Prolonged deficits in presynaptic serotonin function following withdrawal from chronic cocaine exposure as revealed by 5-HTP-induced head-twitch response in mice

Journal of Neural Transmission

Volumn 104, Issue 11-12, 1997, Pages 1229-1247

  Darmani, N A ^a   Shaddy, J ^b   Elder, E L ^a  

^a A T STILL UNIVERSITY   (United States)

^b TRUMAN STATE UNIVERSITY   (United States)

Author keywords

5 Hydroxytryptophan; Chronic; Cocaine; Deficit; Head twitch response; Withdrawal

Indexed keywords

5 HYDROXYTRYPTOPHAN; COCAINE; SEROTONIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EXPOSURE; HEAD TWITCH; MALE; MOUSE; NEUROCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM;

5-HYDROXYTRYPTOPHAN; ANIMALS; COCAINE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEAD MOVEMENTS; MALE; MICE; MICE, INBRED ICR; RECEPTORS, PRESYNAPTIC; SEROTONIN; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0031448847     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01294723     Document Type: Article

References (47)

1. Batki SL, Manfredi LB, Jacob P, Jones RT (1993) Fluoxetine for cocaine dependence in methadone maintenance: quantitative plasma and urine cocaine/benzoylecgonine concentrations. J Clin Psychopharm 13: 243-250
2. 2 receptor stimulation in rats. Neuropharmacology 35: 295-301
3. Baumann MH, Raley TJ, Partilla JS, Rothman RB (1993) Biosynthesis of dopamine and serotonin in the rat brain after repeated cocaine injections: a microdissection mapping study. Synapse 14: 40-50
4. Baumann MH, Becketts KM, Rothmann RB (1995) Evidence for alterations in presynaptic serotonergic function during withdrawal from chronic cocaine in rats. Eur J Pharmacol 282: 87-93
5. Black EW, Lakoski JM (1990) In vitro electrophysiology of dorsal raphe serotonergic neurons in subchronic cocaine-treated rats: development of tolerance to acute cocaine administration. Mol Cell Neurosci 1: 84-91
6. Bradberry CW, Nobiletti JB, Elsworth JD, Murphy D, Jatlow P, Roth RH (1993) Cocaine and cocalthylene: microdialysis comparison of brain drug levels and effects on dopamine and serotonin. J Neurochem 60: 1429-1435
7. Broderick PA, Kornak EP, Eng F, Wechler R (1993) Real time detection of acute (IP) cocaine-enhanced dopamine and serotonin release in ventrolateral nucleus accumbens of behaving Norway rat. Pharmacol Biochem Behav 46: 715-722
8. Buckland PR. Spurlock G, McGuffin P (1996) Amphetamine and vigabatrin down-regulate aromatic L-amino acid decarboxylase mRNA levels. Brain Res Mol: Brain Res 35: 69-76
9. Carroll ME, Lac ST, Asencio M, Kargh R (1990) Fluoxetine reduces intravenous cocaine self-administration in rats. Pharmacol Biochem Behav 35: 237-244
10. Cunningham KA (1995) Modulation of serotonin function by acute and chronic cocaine: neurophysiological analysis: In: Hammer RP Jr (ed) The neurobiology of cocaine: cellular and molecular mechanisms. CRC Press, Boca Raton Fl, pp 121-123
11. Cunningham KA, Callahan PM (1991) Monoamine reuptake inhibitors enhance the discriminative state induced by cocaine in the rat. Psychopharmacology 104: 177-180
12. Cunningham KA, Paris JM, Goeders NE (1992) Serotonin neurotransmission in cocaine sensitization. Ann NY Acad Sci 654: 117-127
13. Darmani NA (1996) Differential potentiation of L-tryptophan-induced head-twitch response in mice by cocaine and sertraline. Life Sci 59: 1109-1119
14. Darmani NA (1997a) Cocaine and selective monoamine uptake blockers (sertraline, nisoxetine and GBR 12935) prevent the d-fenfluramine-induced head-twitch response in mice. Pharmacol Biochem Behav (in press)
15. Darmani NA (1997b) Withdrawal from chronic cocaine administration causes prolonged deficits in L-tryptophan-induced head-twitch response in mice. Life Sci 61: 1147-1158
16. Darmani NA (1997c) Deficits in d-fenfluramine-sensitive pool of brain 5-HT following withdrawal from chronic cocaine exposure. Life Sci 61: 2575-2582
17. 1A-receptor function. Pharmacol Biochem Behav 55: 387-396
18. Darmani NA, Hadfield MG, Carter WH, Martin BR (1990) Acute and chronic effects of cocaine on isolation-induced aggression. Psychopharmacology 102: 37-40
19. 1A receptors. Pharmacol Biochem Behav 38: 353-357
20. 2-receptor function. Pharmacol Biochem Behav 41: 519-527
21. Darmani NA, Shaddy J, Gerdes CF (1996) Differential ontogenic regulation of three DOI-induced behaviours in mice. Physiol Behav 60: 1495-1500
22. Dworkin SI, Co C, Smith JE (1995) Rat brain neurotransmitter turnover rates altered during withdrawal from chronic cocaine administration. Brain Res 682: 116-126
23. Eble JP, Goodrich C (1987) The maturational onset of the 5-HT mediated head twitch in mice. Physiol Behav 41: 47-51
24. Fibiger HC, Miller JJ (1977) An anatomical and electrophysiological investigation of the serotonergic projection from the dorsal raphe nucleus to the substantia nigra in the rat. Neuroscience 2: 975-987
25. Gartside SE, Cowen PJ, Sharp T (1992) Effect of 5-hydroxy-L-tryptophan on the release of 5-HT in rat hypothalamus in vivo as measured by microdialysis. Neuropharmacology 31: 9-14
26. Heal DJ, Luscombe GP, Martin KF (1992) Pharmacological characterization of 5-HT receptor subtypes using behavioral models. In: Marsden CA, Heal DJ (eds) Central serotonin receptors and psychotropic drugs. Blackwell, London, pp 56-99
27. 2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat striatum. Brain Res 698: 204-208
28. Johanson CE, Fischman MW (1989) The pharmacology of cocaine related to its abuse. Pharmacol Rev 41: 3-52
29. Kosten TA, Kosten TR, Gawin FH, Gorden LT, Hogan IS, Kleber HD (1992) An open trial of sertraline for cocaine abuse. Am J Addict 1: 349-353
30. Knapp S, Mandell AJ (1972) Narcotic drues: effects on the serotonin biosynthetic systems of the brain. Science 177: 1209-1211
31. Kuhar MJ, Pilotte NS (1996) Neurochemical changes in cocaine withdrawal. Trends Pharmacol Sci 17: 260-264
32. Levy AD, Rittenhouse PA, Li Q, Bonnadonna AM, Alvarez Sanz MC, Kerr JE, Betha CL, Van de Kar LD (1992) Repeated injections of cocaine inhibit the serotonergic regulation of prolactin and renin secretion in rats. Brain Res 580: 6-11
33. 1A agonist, 8-OH-DPAT. Neuropharmacology 33: 335-342
34. Loh EA, Roberts DCS (1990) Break-points on a progressive ratio schedule reinforced by intravenous cocaine increase following depletion of forebrain serotonin. Psychopharmacology 101: 262-266
35. Moore RY, Halaris AE, Jones BE (1978) Serotonin neurons of the midbrain raphe: ascending projections. J Comp Neurol 180: 417-438
36. Murphy DL (1991) An overview of serotonin neurochemistry and neuroanatomy. In: Sandler M, Cooper A, Harnet S (eds) 5-Hydroxytryptamine in psychiatry: a spectrum of ideas. Oxford University Press, Oxford, pp 23-26
37. 3 mediated control of dopaminergic function. Psychopharmacology 112 [Suppl 1]: S60-S67
38. Parsons LH, Justice JB Jr (1993) Perfusate serotonin increases extracellular dopamine in the nucleus accumbens as measured by in vivo microdialysis. Brain Res 606: 195-199
39. Parsons LH, Koob GF, Weiss F (1995) Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine. J Pharmacol Exp Ther 274: 1182-1191
40. Peltier R, Schenk S (1993) Effects of serotonergic manipulations on cocaine self-administration in rats. Psychopharmacology 110: 390-394
41. Pollack MH, Rosenbaum JF (1991) Fluoxetine treatment of cocaine abuse in heroin addicts. J Clin Psychiat 52: 31-33
42. Ritz MC, Cone EJ, Kuhar MJ (1990) Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study. Life Sci 46: 635-645
43. Roberts DCS, Loh EA, Baker GB, Vickers G (1994) Lesions of central serotonin system affect responding on a progressive ratio schedule reinforced by intravenous cocaine or by food. Pharmacol Biochem Behav 49: 177-182
44. Spealman RD (1993) Modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys. Psychopharmacology 112: 93-99
45. Walsh SL, Prestin KL, Sullivan JT, Fromne R, Bigelow GE (1994) Fluoxetine alters the effects of intravenous cocaine in humans. J Clin Psychopharm 14: 396-407
46. Weiss F, Parsons LH, Markou A (1995) Neurochemistry of cocaine withdrawal. In: Hammer RP Jr (ed) The neurobiology of cocaine: cellular and molecular mechanisms. CRC Press, Boca Raton, pp 163-180
47. Yocca FD, Wright RN, Margraf RR, Eison AS (1990) 8-OH DPAT and buspirone analogs inhibit the ketanserin-sensitive quipazine-induced head shake response in rats. Pharmacol Biochem Behav 35: 1-4