Expression of Na+-H+ exchanger isoforms NHE1 and NHE3 in kidney and blood cells of rabbit and rat

Experimental Nephrology

Volumn 5, Issue 6, 1997, Pages 490-497

  Rutherford, P A ^a,b   Pizzonia, J H ^a   Biemesderfer, D ^a   Abu Alfa, A ^a   Reilly, R ^a   Aronson, P S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WALES   (United Kingdom)

Author keywords

Diabetes mellitus; Erythrocytes; Hydrogen; Hypertension; Kidney; Lithium; Sodium

Indexed keywords

CARRIER PROTEIN; LITHIUM ION; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; PROTON; SODIUM ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD CELL; BRUSH BORDER VESICLE; CONTROLLED STUDY; KIDNEY CORTEX; MEMBRANE VESICLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON SODIUM EXCHANGE; RABBIT; RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BLOOD CELLS; BLOOD PLATELETS; CELL MEMBRANE; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; IMMUNOBLOTTING; KIDNEY; LYMPHOCYTES; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM-HYDROGEN ANTIPORTER;

EID: 0031453418     PISSN: 10187782     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Weder AB: Sodium metabolism, hypertension and diabetes. Am J Med Sci 1994;307(suppl 1): 53-59.
2. Siffert W, Dusing R: Na/H exchange in hypertension and diabetes mellitus: Facts and hypotheses. Basic Res Cardiol 1996;91:179-190.
3. Rutherford PA, Thomas TH, Wilkinson R: Erythrocyte sodium-lithium countertransport: Clinically useful, pathophysiologically instructive or just phenomenology? Clin Sci 1992;82: 341-352.
4. Canessa M, Brugnara C, Escobales N: The Li-Na and Na-K-Cl co-transport systems in essential hypertension. Hypertension 1987; 10-(suppl 1):4-10.
5. Murer H, Hopfer U, Kinne R: Sodium/proton antiport in brush-border membrane vesicles isolated from rat small intestine and kidney. Biochem J 1976;154:597-604.
6. + exchanger isoform NHE-1 in rabbit kidney. Am J Physiol 1992;263: F833-F840.
7. + exchanger isoform of renal brush border. Am J Physiol 1993;265:F736-F742.
8. Wu M-H, Biemesderfer D, Giebisch G, Aronson PS: Role of NHE3 in mediating renal brush border Na-H exchange: Adaptation to metabolic acidosis. J Biol Chem 1996:271:32749-32752.
9. Orlowski J, Kandasamy RA, Shull GE: Molecular cloning of putative members of the Na/H exchanger gene family: cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins. J Biol Chem 1992;267:9331-9339.
10. Tse C-M, Brant SR, Walker MS, Pouyssegur J, Donowitz M: Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na/H exchanger isoform (NHE-3). J Biol Chem 1992;267:9340-9346.
11. 1 renal epithelial cells. Am J Physiol 1991;261: F1088-F1094.
12. +-ATPase: Immunocytochemical localization along nephron segments. Kidney Int 1985;28: 899-913.
13. Aronson PS: Energy-dependence of phlorizin binding to isolated renal microvillus vesicles. J Membr 1978;42:81-98.
14. - co-transport in basolateral membrane vesicles isolated from rabbit renal cortex. J Biol Chem 1986; 261:8778-8783.
15. Dodge JT, Mitchell C, Hanahan D: The preparation and characterisation of haemoglobin free ghosts of human erythrocytes. Arch Biochem Biophys 1963;100:119-130.
16. Peper RJ, Tina WZ, Michelson MM: Purification of lymphocytes and platelets by gradient centrifugation. J Lab Clin Med 1968;72:842-848.
17. Dean WL, Pope JE, Brier ME, Aronoff GR: Platelet calcium transport in hypertension. Hypertension 1994;23:31-37.
18. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-275.
19. Lämmli UK: Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
20. Amemiya M, Loffing J, Lötscher M, Kaissling B, Alpern RJ, Moe OW: Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb. Kidney Int 1995;48:1206-1215.
21. + exchanger in rabbit renal brush border membranes. J Clin Invest 1993;91:2097-2102.
22. Siczkowski M, Davies JE, Ng LL: Activity and density of the Na/H antiporter in normal and transformed human lymphocytes and fibroblasts. Am J Physiol 1994;267:C745-C752.
23. Abu-Alfa A, Biemesderfer D, Pizzonia J, Reilly R, Igarashi P, Aronson PS: Glycosylation of Na-H exchanger isoforms NHE-1 and NHE-3 (abstract). Am Fed Clin Res 1994:317.
24. + countertransport system of mammalian erythrocytes. J Membr Biol 1979;51:263-286.
25. + exchanger. Annu Rev Physiol 1989;47:545-560.
26. Aronson PS: Red cell sodium-lithium countertransport and essential hypertension. N Engl J Med 1986;307:317-332.
27. Weder AB: Red cell Li-Na countertransport and renal lithium clearance in hypertension. N Engl J Med 1986;314:198-201.
28. Cirillo M, Laurenzi M, Panarelli W, Trevisan M, Dyer AR, Stamler R, Stamler J: Sodium-lithium countertransport and blood pressure change over time: The Gubbio Study. Hypertension 1996;27:1305-1311.
29. Carr SJ, Thomas TH, Wilkinson R: Sodium-lithium countertransport activity and its sensitivity to inhibitors with erythrocyte ageing in man. Clin Chim Acta 1988;128:1-8.
30. Brugnara C, Franceschi LD: Effect of cell age and phenylhydrazine on the cation transport properties of rabbit erythrocytes. J Cell Physiol 1993;154:271-280.
31. Kausar S, Phillips JD, Birch NJ: Species differences in lithium-sodium countertransport rate (abstract). Biochem Soc Trans 1991;19:408.