Induction of rat hepatic cytochrome p450 2b subfamily by azidophenobarbital, as a possible photoaffinity probe for the putative phenobarbital receptor: Comparative study with modified phenobarbitals with different functional groups

Drug Metabolism and Disposition

Volumn 25, Issue 12, 1997, Pages 1442-1446

  Oguri, Kazuta ^a   Shinohara, Taishi ^b   Taura, Ken Ichiro ^b   Imamura, Tohru ^b   Yamada, Hideyuki ^b  

^a KYUSHU UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

4 (ACETYLAMINO)PHENOBARBITAL; AMINOPHENOBARBITAL; AZIDOPHENOBARBITAL; CYTOCHROME P450; DRUG RECEPTOR; HYDROXYPHENOBARBITAL; LIGAND; NITROPHENOBARBITAL; OXYGENASE; PHENOBARBITAL DERIVATIVE; TESTOSTERONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INDUCTION; IMMUNOBLOTTING; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; TESTOSTERONE METABOLISM;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; AZIDES; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME ACTIVATION; ENZYME INDUCTION; MALE; MICROSOMES, LIVER; PHENOBARBITAL; PHOTOAFFINITY LABELS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; STEROID HYDROXYLASES;

EID: 0031450311     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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