Renin-angiotensin system gene polymorphisms and left ventricular hypertrophy: The case against an association

Advances in Experimental Medicine and Biology

Volumn 432, Issue , 1997, Pages 117-122

  West, M J ^a   Summers, K M ^a   Wong, K K ^a   Burstow, D J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; CHYMASE; DIPEPTIDYL CARBOXYPEPTIDASE;

CONFERENCE PAPER; EVIDENCE BASED MEDICINE; GENETIC POLYMORPHISM; GENOTYPE; HEART LEFT VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR INTERACTION; PREDICTION; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 0031453614     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5385-4_13     Document Type: Conference Paper

References (26)

1. Cambien F, Poirier O, Lecerf L, Evans A, Cambou J-P, Arveiler D, Luc G, Bard J-M, Bara L, Ricard S, Tiret L, Amouyet P, Alhenc-Gelas F, Soubrier F. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992;359:641-644.
2. Schunkert H, Hense H-W, Holmer SR, Stender M, Perz S, Keil U, Lorell BH, Reiger GAJ. Association between a deletion polymorphism of the angiotensin-converting enzyme gene and left ventricular hypertrophy. N EngI J Med 1994;330:1634-1638.
3. Ohishi M, Fujii K, Minamino T, Higaki J, Kamitani A, Rakugi H, Zhao Y, Mikani H, Miki T, Ogihara T. A potent genetic risk factor for restenosis. Nat Genet 1993;5:324-325.
4. Marian AJ, Yu QT, Workman R, Greve G, Roberts R. Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death. Lancet 1993:342:1085-1086.
5. Raynolds MV, Bristow MR, Bush EW, Abraham WT, Lowes BD, Zisman LS, Taft CS, Perryman MB. Angiotensin-converting enzyme DD genotype in patients with ischaemic or dilated cardiomyopathy. Lancet 1993;342:1073-1075.
6. Missouris CG, Barley J, Jeffery S, Carter ND, Singer DRJ, MacGregor GA. Genetic risk for renal artery stenosis: association with deletion polymorphism in angiotensin 1-converting enzyme gene. Kidney Int 1996;49:534-537.
7. Markus HS, Barley J, Lunt R, Bland J, Jeffery S, Carter N, Brown M. Angiotensin-converting enzyme gene deletion polymorphism: a new risk factor for lacunar stroke but not carotid atheroma. Stroke 1995;126:1329-1333.
8. Doria A, Warram JH, Krolewski AS. Genetic predisposition to diabetic nephropathy. Diabetes 1994;43: 690-695.
9. Dahlof B, Pennert K, Hansson L. Reversal of left ventricular hypertrophy in hypertensive patients: meta-analysis of 109 treatment studies. Am J Hypertens 1992;5:95-100.
10. Schunkert H, Dzau VJ, Tang SS, Hirsch AT, Apstein CS, Lorell BH. Increased rat cardiac angiotensin-converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. J Clin Invest 1990;86:1913-1920.
11. Baker KM, Aceto JR Angiotensin II stimulation of protein synthesis and cell growth in chick cells. Am J Physiol 1990; 259(Heart Circ Physiol 28):H610-H618.
12. Dzau VJ, Sasamura H, Hein L. Heterogeneity of angiotensin synthetic pathways and receptor subtypes: physiological and pharmacological implications. J Hyptertens 1993; 11 Suppl 3:S13-8.
13. Phillips MI, Speakman EA, Kimura B. Levels of angiotensin and molecular biology of the tissue renin angiotensin systems. Regul Pept 1993;43:1-20.
14. Klickstein LB, Kaempfer CE, Wintraub BU. The granulocyte-angiotensin system. Angiotensin 1-converting activity of cathepsin G. J Biol Chem 1982;257:15042-6.
15. Tang SS, Loscalzo J, Dzau VJ. Tissue plasminogen activator activates renin angiotensin in vitro. J Vasc Med Biol 1989;1:67-74.
16. Urata H, Nishimura H, Ganten D. Chymase-dependent angiotensin II forming system in humans. Am J Hypertens 1996;9:277-84.
17. Montgomery H, Clarkson P, Dollery C, Prasad K, Losi M-A, Statters D, Jubb M, McEwan J, Humphries S, McKenna W. D polymorphism of the angiotensin-converting enzyme gene is strongly associated with the development of physiological left ventricular hypertrophy. (Abstract.) J Am Coll Cardiol 1996;27(Suppl A):244A.
18. Iwai N, Ohmichi N, Nakamura Y, Kinoshita M. DD genotype of the angiotensin-converting enzyme gene is a risk factor for left ventricular hypertrophy. Circulation 1994;90:2622-2628,
19. Wong KK, Summers KM, Burstow DJ, West MJ. Genetic variants of proteins from the renin angiotension system are associated with pressure load cardiac hypertrophy. Clin Exptl Pharmacol Physiol 1996;23: 587-590.
20. Lindpaintner K, Lee M, Larson MG, Rao S, Pfeffer MA, Ordovas JM, Schaefer EJ, Wilson AF, Wilson PWF, Vasan RS, Myers RH, Levy D. Absence of association or genetic linkage between angiotensin-converting enzyme gene and left ventricular mass. N Engl J Med 1996;334:1023-1028.
21. Kupari M, Perola M, Koskinen P, Virolainen J, Karhunen P. Left ventricular size and function in relation to angiotensin-converting enzyme gene polymorphism in humans. Am J Physiol 1994;267(Heart Circ Physiol 36):H1107-H1111.
22. West MJ, Summers KM, Burstow DJ, Wong KK, Huggard PR. Renin and angiotensin-converting enzyme genotypes in patients with essential hypertension and left ventricular hypertrophy. Clin Exptl Pharmacol Physiol 1994-21:207-210.
23. Jeunemaitre X. Soubrier F, Kotelvtsev YV, et al. Molecular basis of human hypertension: role of angiotensinogen. Cell 1992;71:169-80.
24. West MJ, Wong KK, Summers KM, Burstow DJ. Inability to demonstrate association between markers of angiotensinogen or angiotensin-converting enzyme in hypertensive subjects with different phenotypes of cardiac hypertrophy (abstract). 7th Europ Meeting on Hypertension 1995, P206.
25. Brilla CG, Pick R, Tan LB, Janicki JS, Weber KT. Remodeling of the rat right and left ventricles in experimental hypertension. Circ Res 1990;67:1355-1364.
26. Harrap SB, Dominiczak AF, Fraser R, Lever AF, Morton JJ. Plasma angiotensin II, predisposition to hypertension and left ventricular size in healthy young adults. Circulation 1996;93:1148-1154.