Merozoite surface protein-1 epitopes recognized by antibodies that inhibit Plasmodium falciparum merozoite dispersal

Molecular and Biochemical Parasitology

Volumn 90, Issue 1, 1997, Pages 223-234

  Lyon, Jeffrey A ^a   Carter, J Mark ^a   Thomas, Alan W ^a   Chulay, Jeffrey D ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

Antibody; Antigen; Epitope mapping; Immune complexes; Malaria; MSP I; Plasmodium falciparum

Indexed keywords

MEMBRANE PROTEIN;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; IMMUNOBLOTTING; MEROZOITE; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN DETERMINATION;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; CLONING, MOLECULAR; EPITOPE MAPPING; EPITOPES; ESCHERICHIA COLI; IMMUNE SERA; IMMUNOBLOTTING; MEROZOITE SURFACE PROTEIN 1; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PLASMODIUM FALCIPARUM; PROTEIN PRECURSORS; PROTOZOAN PROTEINS; RECOMBINANT FUSION PROTEINS;

PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0031455199     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(97)00155-2     Document Type: Article

References (32)

1. Amador R, Anderson RM, Aponte JJ, et al. In: Hoffman SL, editor. Malaria Vaccine Development: A Multi-immune Response Approach. Washington, DC: American Society of Microbiology Press, 1996.
2. Holder AA. Preventing merozoite invasion of erythrocytes. In: Hoffman SL, editor. Malaria Vaccine Development: A Multi-immune Response Approach. Washington, DC: American Society for Microboiology Press, 1996:77-104.
3. Laver W.G., Air G.M., Webster R.G., Smith-Gill S.J. Epitopes on protein antigens: Misconceptions and realities. Cell. 61:1990;553-556.
4. Pellequer J.L., Westhof E., Van Regenmortel M.H. Predicting location of continuous epitopes in proteins from their primary structures. Methods Enzymol. 203:1991;176-201.
5. Lew A.M., Langford C.J., Anders R.F.et al. A protective monoclonal antibody recognizes a linear epitope in the precursor to the major merozoite antigens of Plasmodium chabaudi adami. Proc Natl Acad Sci USA. 86:1989;3768-3772.
6. Dieckmann-Schuppert A., Bender S., Odenthal-Schnittler M., Bause E., Schwarz R.T. Apparent lack of N-glycosylation in the asexual intraerythrocytic stage of Plasmodium falciparum. Eur J Biochem. 205:1992;815-825.
7. Kimura E.A., Couto A.S., Peres V.J., Casal O.L., Katzin A.M. N-linked glycoproteins are related to schizogony of the intraerythrocytic stage in Plasmodium falciparum. J Biol Chem. 271:1996;14452-14461.
8. Lyon J.A., Haynes J.D., Diggs C.L., Chulay J.D., Pratt-Rossiter J.M. Plasmodium falciparum antigens synthesized by schizonts and stabilized at the merozoite surface by antibodies when schizonts mature in the presence of growth inhibitory immune serum. J Immunol. 136:1986;2252-2258.
9. Lyon J.A., Thomas A.W., Hall T., Chulay J.D. Specificities of antibodies that inhibit merozoite dispersal from malaria-infected erythrocytes. Mol Biochem Parasitol. 36:1989;77-85.
10. Thomas A.W., Carr D.A., Carter J.M., Lyon J.A. Sequence comparison of allelic forms of the Plasmodium falciparum merozoite surface antigen MSA2. Mol Biochem Parasitol. 43:1990;211-220.
11. Chulay J.D., Haynes J.D., Diggs C.L. Inhibition of in vitro growth of Plasmodium falciparum by immune serum from monkeys. J Infect Dis. 144:1981;270-278.
12. Weber J.L., Leininger W.M., Lyon J.A. Variation in the gene encoding a major merozoite surface antigen of the human malaria parasite Plasmodium falciparum. Nucleic Acids Res. 14:1986;3311-3323.
13. Weber J.L., Sim B.K., Lyon J.A., Wolff R. Merozoite surface protein sequence from the CAMP strain of the human malaria parasite Plasmodium falciparum. Nucleic Acids Res. 16:1988;1206-1207.
14. Sanger F., Nicklen S., Coulson A.R. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA. 74:1977;5463-5467.
15. Gross M., Sweet R.W., Sathe G.et al. Purlfication and characterization of human H-Ras proteins expressed in Escherichia coli. Mol Cell Biol. 5:1985;1015-1024.
16. Lyon J.A., Haynes J.D., Diggs C.L., Chulay J.D., Haidaris C.G., Pratt-Rossiter J. Monoclonal antibody characterization of the 195-kDa major surface glycoprotein of Plasmodium falciparum malaria schizonts and merozoites: Identification of additional processed products and a serotype-restricted repetitive epitope. J Immunol. 138:1987;895-901.
17. Geysen H.M., Rodda S.J., Mason T.J., Tribbick G., Schoofs P.G. Strategies for epitope analysis using peptide synthesis. J Immunol Methods. 102:1987;259-274.
18. Carter J.M. Epitope mapping of a protein using the Geysen (PEPSCAN) procedure. Methods Mol Biol. 36:1994;207-223.
19. Megret F., Hugnot J.P., Falconar A.et al. Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein. Virology. 187:1992;480-491.
20. Van Regenmortel M.H. Protein antigenicity. Mol Biol Rep. 16:1992;133-138.
21. Patarroyo M.E., Romero P., Torres M.L.et al. Induction of protective immunity against experimental infection with malaria using synthetic peptides. Nature. 328:1987;629-632.
22. Holder A.A., Freeman R.R., Nicholls S.C. Immunization against Plasmodium falciparum with recombinant polypeptides produced in Escherichia coli. Parasite Immunol. 10:1988;607-617.
23. Chang S.P., Case S.E., Gosnell W.L.et al. A recombinant baculovirus 42-kDa C-terminal fragment of Plasmodium falciparum merozoite surface protein-1 protects Aotus monkeys against malaria. Infect Immun. 64:1996;253-261.
24. Saul A., Lord R., Jones G., Geysen H.M., Gale J., Mollard R. Cross-reactivity of antibody against an epitope of the Plasmodium falciparum second merozoite surface antigen. Parasite Immunol. 11:1989;593-601.
25. Saul AM, Geysen M, Lord R. Delineation of epitopes on a Plasmodium falciparum merozoite surface antigen using monoclonal antibodies. In: Laskey R, editor. Technological Advances in Vaccine Development. New York: Alan R. Liss, 1988:547-551.
26. Tanabe K., Mackay M., Goman M., Scaife J.G. Allelic dimorphism in a surface antigen gene of the malaria parasite Plasmodium falciparum. J Mol Biol. 195:1987;273-287.
27. Trifilieff E., Dubs M.C., Van Regenmortel M.H. Antigenic cross-reactivity potential of synthetic peptides immobilized on polyethylene rods. Mol Immunol. 28:1991;889-896.
28. Blackman M.J., Ling I.T., Nicholls S.C., Holder A.A. Proteolytic processing of the Plasmodium falciparum merozoite surface protein-1 produces a membrane-bound fragment containing two epidermal growth factor-like domains. Mol Biochem Parasitol. 49:1991;29-33.
29. Burghaus P.A., Holder A.A. Expression of the 19-kDa carboxy-terminal fragment of the Plasmodium falciparum merozoite surface protein-1 in Escherichia coli as a correctly folded protein. Mol Biochem Parasitol. 64:1994;165-169.
30. Cheung A., Leban J., Shaw A.R.et al. Immunization with synthetic peptides of a Plasmodium falciparum surface antigen induces antimerozoite antibodies. Proc Natl Acad Sci USA. 83:1986;8328-8332.
31. Locher C.P., Tam L.Q., Chang S.P., McBride J.S., Siddiqui W.A. Plasmodium falciparum - gpl95 tripeptide repeat-specific monoclonal antibody inhibits parasite growth in vitro. Exp Parasitol. 84:1996;74-83.
32. Chang S.P., Kramer K.J., Yamaga K.M., Kato A., Case S.E., Siddiqui W.A. Plasmodium falciparum: Gene structure and hydropathy profile of the major merozoite surface antigen (gp195) of the Uganda-Palo Alto isolate. Exp Parasitol. 67:1988;1-11.