Euglobals-in-2 and -in-3, new euglobals from Eucalyptus incrassata

Natural Medicines

Volumn 51, Issue 5, 1997, Pages 486-490

  Takasaki, Midori ^a   Konoshima, Takao ^a   Kozuka, Mutsuo ^a   Haruna, Mitsumasa ^b   Ito, Kazuo ^b  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b MEIJO UNIVERSITY   (Japan)

Author keywords

Eucalyplus incrassata; Euglobal In 1; Euglobal In 2; Euglobal In 3; Myrtaceae; Phloroglucinol sesquiterpene

Indexed keywords

EUGLOBAL IN 2; EUGLOBAL IN 3; PHLOROGLUCINOL; SESQUITERPENE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG ISOLATION; ENZYME ACTIVATION; EUCALYPTUS; NONHUMAN; PLANT LEAF; SPECTROSCOPY; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

EID: 0031450259     PISSN: 13403443     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. A part of this work was presented at 37th Symposium on the Chemistry of Natural Products, Tokushima, Oct. 1995. Abstracts of Papers, p. 517.
2. M. Takasaki, T. Konoshima, M. Kozuka, M. Haruna, K. Ito, T. Shingu, Chem. Pharm. Bull., 42, 2591 (1994).
3. T. Konoshima, M. Takasaki, M. Kozuka, T. Nagao, H. Okabe, N. Irino, T. Nakasumi, H. Tokuda, H. Nishino, Biol. Pharm. Bull., 18, 284 (1995), and references cited therein.
4. M. Kokumai, T. Konoshima, M. Kozuka, M. Haruna, K. Ito, J. Nat. Prod., 54, 1082 (1991).
5. M. Takasaki, T. Konoshima, M. Kozuka, M. Haruna, K. Ito, S. Yoshida, Chem. Pharm. Bull., 42, 2177 (1994).
6. M. Takasaki, T. Konoshima, M. Kozuka, M. Haruna, K. Ito, W. D. Crow, D. M. Paton, Chem. Pharm. Bull., 42, 2113 (1994).
7. M. Takasaki, T. Konoshima, M. Kozuka, H. Tokuda, Biol. Pharm. Bull., 18, 435 (1995).
8. The distances between the protons showing significant NOEs and their steric energies were calculated by using the CSC Chem3D plus and MM2 programs (steric energy for view of 1: 46.782 kcal/mol and of 2: 55.190 kcal/mol).
9. LC/APCI-MS were measured under following conditions (Nebrizer temp.: 250°C, Desolvation temp.: 399°C and drift voltage : 50 V).