Adenosine receptor agonists: Synthesis and biological evaluation of the diastereoisomers of 2-(3-hydroxy-3-phenyl-1-propyn-1-yl)NECA

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 12, 1997, Pages 2267-2275

  Camaioni, Emidio ^a   Di Francesco, Emanuela ^a   Vittori, Sauro ^a   Volpini, Rosaria ^a   Cristalli, Gloria ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

Author keywords

Adenosine receptors; Diasteroisomer separation; Nucleosides; Platelet aggregation inhibitors

Indexed keywords

2 (3 HYDROXY 3 PHENYL 1 PROPYN 1 YL) 5' N ETHYLCARBOXAMIDOADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE DERIVATIVE; ADENOSINE RECEPTOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CARDIOVASCULAR EFFECT; DIASTEREOISOMER; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; THROMBOCYTE AGGREGATION;

ADENOSINE; ANIMALS; BLOOD PRESSURE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HEART RATE; MALE; MODELS, MOLECULAR; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; RABBITS; RATS; RATS, INBRED SHR; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P1; STEREOISOMERISM;

EID: 0031450863     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00172-7     Document Type: Article

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