Meiotic microdeletion breakpoints in the BRCA1 gene are significantly associated with symmetric DNA-sequence elements [4]

American Journal of Human Genetics

Volumn 61, Issue 6, 1997, Pages 1454-1456

  Schmucker, B ^a   Krawczak, M ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

BREAST CANCER; DNA SEQUENCE; GENE DELETION; GENETIC DISTANCE; HUMAN; LETTER; MEIOSIS; PRIORITY JOURNAL;

EID: 0031454599     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/301631     Document Type: Letter

References (6)

1. DN Cooper M Krawczak Human gene mutation 1993 BIOS Scientific Oxford
2. M Krawczak DN Cooper Gene deletions causing human genetic disease: mechanism of mutagenesis and the role of the local DNA sequence environment Hum Genet 86 1991 425 441
3. M Krawczak DN Cooper The human gene mutation database Trends Genet 13 1997 121 122
4. GR Smith Chi hotspots of generalized recombination Cell 34 1983 709 710
5. M Steinmetz Y Uematsu KF Lindahl Hotspots of homologous recombination in mammalian genomes Trends Genet 3 1987 7 10
6. JP Struewing LC Brody MR Erdos RG Kase TR Giambarresi SA Smith FS Collins Detection of eight BRCA1 mutations in 10 breast/ovarian cancer families, including 1 family with male breast cancer Am J Hum Genet 57 1995 1 7