Is FISH painting an appropriate biological marker for dose estimates of suspected accidental radiation overexposure? A review of cases investigated in France from 1995 to 1996

Environmental Health Perspectives

Volumn 105, Issue SUPPL. 6, 1997, Pages 1427-1432

  Sorokine Durm, Irène ^a   Durand, Valérie ^a   Roy, Annie Le ^a   Paillole, Nathalie ^a   Roy, Laurence ^a   Voisin, Philippe ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

Author keywords

Chromosomal aberrations; Conventional; Cytogenetics; Dosimetry; FISH painting; Suspected radiation overexposure

Indexed keywords

BIOLOGICAL MARKER; COBALT 60;

CALIBRATION; CHROMOSOME ABERRATION; CHROMOSOME PAINTING; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOGENETICS; DNA DAMAGE; DNA PROBE; DOSIMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; FRANCE; HUMAN; HUMAN CELL; METAPHASE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; RADIATION ACCIDENT; RADIATION EXPOSURE; RECIPROCAL CHROMOSOME TRANSLOCATION; STRUCTURAL CHROMOSOME ABERRATION;

EID: 0031444958     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.97105s61427     Document Type: Conference Paper

References (21)

1. IAEA. Biological Dosimetry: Chromosomal Aberration Analysis for Dose Assessment. Tech Rpt Ser No 260. Vienna:International Atomic Energy Agency, 1986.
2. Bender MA, Awa AA, Brooks AL, Evans HJ, Groer PG, Littlefield G, Pereira C, Preston RJ, Wachholz BW. Current status of cytogenetics procedures to detect and quantify previous exposure to radiation. Mutat Res 196:103-159 (1988).
3. Awa A, Sofuni T, Honda T, Itoh N, Neriishi S, Otake M. Relationship between the radiation dose and chromosome aberrations in atomic bomb survivors of Hiroshima and Nagasaki. J Radiat Res 19:126-140 (1978).
4. Bauchinger M, Schmid E, Braselmann H, Willich N, Clemm C. Time-effect relationship of chromosome aberrations in peripheral lymphocytes after radiation therapy for seminoma. Mutat Res 211:265-272 (1989).
5. Pinkel D, Straume T, Gray JW. Cytogenetics analysis using quantitative high-sensitivity fluorescence hybridization. Proc Natl Acad Sci USA 83:2934-2938 (1986).
6. Lucas JN, Tenjin T, Straume T, Pinkel D, Moore D II, Litt M, Gray JW. Rapid human chromosome aberration analysis using fluorescence in situ hybridization. Int J Radiat Biol 56:35-44 (1989).
7. Lucas JN, Awa A, Straume T, Poggensee M, Kodama Y, Nakano M, Ohtaki K, Weier H-U, PinkelD, Gray J et al. Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation. Int J Radiat Biol 62:53-63 (1992).
8. Cremer C, Cremer T. Analysis of chromosomes in molecular tumor and radiation cytogenetics: approaches, applications and perspectives. Eur J Histocnem 36:15-25 (1991).
9. Lichter P, Boyle AC, Cremer T, Ward DC. Analysis of genes and chromosomes by non-isotopic in situ hybridization. Genet Anal Tech Appl 8:24-35 (1991).
10. Nararajan AT, Vyas RC, Darroudi F, Vermeulen S. Frequencies of X-ray-induced chromosome translocations in human peripheral lymphocytes as detected by in situ hybridization using chromosome-specific DNA libraries. Int J Radiat Biol 61:199-203 (1992).
11. Gray JW, Pinkel D, Brown JM. Fluorescence in situ hybridization in cancer and radiation biology. Radiat Res 137:275-289 (1994).
12. Finnon P, Lloyd DC, Edwards AA. Fluorescence in situ hybridization detection of chromosomal aberrations in human lymphocytes: applicability to biological dosimetry. Int J Radiat Biol 68:429-435 (1995).
13. Tucker JD, Morgan WF, Awa AA, Bauchinger M, Blakey D, Cornforth M, Littlefield LG, Natarajan AT, Shasserre C. A proposed system for scoring structural aberrations detected by chromosome painting. Cytogenet Cell Genet 6:211-221 (1995).
14. Tucker JD, Lee DA, Moore II DH. Validation of chromosome painting. II: A detailed analysis of aberrations following high doses of ionizing radiation in vitro. Int J Radiat Biol 67:19-28 (1995).
15. Chung HW, Ryu EK, Kim YJ, Ha SW. Chromosome aberrations in workers of nuclear-power plants. Mutat Res 350:307-314 (1996).
16. Knehr S, Zitzelsberger H, Braselmann H, Nahrstedt U, Bauchinger M. Chromosome analysis by fluorescence in situ hybridization: further indications for a non-DNA-proportional involvement of single chromosome in radiation-induced structural aberrations. Int J Radiat Biol 70:385-392 (1996).
17. Moore DH II, Epstein L, Reeder J, Wheeless L, Waldman FM, NCI Bladder Tumor Marker Network. Interlaboratory variability in fluorescence in situ hybridization. Cytometry 25:125-132 (1996).
18. Savage JRK, Simpson PJ. FISH "painting" patterns resulting from complex exchanges. Mutat Res 312:51-60 (1994).
19. Tanaka K, Poop S, Fisher C, Van Kaicks G, Kamada N, Cremer T, Cremer C. Chromosome aberration analysis in atomic bomb survivors and Thorotrast patient using two- and three-colour chromosome painting of chromosomal subsets. Int J Radiat Biol 70:95-108 (1996).
20. Lucas JN, Chen AM, Sachs RK. Theoretical predictions on the equality of radiation-produced dicentrics and translocations detected by chromosome painting. Int J Radiat Biol 69:145-153 (1996).
21. Chung HW, Ryu EK, Kim YJ, Ha SW. Chromosome aberrations in workers of nuclear-power plants. Mutat Res 350:307-314 (1996).