Transplantation of filgrastim-mobilized peripheral blood stem cells from HLA-identical sibling or alternative family donors in patients with hematologic malignancies: A prospective comparison on clinical outcome, immune reconstitution, and hematopoietic chimerism

Blood

Volumn 90, Issue 12, 1997, Pages 4725-4735

  Beelen, Dietrich W ^a   Ottinger, Helmut D ^a   Elmaagacli, Ahmet ^a   Scheulen, Birgit ^a   Basu, Oliver ^a   Kremens, Bernhard ^a   Havers, Werner ^a   Grosse Wilde, Hans ^a   Schaefer, Ulrich W ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADOLESCENT; ADULT; AGED; ALLOTRANSPLANTATION; ARTICLE; BLOOD DONOR; CHILD; CHIMERA; CLINICAL PROTOCOL; ERYTHROCYTE TRANSFUSION; FAMILY; FEMALE; GRAFT VERSUS HOST REACTION; HEMATOLOGIC DISEASE; HLA MATCHING; HUMAN; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; SIBLING; STATISTICAL ANALYSIS; STEM CELL TRANSPLANTATION; SURVIVAL; THROMBOCYTE TRANSFUSION; TREATMENT OUTCOME;

EID: 0031454791     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.12.4725     Document Type: Article

References (33)

1. Chao NJ, Schriber JR, Grimes K, Long GD, Negrin RS, Raimondi CM, Horning SJ, Brown SL, Miller L, Blume KG: Granulocyte colony-stimulating factor "mobilized" peripheral blood progenitor cells accelerate granulocyte and platelet recovery after high dose chemotherapy. Blood 81:2031, 1993
2. Sheridan WP, Begley CG, Juttner CA, Szer J, To LB, Maher D, McGrath KM, Morstyn G, Fox RM: Effect of peripheral-blood progenitor cells mobilized by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Lancet 339:640, 1992
3. Roberts MM, To LB, Gillis D, Mundy J, Rawling C, Ng K, Juttner CA: Immune reconstitution following peripheral blood stem cell transplantation, autologous bone marrow transplantation and allogeneic bone marrow transplantation. Bone Marrrow Transplant 12:469, 1993
4. Henon PR, Liang H, Beck-Wirth G, Eisenmann JC, Lepers M, Wunder E, Kandel G: Comparison of hematopoetic and immune recovery after autologous bone marrow or peripheral stem cell transplants. Bone Marrow Transplant 9:285, 1992
5. Bensinger WI, Price TH, Cale DC, Appelbaum FR, Clift R, Lilleby K, Williams B, Storb R, Thomas ED, Buckner CD: The effects of daily recombinant granulocyte colony-stimulating factor administration on normal granulocyte donors undergoing leukapheresis. Blood 81:1883, 1993
6. Tjonnfjord GE, Steen R, Evensen SA, Thorsby E, Egeland T: Characterisation of CD34+ peripheral blood cells from healthy adults mobilized by recombinant human granulocyte colony-stimulating factor. Blood 84:2795, 1994
7. Matsunaga T, Sakamaki, S, Kohgo Y, Ohi S, Hirayama Y, Niitsu Y: Recombinant human granulocyte colony-stimulating factor can mobilize sufficient amounts of peripheral blood stem cells in healthy volunteers for allogeneic transplantation. Bone Marrow Transplant 11:103, 1993
8. Bensinger WI, Clift R, Martin P, Appelbaum FR, Demirer T, Gooley T, Lilleby K, Rowley S, Sanders J, Storb R, Buckner CD: Allogeneic peripheral blood stem cell transplantation in patients with advanced hematologic malignancies: A retrospective comparison with marrow transplantation. Blood 88:2794, 1996
9. Russel JA, Brown C, Bowen T, Luider J, Ruether JD, Steward D, Chaudhry A, Booth K, Jorgenson K, Coppes MJ, Turner AR, Larratt L, Desai S, Poon M-C, Klassen J: Allogeneic blood cell transplants for hematological malignancy: Preliminary comparison of outcomes with bone marrow transplantation. Bone Marrow Transplant 17:703, 1996
10. Ottinger HD, Beelen DW, Scheulen B, Schaefer UW, Grosse-Wilde H: Improved immune reconstitution after allotransplantation of peripheral blood stem cells instead of bone marrow. Blood 88:2775, 1996
11. Weaver CH, Longin K, Buckner CD, Bensinger W: Lymphocyte content in peripheral blood mononuclear cells collected after the administration of recombinant human granulocyte colony-stimulating factor. Bone Marrow Transplant 13:411, 1994
12. Dreger P, Haferlach T, Eckstein V, Jacobs S, Suttorp M, Löffler H, Müller-Ruchholtz W, Schmitz N: G-CSF-mobilized peripheral blood progenitor cells for allogeneic transplantation: Safety, kinetics of mobilisation, and composition of the graft. Br J Haematol 87:609, 1994
13. dim) and lymphoid subsets, and possible predictors of engraftment and graft-versus-host disease. Blood 86:2842, 1995
14. Dreger P, Suttorp M, Haferlach T, Loeffler H, Schmitz N, Schroyens W: Allogeneic granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells for treatment of engraftment failure after bone marrow transplantation. Blood 81:1404, 1993
15. Anasetti C, Amos D, Beatty PG, Appelbaum FR, Bensinger W, Buckner CD, Clift R, Doney K, Martin PJ, Mickelson E, Nisperos B, O'Quickley J, Ramberg R, Sanders JE, Stewart P, Storb R, Sullivan KM, Witherspoon RP, Thomas ED, Hansen JA: Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia and lymphoma. N Engl J Med 320:197, 1989
16. Beatty PG, Clift RA, Mickelson EM, Nisperos BB, Flournoy N, Martin PJ, Sanders JE, Steward P, Buckner CD, Storb R, Thomas ED, Hansen JA: Marrow transplantation from related donors other than HLA-identical siblings. N Engl J Med 313:765, 1985
17. Ottinger H, Beelen DW, Sayer H, Schaefer UW, Grosse-Wilde H: Bone marrow transplantation from partially HLA-matched related donor in adults with leukaemia: The experience at the University Hospital of Essen, Germany. Br J Haematol 92:913, 1996
18. Beelen DW, Graeven U, Elmaagacli A, Niederle N, Kloke O, Opalka B, Schaefer UW: Prolonged administration of interferon-α in patients with chronic-phase Philadelphia chromosome-positive chronic myelogenous leukemia before allogeneic bone marrow transplantation may adversely affect transplant outcome. Blood 85:2981, 1995
19. Molls M, Quast U, Schaefer UW, Szy D, Beelen DW. Quabeck K, Graeven U, Sayer HG, Sack H: Clinical results and the Essen concept of TBI. Radiother Oncol 18:121, 1990 (suppl)
20. Sayer HG, Beelen DW, Quabeck K, Mohnke M, Oidtmann M, Schaefer UW: Comparison of high-dose busulfan and total-body irradiation prior to allogeneic bone marrow transplantation, in Büchner T, Hiddemann W, Wörmann B, Schellong G, Ritter J (eds): Acute Leukemias IV. Prognostic Factors and Treatment Strategies. Haematology and Blood Transfusion (Vol 36). Berlin, Germany, Springer-Verlag, 1994, p 689
21. Beelen DW, Quabeck K, Kaiser B, Wiefelspütz J, Scheulen ME, Graeven U, Grosse-Wilde H, Sayer HG, Schaefer UW: Six weeks of continuous intravenous cyclosporine and short-course methotrexate as prophylaxis for acute graft-versus-host disease after allogeneic bone marrow transplantation. Transplantation 50:421, 1990
22. Thomas ED, Storb R, Clift RA, Fefer A, Johnson FL, Neimann PE, Lerner K, Glucksberg H, Buckner CD: Bone marrow transplantation (Second of two parts). N Engl J Med 292:895, 1975
23. Glucksberg H, Storb R, Fefer A, Buckner CD, Neiman PE, Clift RA, Lerner KG, Thomas ED: Clinical manifestations of graft-versus-host disease in human recipients of marrow from HLA-matched sibling donors. Transplantation 18:295, 1974
24. Rothe G, Schmitz G, for the Working Group on Flow Cytometry and Image Analysis: Consensus protocol for the flow cytometric immunophenotyping of hematopoietic malignancies. Leukemia 10:877, 1996
25. Elmaacagli AH, Beelen DW, Becks HW, Mobascher A, Stockova J, Trzensky S, Opalka B, Schaefer UW: Molecular studies of chimerism and minimal residual disease after allogeneic peripheral blood progenitor cell or bone marrow transplantation. Bone Marrow Transplant 18:397, 1996
26. Dewald GW, Schad CR, Christensen ER, Law ME, Zinsmeister AR, Stalboerger PG, Jalal SM, Ash RC, Jenkins RB: Fluorescence in situ hybridization with X and Y chromosome probes for cytogenetic studies on bone marrow cells after opposite sex transplantations. Bone Marrow Transplant 12:149, 1993
27. Cole JWL, Grizzle JE: Applications of multivariate analysis of variance to repeated measures experiments. Biometrics 22:810, 1966
28. Kaplan EL, Meier P: Non-parametric estimation from incomplete observations. J Am Stat Assoc 53:457, 1958
29. Cox DR: Regression models and life-tables. J R Stat Soc 34:187, 1992
30. Kernan N: T-cell depletion for prevention of graft-versus-host disease, in Forman SJ, Blume KG, Thomas ED (eds): Bone Marrow Transplantation. Oxford, United Kingdom, Blackwell Scientific Publications, 1994, p 124
31. Miflin G, Russell NH, Hutchinson RM, Morgan G, Potter M, Pagliucy A, Marsh J, Bell A, Milligan D, Lumley M, Cook G, Franklin I: Allogeneic peripheral blood stem cell transplantation for haematological malignancies - An analysis of kinetics of engraftment and GVHD risk. Bone Marrow Transplant 19:9, 1997
32. Schmitz N, Dreger M, Suttorp M, Rohwedder EB, Haferlach T, Löffler H, Hunter A, Russel N: Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by filgrastim (granulocyte colony-stimulating factor). Blood 85:1666, 1995
33. +) in the blood of normal donors. Blood 89:2586, 1997