Drug migration from the adhesive matrix to the polymer film laminate facestock in a transdermal nitroglycerin system

Journal of Pharmaceutical and Biomedical Analysis

Volumn 16, Issue 4, 1997, Pages 651-660

  Markovich, Robert J ^a   Taylor, Anne K ^a   Rosen, Jack ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Aluminum metal; Attenuated total reflectance infrared microspectroscopy; High performance liquid chromatography; Nitroglycerine; Transdermal

Indexed keywords

GLYCERYL TRINITRATE;

ARTICLE; DRUG DETERMINATION; DRUG ELIMINATION; DRUG POTENCY; DRUG TRANSPORT; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROPHOTOMETRY; PRIORITY JOURNAL; STORAGE; TECHNIQUE; TRANSDERMAL DRUG ADMINISTRATION;

ADHESIVES; ADMINISTRATION, CUTANEOUS; ALUMINUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIFFUSION; DRUG DELIVERY SYSTEMS; DRUG STABILITY; NITROGLYCERIN; POLYESTERS; SPECTROPHOTOMETRY, INFRARED;

EID: 0031452114     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(97)00069-1     Document Type: Article

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