Potentiative effects of neutral proteinases in an inflamed lung: Relationship of neutrophil procollagenase (proMMP-8) to plasmin, cathepsin G and tryptase in bronchiectasis in vivo

European Respiratory Journal

Volumn 10, Issue 12, 1997, Pages 2788-2793

  Sepper, R ^a,c   Konttinen, Y T ^a,b   Buo L ^d   Eklund, K K ^a,b   Lauhio, A ^b   Sorsa, T ^a   Tschesche, H ^e   Aasen, A O ^d   Sillastu, H ^c  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF TARTU   (Estonia)

^d UNIVERSITY OF OSLO   (Norway)

^e BIELEFELD UNIVERSITY   (Germany)

Author keywords

Bronchiectasis; Cathepsin G; Mast cell tryptase; Plasminogen system; Procollagenase proMMP 8

Indexed keywords

CATHEPSIN G; METALLOPROTEINASE; NEUTRAL PROTEINASE; PLASMIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR; PROCOLLAGENASE; TRYPTASE;

ADOLESCENT; ADULT; ARTICLE; BRONCHIECTASIS; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG LAVAGE; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; PRIORITY JOURNAL; SCHOOL CHILD;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; BIOPSY; BLOTTING, WESTERN; BRONCHIECTASIS; BRONCHOALVEOLAR LAVAGE FLUID; CATHEPSINS; CHYMASES; COLLAGENASES; DOWN-REGULATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; LUNG; MALE; MATRIX METALLOPROTEINASE 8; NEUTROPHIL ACTIVATION; PLASMIN; SERINE ENDOPEPTIDASES; TRYPTASES;

EID: 0031449927     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.97.10122788     Document Type: Article

References (32)

1. Birkedal Hansen H, Moore WG, Bodden MK, et al. Matrix metalloproteinases: a review. Crit Rev Oral Biol Med 1993; 4: 197-250.
2. Springman EB, Angleton EL, Birkedal Hansen H, Van Wart HE. Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation. Proc Natl Acad Sci USA 1990; 87: 364-368.
3. Weiss SJ, Peppin G, Ortiz X, Ragsdale C, Test ST. Oxidalive autoactivation of latent collagenase by human neutrophils. Science 1985; 227: 747-749.
4. Saari H, Suomalainen K, Lindy O, Konttinen YT, Sorsa T. Activation of latent human neutrophil collagenase by reactive oxygen species and serine proteases. Biochem Biophys Res Commun 1990; 171: 979-987.
5. Knäuper V, Kramer S, Reinke H, Tschesche H. Characterization and activation of procollagenase from human polymorphonuclear leucocytes: N-terminal sequence determination of the proenzyme and various proteolytically-activated forms. Eur J Biochem 1990; 189: 295-300.
6. Gruber BL, Schwartz LB, Ramamurthy NS, Irani AM, Marchese MJ. Activation of latent rheumatoid synovial collagenase by human mast cell tryptase. J Immunol 1988; 140: 3936-3942.
7. Stricklin GP, Jeffrey JJ, Roswit WT, Eisen AZ. Human skin procollagenase: mechanism of activation by organomercurials and trypsin. Biochemistry 1983; 22: 61-68.
8. Knäuper V, Wilhelm SM, Seperack PK, et al. Direct activation of human neutrophil procollagenase by recombinant stromelysin. Biochem J 1993; 295: 581-586.
9. Vasalli J, Sappino A, Belin D. The plasminogen activator/ plasmin system. J Clin Invest 1991; 88: 1067-1072.
10. Bertozzi P, Astedt B, Zenziuz L, et al. Depressed bronchoalveolar urokinase activity in patients with adult respiratory distress syndrome. N Engl J Med 1990; 322: 890-897.
11. Stephens RW, P'llanen J, Tapiovaara H, Leung KC, Sim PS, Salonen EM. Activation of prourokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants. J Cell Biol 1989; 108: 1987-1995.
12. Ott U, Pdermatt E, Engel J, Furthmayr H, Timpl R. Protease resistance and conformation of laminin. Eur J Biochem 1982; 123: 63-72.
13. Salonen EM, Saksela O, Vartio T, Vaheri A, Nielsen LS, Zeuthen J. Plasminogen and tissue-type plasminogen activator bind to immobilized fibronectin. J Biol Chem 1985; 260: 12302-12307.
14. Sprengers ED, Kluft C. Plasminogen activator inhibitors. Blood 1987; 69: 381-387.
15. Stockley RA. Bronchiectasis: new therapeutic approaches based on pathogenesis. Clin Chest Med 1987; 8: 481-494.
16. 1-antitrypsin in bronchiectasis. J Clin Immunol 1995; 15: 27-34.
17. Sepper R, Konttinen YT, Ding Y, Sorsa T. Human neutrophil collagenase (MMP-8), identified in bronchiectasis BAL fluid, correlates with severity of disease. Chest 1995; 107: 1641-1647.
18. Cordell JL, Falini B, Erber WN, et al. Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 1984; 32: 219-229.
19. Buø L, Lyberg T, Jorgensen L, Johansen HT, Aasen AO. Location of plasminogen activator (PA) and PA inhibitor in human colorectal adenocarcinomas. APMIS 1993; 101: 235-241.
20. Friberger P. Chromogenic peptide substrates: their use for the assay of factors in the fibrinolytic and the plasma kallikrein-kinin systems. Scand J Clin Lab Invest 1982; 162 (Suppl.): 1-298.
21. Nakajima MC, Powers JC, Ashe BM, Zimmerman M. Mapping of the extended substrate-binding site of cathepsin G and human leukocyte elastase. J Biol Chem 1979; 254: 4027-4032.
22. Lavens SE, Proud D, Warner JA. A sensitive colorimetric assay for the release of tryptase from human lung mast cells in vitro. J Immunol Methods 1993; 166: 93-102.
23. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
24. Towbin H, Staehlin T, Gorden J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1976; 76: 4350-4354.
25. Hsu SM, Raine L, Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981; 29: 577-580.
26. Parton LA, Warburton D, Laug WE. Plasminogen activator inhibitor type 1 production by rat type II pneumocytes in culture. Am J Respir Cell Mol Biol 1992; 6: 133-139.
27. Gunzler WA, Steffens GJ, Otting F, Buse G, Flohe L. Structural relationship between human high and low molecular mass urokinase. Hoppe Seylers Z Physiol Chem 1982; 363: 133-141.
28. Campbell EJ, Senior RM, Welgus HG. Extracellular matrix injury during lung inflammation. Chest 1987; 92: 161-167.
29. Sepper et al. Ann Med 1997 (in press).
30. Gross TJ, Simon R, Kelly CJ, Sitrin RG. Rat alveolar epithelial cells concomitantly express plasminogen activator inhibitor-1 and urokinase. Am J Physiol 1991; 260: L286-L295.
31. 1-antichymotrypsin by oxidatively activated human neutrophil metalloproteinases. J Biol Chem 1992; 267: 5005-5012.
32. Chubinskaya S, Huch K, Mikecz K, et al. Chondrocyte matrix metalloproteinase-8: upregulation by interleukin-1β in human cartilage from knee and ankle joint. Lab Invest 1996; 74: 232-244.