In vitro and in vivo effects of β-carotene on rat epidermal lipoxygenases

International Journal for Vitamin and Nutrition Research

Volumn 67, Issue 6, 1997, Pages 407-414

  Lomnitski, Liat ^a   Grossman, Shlomo ^a   Bergman, Margalit ^a   Sofer, Yossi ^a   Sklan, David ^b  

^a BAR ILAN UNIVERSITY   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

carotene; Lipoxygenase; Oxidation; Rat; Skin; Ultraviolet

Indexed keywords

ARACHIDONIC ACID; BETA CAROTENE; CATALASE; LINOLEIC ACID; LIPOXYGENASE; LIPOXYGENASE INHIBITOR; MALONALDEHYDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL; ARTICLE; BINDING COMPETITION; DRUG EFFECT; ENZYMOLOGY; EPIDERMIS; FEMALE; LIPID PEROXIDATION; METABOLISM; RAT; ULTRAVIOLET RADIATION;

ANIMALS; ARACHIDONIC ACID; BETA CAROTENE; BINDING, COMPETITIVE; CATALASE; EPIDERMIS; FEMALE; LINOLEIC ACID; LIPID PEROXIDATION; LIPOXYGENASE; LIPOXYGENASE INHIBITORS; MALONDIALDEHYDE; RATS; THIOBARBITURIC ACID REACTIVE SUBSTANCES; ULTRAVIOLET RAYS;

EID: 0031456122     PISSN: 03009831     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Gardner, H.W. (1991) Recent investigations into the lipoxygenase pathway in plants. Biochim. Biophys. Acta 1084, 221-239.
2. Nikolaev, V., Reddanna, P., Whelan, J., Hildenbrandt, G. and Reddy, C.C. (1990) Stereochemical nature of the products of linoleic acid oxidation catalyzed by lipoxygenases from potato and soybean. Biochem. Biophys. Res. Commun. 170, 491-496.
3. Yamamoto, S. (1992) Mammalian lipoxygenases: molecular structure and functions. Biochim. Biophys. Acta 1128, 117-131.
4. Holtzman, M.J., Pentland, A., Baenziger, N.L. and Hansbrough, J.R. (1989) Heterogeneity of cellular expression of arachidonate 15-lipoxygenase: implications for biological activity. Biochim. Biophy. Acta, 1003, 204-208.
5. Ziboh, V.A. (1996) Arachidonic acid metabolism in the skin. In: Arachidonic Acid Metabolism and Tumor Promotion (Fischer, S.M. and Slaga, T.J., eds.) pp. 6-20, Martinus Nijhoff, Boston.
6. Ruzicka, T. and Printz, M.P. (1984) Arachidonic acid metabolism in skin: A review. Rev. Physiol. Biochem. Pharmacol. 100, 121-159.
7. Chan, C.C., Duhamel, L. and Ford-Hutchinson, A.W. (1985) Leukotriene B4 and 12-hydroxyeicosatetraenoic acid stimulate epidermal proliferation in vivo in the guinea pig. J. Invest. Dermatol. 85, 333-334.
8. Ruzicka, T. (1986) Lipoxygenase activity in cutaneous inflammation. In: New Trends in Allergy, II (Ring, J. and Burg, G., eds.) pp. 90-94, Germany.
9. Gschwendt, M., Furstenberger, G., Kittstein, W., Besemfelder, E., Hull, W.E., Hagerdorn, H., Opferkuch, H.J. and Marks, F. (1986) Generation of the arachidonic acid metabolite 8-HETE, by extracts of mouse skin treated with phorbol ester in vivo; identification by H-n.m.r. and GC-MS spectroscopy. Carcinogenesis 7, 449-455.
10. Furstenberger, G., Hagerdorn, H., Jacobi, T., Besemfelder, E., Stephan, M., Lehmann, W. and Marks, F. (1991) Characterization of an 8-lipoxygenase activity induced by the phorbol ester tumor promotor 12-0-tetradecanoyl phorbol-13-acetate in mouse skin in vivo. J. Biol. Chem. 266, 15738-15745.
11. Lomnitski, L., Sklan, D. and Grossman, S. (1995) Lipoxygenase activity in rat dermis and epidermis: partial purification and characterization. Biochim. Biophys. Acta 1255, 351-359.
12. Chang, J., Skowronek, M.D., Cherney, M.L. and Lewis, A.J. (1984) Differential effects of putative lipoxygenase inhibitors on arachidonic acid metabolism in cell-free and intact cell preparations. Inflammation 8, 143-155.
13. Lazer, E.S., Wong, H., Wegner, C.D., Graham, A.G. and Farina, P.R. (1990) Effect of structure on potency and selectivity in 2,6-disubstituted 4-(2-Arylethenyl) phenol lipoxygenase inhibitors. J. Med. Chem. 33, 1892-1898.
14. Burton, G.W. (1989) Antioxidant action of carotenoids. J. Nutr. 119, 109-111.
15. Rousseau, E.J., Davison, A.J. and Dunn, B. (1992) Protection by β-carotene and related compounds against oxygen-mediated cytotoxicity and genotoxicity: implications for carcinogenesis and anticarcinogenesis. Free Radical Biol. Med. 13, 407-433.
16. Burton, G.W. and Ingold, K.U. (1984) β-Carotene: An unusual type of lipid antioxidant. Science 224, 569-573.
17. Kennedy, T.A. and Liebler, D.C. (1992) Peroxyl radical scavenging by β-carotene in lipid bilayers. J. Biol. Chem. 267, 4658-4663.
18. Lomnitski, L., Bar-Natan, R., Sklan, D. and Grossman, S. (1993) The interaction between β-carotene and lipoxygenase in plant and animal systems. Biochim. Biophys. Acta 1167, 331-338.
19. Halevy, O. and Sklan, D. (1987) Inhibition of arachidonic acid oxidation by β-carotene, retinol and α-tocopherol. Biochim. Biophys. Acta 918, 304-307.
20. Nugteren, D.H., Christ-Hazelholf, E., Van der Beek, A. and Houtsmaller, U.M.T. (1985) Metabolism of linoleic acid and other essential fatty acids in the epidermis of the rat. Biochim. Biophys. Acta 834, 429-436.
21. Ruzicka, T., Vitto, A. and Printz, M.P. (1983) Epidermal arachidonate lipoxygenase. Biochim. Biophys. Acta 751, 369-374.
22. Grossman, S., (Shahin) Schon, I., Sofer, Y., Magid, N. and Bartoov, B. (1986) Arachidonic acid metabolizing enzymes in the ram reproductive system. In: Advances in Prostaglandin Thromboxane and Leukotriene Research (Zor, V. et al, eds.) pp. 241-252, Raven Press, New York.
23. Ben-Aziz, A., Grossman, S., Ascareli, I. and Budowski, P. (1970) Linoleate oxidation induced by lipoxygenase and heme proteins - A direct spectrophotometric assay. Anal. Biochem. 34, 88-100.
24. Grossman, S., Shahin, I. and Sredni, B. (1979) Characterization of products from linoleic acid. Biochim. Biophys. Acta 572, 293-297.
25. Lomnitski, L., Bergman, M., Schon, I. and Grossman, S. (1991) The effect of dietary vitamin E and β-carotene on oxidation processes in the rat testis. Biochim. Biophys. Acta 1082, 101-107.
26. Funk, M.O., Isaac, R. and Porter, N.A. (1976) Preparation and purification of lipid hydroperoxides from arachidonic acid and γ-linolenic acid. Lipids 11, 113-117.
27. Beers, R.F. and Sizer, I.W. (1952) A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J. Biol. Chem. 195, 133-140.
28. Morliere, P., Moysan, A., Santus, R., Huppe, G., Maziere, J.C. and Dubertret, L. (1991) UVA induced lipid peroxidation in cultured human fibroblasts. Biochim. Biophys. Acta 1084, 261-268.
29. Terao, J. (1989) Antioxidant activity of β-carotene-related carotenoids in solution. Lipids 24, 659-661.
30. Lim, B.P., Nagao, A., Terao, J., Tanaka, K., Suzuki, T. and Takama, K. (1992) Antioxidant activity of xanthophylls on peroxyl radical-mediated phospholipid peroxidation. Biochim. Biophys. Acta 1126, 178-184.
31. Palozza, P., Moualla, S. and Krinsky, N.I. (1992) Effect of β-carotene and α-tocopherol on radical initiated peroxidation of microsomes. Free Radical Biol. Med. 13, 127-136.
32. Klein, B.P., King, D. and Grossman, S. (1985) Cooxidation reactions of lipoxygenase in plant systems. Free Radical Biol. Med. 1, 309-343.
33. Parrish, J.A., Anderson, R.R., Urbach, F. and Pitts, D. (1978) Immediate and short term biological effects of ultraviolet radiation on normal skin. In: The Biological Effects of Ultraviolet Radiation on Normal Skin (Urbach, F. and Gange, R. W., eds.) pp. 107-139, Plenum Press, New York.
34. Gange, R.W. and Rosen, C.F. (1986) UVA effects on mammalian skin and cells. Photochem. Photobiol. 43, 701-705.
35. Kligman, L.H. and Kligman. A.M. (1989) The nature of photoaging: its prevention and repair. Photodermatol. 3, 215-217.
36. Peak, M.J., Peak, J.G. and Jones, C.A. (1985) Different direct and indirect mechanisms of the induction of DNA-protein crosslinks in human cells by far and near ultraviolet radiation: 290 and 405 nm. Photochem. Photobiol. 42, 141-146.
37. Punnonen, K., Jansen, C.T., Puntala, A. and Ahotupa, M. (1991) Effects of in vitro UVA irradiation and PUVA treatment on membrane fatty acids and activities of antioxidant enzymes in human keratinocytes. J. Invest. Dermatol. 96, 255-259.
38. Sondergaard, J. and Greaves, M.W. (1970) Pharmacological studies in inflammation due to exposure to ultraviolet radiation. J. Pathol. 101, 93-97.
39. Black, H.S. (1987) Potential involvement of free radical reactions in ultraviolet light-mediated cutaneous damage. Photochem. Photobiol. 46, 213-221.
40. Burrall, B. and Ziboh, V.A. (1986) Increased biosynthesis of lipoxygenase products by UVB-irradiated guinea-pig epidermis: evidence of a cyclooxygenase inhibitor. J. Invest. Dermatol. 86, 643-648.
41. Frederick, J.E., Snell, H.E. and Haywood, E.K. (1989) Solar ultraviolet at the earth's surface. Photochem. Photobiol. 50, 443-450.
42. 2α in human skin following ultraviolet B irradiation. Br. J. Clin. Pharmacol. 10, 453-457.
43. Barr, R.M., Brain, S.D., Black, A.K., Camp, R.D., Greaves, M.W., Mallet, A.I. and Wong, E. (1983) Lipoxygenase products of arachidonic acid in inflamed skin. J. Invest. Dermatol. 80, 345 (abstract).
44. DeLeo, V.A., Hanson, D., Weinstein, I.B. and Harber, L.C. (1985) Ultraviolet radiation stimulates the release of arachidonic acid from mammalian cells in culture. Photochem. Photobiol. 41, 51-56.
45. 2 and increased release of prostaglandin precursor from skin by ultraviolet irradiation. J. Invest. Dermatol. 70, 211 (abstract).
46. 14C-arachidonic acid in human keratinocytes in culture. Arch. Dermatol. Res. 278, 441-444.
47. Hanson. D. and DeLeo, V.A. (1989) Long wave ultraviolet irradiation stimulates arachidonic acid release and cyclo-oxygenase activity in mammalian cells in culture. Photochem. Photobiol. 49, 423-430.
48. Norkus, E.P., Bryce, G.F. and Bhagavan, H.N. (1993) Uptake and bioconversion of α-tocopheryl acetate to α-tocopherol in skin of hairless mice. Photochem. Photobiol. 57, 613-615.
49. Moysan, A., Marquis, I., Gaboriau, F., Santus, R., Dubertret, L. and Morliere, P. (1993) Ultraviolet A-induced lipid peroxidation and antioxidant defense systems in cultured human skin fibroblasts. J. Invest. Dermatol. 100, 692-698.
50. Fuchs, J., Huflejt, M.E., Rothfuss, L.M., Wilson, D.S., Carcamo, G. and Packer, L. (1989) Acute effects of near ultraviolet and visible light on the cutaneous antioxidant defense system, Photochem. Photobiol. 50, 739-744.
51. Aronoff, S. (1965) Catalase: Kinetics of photooxidation. Science 150, 72-73.
52. Kono, Y. and Fridovich, I. (1982) Superoxide radical inhibits catalase. J. Biol. Chem. 257, 5751-5754.