemotherapy by suicide inactivation of DNA polymerase holoenzyme: First results with new thiazolidinyl- and perhydrothiazinyl-ethyl-N-mustard-phosphamide-esters
-
Hohorst HJ, Bielicki L, Müller K, Voelcker G (1988) Low toxicity cancer chemotherapy by suicide inactivation of DNA polymerase holoenzyme: first results with new thiazolidinyl- and perhydrothiazinyl-ethyl-N-mustard-phosphamide-esters, J Cancer Res Clin Oncol 114:309-311
-
(1988)
J Cancer Res Clin Oncol
, vol.114
, pp. 309-311
-
-
Hohorst, H.J.1
Bielicki, L.2
Müller, K.3
Voelcker, G.4
-
18
-
-
0026610907
-
DNA polymerase ε: In search of a function
-
Hübscher U, Thömmes P (1992) DNA polymerase ε: in search of a function. Trends Biochem Sci 17:55-58
-
(1992)
Trends Biochem Sci
, vol.17
, pp. 55-58
-
-
Hübscher, U.1
Thömmes, P.2
-
20
-
-
15444340478
-
Die Aufnahme von Taurin in Ehrlich Ascites Tumorzellen
-
Kromphardt H (1963) Die Aufnahme von Taurin in Ehrlich Ascites Tumorzellen. Biochem Z 339:233-254
-
(1963)
Biochem Z
, vol.339
, pp. 233-254
-
-
Kromphardt, H.1
-
21
-
-
0001063348
-
The deoxyribonuclease of Escherichia coli. IV. An exonuclease activity present in purified preparations of deoxyribonucleic acid polymerase
-
Lehman IR, Richardson CC (1964) The deoxyribonuclease of Escherichia coli. IV. An exonuclease activity present in purified preparations of deoxyribonucleic acid polymerase. J Biol Chem 239:233-241
-
(1964)
J Biol Chem
, vol.239
, pp. 233-241
-
-
Lehman, I.R.1
Richardson, C.C.2
-
22
-
-
0018602558
-
Synthesis and preliminary anti-tumor evaluation of 4(SR)-sulfido-cyclophosphamide
-
Peter G, Hohorst HJ (1979) Synthesis and preliminary anti-tumor evaluation of 4(SR)-sulfido-cyclophosphamide. Cancer Chemother Pharmacol 3:181-188
-
(1979)
Cancer Chemother Pharmacol
, vol.3
, pp. 181-188
-
-
Peter, G.1
Hohorst, H.J.2
-
23
-
-
0017152973
-
Studies on 4-hydroperoxy-cyclophosphamide (NSC 181815): A simple preparation method and its application for the synthesis of a new class of "activated" sulfur-containing cyclophosphamide (NSC 26271) derivatives
-
Peter G, Wagner T, Hohorst HJ (1976) Studies on 4-hydroperoxy-cyclophosphamide (NSC 181815): a simple preparation method and its application for the synthesis of a new class of "activated" sulfur-containing cyclophosphamide (NSC 26271) derivatives. Cancer Treat Rep 60:429-435
-
(1976)
Cancer Treat Rep
, vol.60
, pp. 429-435
-
-
Peter, G.1
Wagner, T.2
Hohorst, H.J.3
-
24
-
-
0015308178
-
Therapeutic efficacy of cyclophosphamide as a function of its metabolism
-
Sladek NE (1972) Therapeutic efficacy of cyclophosphamide as a function of its metabolism. Cancer Res 32:535-542
-
(1972)
Cancer Res
, vol.32
, pp. 535-542
-
-
Sladek, N.E.1
-
25
-
-
0015607955
-
Evidence for an aldehyde possessing alkylating activity as the primary metabolite of cyclophosphamide
-
Sladek NE (1973a) Evidence for an aldehyde possessing alkylating activity as the primary metabolite of cyclophosphamide. Cancer Res 33:651-658
-
(1973)
Cancer Res
, vol.33
, pp. 651-658
-
-
Sladek, N.E.1
-
26
-
-
0015786178
-
Bioassay and relative cytotoxic potency of cyclophosphamide metabolites generated in vitro and in vivo
-
Sladek NE (1973b) Bioassay and relative cytotoxic potency of cyclophosphamide metabolites generated in vitro and in vivo. Cancer Res 33:1150-1159
-
(1973)
Cancer Res
, vol.33
, pp. 1150-1159
-
-
Sladek, N.E.1
-
27
-
-
0017115562
-
Identification and pharmacokinetics of cyclophosphamide (NSC 26271) metabolites in vivo
-
Voelcker G, Wagner T, Hohorst HJ (1976) Identification and pharmacokinetics of cyclophosphamide (NSC 26271) metabolites in vivo. Cancer Treat Reps, 60:415-422
-
(1976)
Cancer Treat Reps
, vol.60
, pp. 415-422
-
-
Voelcker, G.1
Wagner, T.2
Hohorst, H.J.3
-
29
-
-
0018339832
-
Die intravenöse Injektion über den retrobulbären Plexus bei der Maus
-
Voelcker G, Fortmeyer HP (1979) Die intravenöse Injektion über den retrobulbären Plexus bei der Maus. Z Versuchtierkd 21:177-181
-
(1979)
Z Versuchtierkd
, vol.21
, pp. 177-181
-
-
Voelcker, G.1
Fortmeyer, H.P.2
-
30
-
-
0018788608
-
Fluorometrische Bestimmung von "aktiviertem" Cyclophosphamid und Ifosfamid im Blut
-
Voelcker G, Haeglsperger R, Hohorst HJ (1979) Fluorometrische Bestimmung von "aktiviertem" Cyclophosphamid und Ifosfamid im Blut. J Cancer Res Clin Oncol 93:233-240
-
(1979)
J Cancer Res Clin Oncol
, vol.93
, pp. 233-240
-
-
Voelcker, G.1
Haeglsperger, R.2
Hohorst, H.J.3
-
31
-
-
0019423750
-
Evidence for enzymatic toxification of "activated" cyclophosphamide (4-hydroxycyclophosphamide)
-
Voelcker G, Bielicki L, Hohorst HJ (1981) Evidence for enzymatic toxification of "activated" cyclophosphamide (4-hydroxycyclophosphamide) J Cancer Res Clin Oncol 99A:58-59
-
(1981)
J Cancer Res Clin Oncol
, vol.99 A
, pp. 58-59
-
-
Voelcker, G.1
Bielicki, L.2
Hohorst, H.J.3
-
33
-
-
0018923129
-
Butspiegel und Urin-Ausscheidung von aktiviertem Cyclophosphamid und seinen Deaktivierungsprodukten beim Menschen
-
Wagner T, Heydrich D, Voelcker G, Hohorst HJ (1980) Butspiegel und Urin-Ausscheidung von aktiviertem Cyclophosphamid und seinen Deaktivierungsprodukten beim Menschen. J Cancer Res Clin Oncol 96:79-92
-
(1980)
J Cancer Res Clin Oncol
, vol.96
, pp. 79-92
-
-
Wagner, T.1
Heydrich, D.2
Voelcker, G.3
Hohorst, H.J.4
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