Terminal complement complexes induce cell cycle entry in oligodendrocytes through mitogen activated protein kinase pathway

Immunopharmacology

Volumn 38, Issue 1-2, 1997, Pages 177-187

  Rus, Horea ^a   Niculescu, Florin ^a   Badea, Tudor ^a   Shin, Moon L ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Cell cycle; Complement activation; Mitogen activated protein kinases; Oligodendrocytes; Oncogenes

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; COMPLEMENT MEMBRANE ATTACK COMPLEX; DNA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL CYCLE; CONTROLLED STUDY; DNA SYNTHESIS; GENE EXPRESSION; NONHUMAN; OLIGODENDROGLIA; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL; RAT;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL CYCLE; COMPLEMENT ACTIVATION; COMPLEMENT MEMBRANE ATTACK COMPLEX; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; GENES, JUN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; OLIGODENDROGLIA; PROTO-ONCOGENE PROTEINS C-RAF; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STEM CELLS;

EID: 0031444894     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-3109(97)00063-5     Document Type: Article

References (46)

1. Benzaquen, L.R., Nicholson-Weller, A., Halperin, J.A., 1994. Terminal complement proteins C5b-9 release basic fibroblust growth factor and platelet-derived growth factor from endothelial cells. J. Exp. Med. 179, 985-992.
2. Boulton, T.G., Zhong, Z., Wen, Z., Darnell, J.E. Jr., Stahl, N., Yancopoulos, G.D., 1995. STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase. Proc. Natl. Acad. Sci. USA 92, 6915-6919.
3. Carney, D.F., Lang, T.J., Shin, ML., 1990. Multiple signal messengers generated by terminal complement complexes and their role in terminal complement complex elimination. J. Immunol. 145, 623-629.
4. Cavigelli, M., Dolfi, F., Claret, F.X., Karin, M., 1995. Induction of c-fos expression through JNK-mediated TCF/ELK-1 phosphorylation. EMBO J. 14, 5957-5964.
5. Chirgwin, J.M., Przybyla, A.E., MacDonald, R.J., Rutter, W.J., 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18, 5294-5299.
6. Compston, D.A., Morgan, B.P., Oleesky, D., Fifield, R., Campbell, A.K., 1986. Cerebrospinal fluid C9 in demyelinating disease. Neurology 36, 1503-1506.
7. Compston, D.A., Morgan, B.P., Campbell, A.K., Wilkins, P., Cole, G., Thomas, N.D., Jasani, B., 1989. Immunocytochemical localization of the terminal complement complex in multiple sclerosis. Neuropathol. Appl. Neurohiol. 15, 307-316.
8. Coso, O.A., Chiariello, M., Kalinec, G., Kyriakis, J.M., Woodgett, J., Gutkind, J.S., 1995. Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway. J. Biol. Chem. 270, 5620-5624.
9. Crespo, P., Xu, N., Simonds, W.F., Gutkind, J.S., 1994a. Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits. Nature 369, 418-420.
10. Crespo, P., Xu, N., Daniotti, J.L., Troppmair, J., Rapp, U.R., Gutkind, J.S., 1994b. Signaling through transforming G protein-coupled receptors in NIH 3T3 cells involves c-raf activation. Evidence for a protein kinase C-independent pathway. J. Biol. Chem. 269, 21103-21109.
11. Cyong, J.C., Witkin, S.S., Rieger, B., Barbarese, E., Good, R.A., Day, N.K., 1982. Antibody-independent complement activation by myelin via the classical complement pathway. J. Exp. Med. 155, 587-598.
12. DiScipio, R.G., Smith, C.A., Müller-Eberhard, H.J., Hugh, T.E., 1983. The activation of human complement component C5 by a fluid phase C5 convertase. J. Biol. Chem. 258, 10629-10636.
13. Edelmann, H.M., Kühne, C., Petritsch, C., Ballou, L.M., 1996. Cell cycle regulation of p70 S6 kinase and p42/p44 mitogenactivated protein kinases in Swiss mouse 3T3 fibroblasts. J. Biol. Chem. 271, 963-971.
14. Evans, S.W., Farrar, W.L., 1987. Interleukin 2 and diacylglycerol stimulate phosphorylation of 40 S ribosomal S6 protein. Correlation with increased protein synthesis and S6 kinase activation. J. Biol. Chem. 262, 4624-4630.
15. Gardner, A.M., Lange-Carter, C.A., Vaillancourt, R.R., Johnson, G.L., 1994. Measuring activation of kinases in mitogen-activated protein kinase regulatory network. Methods Enzymol. 238, 258-270.
16. Halperin, J.A., Taratuska, A., Nicholson-Weller, A., 1993. Terminal complement complex C5b-9 stimulates mitogenesis in 3T3 cells. J. Clin. Invest. 91, 1974-1978.
17. Hawes. B.E., van Biesen, T., Koch, W.J., Luttrell, L.M., Lefkowitz, R.J., 1995. Distinct pathways of Gi-and Gq-mediated mitogen-activated protein kinase activation. J. Biol. Chem. 270, 17148-17153.
18. 2+ signaling and a new class of inhibitors. Methods Enzymol. 139, 570-582.
19. Hill, C.S., Treisman, R., 1995. Transcriptional regulation by extracellular signals: Mechanisms and specificity. Cell 80, 199-211.
20. Janknech, R., Hunter, T., 1997. Activation of Sap la transcription factor by the c-jun N-terminal kinase (JNK) mitogen-activated protein kinase. J. Biol. Chem. 272, 4219-4224.
21. Lang, T.J., Badea, T.C., Wade, R., Shin, M.L., 1997. Sublytic terminal complement attack on myotubes decreased the expression of mRNAs encoding muscle-specific proteins. J. Neurochem. 68, 1581-1589.
22. Lazar, D.F., Wiese, R.J., Brady, M.J., Mastick, C.C., Waters, S.B., Yamauchi, K., Pessin, J.E., Cuatrecasas, P., Saltiel, A.R., 1995. Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin. J. Biol. Chem. 270, 20801-20807.
23. Linington, C., Morgan, B.P., Scolding, N.J., Wilkins, P., Piddlesden, S., Compston, D.A., I989a. The role of complement in the pathogenesis of experimental allergic encephalomyelitis. Brain 112, 895-911.
24. Linington, C., Lassmann, H., Morgan, B.P., Compston, D.A., 1989b. Immunohistochemical localization of terminal complement component C9 in experimental allergic encephalomyelitis. Acta Neuropathol. 79, 78-85.
25. Lovett, D.H., Haensch, G.M., Goppelt, M., Resch, K., Gemsa, D., 1987. Activation of glomerular mesangial cells by the terminal membrane attack complex of complement. J. Immunol. 138, 2473-2480.
26. Marshall, C.J., 1995. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185.
27. Müller-Eberhard, H.J., 1988. Molecular organization and function of the complement system. Ann. Rev. Biochern. 57, 321-347.
28. Niculescu, F., Rus, H., Shin, S., Lang. T., Shin, M.L., 1993. Generation of diacylglycerol and ceramide during homologous complement activation. J. Immunol. 150, 214-224.
29. Niculescu, F., Rus, H., Shin, M.L., 1994. Receptor-independent activation of guanine nucleotide-binding regulatory proteins by terminal complement complexes. J. Biol. Chem. 269, 4417-4423.
30. Niculescu, F., Rus, H., van Biesen, T., Shin, M.L., 1997. Activation of Ras and mitogen-activated protein kinase pathway by terminal complement complexes is G protein dependent. J. Immunol. 158, 4405-4412.
31. Piddlesden, S.J., Storch, M.K., Hibbs, M., Freeman, A.M., Lassmann, H., Morgan, B.P., 1994. Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis. J. Immunol. 152, 5477-5484.
32. Rus, H.G., Niculescu, F., Shin, M.L., 1996. Sublytic complement attack induces cell cycle in oligodendrocytes. S phase induction is dependent on c-jun activation. J. Immunol. 156, 4892-4900.
33. Sanders, M.E., Koski, C.L., Robbins, D., Shin, M.L., Frank, M.M., Joiner, K.A., 1986. Activated terminal complement in cerebrospinal fluid in Guillain-Barré syndrome and multiple sclerosis. J. Immunol. 136, 4456-4459.
34. Scolding, N.J., Morgan, B.P., Houston, A., Campbell, A.K., Linington, C., Compston. D.A.S., 1989. Normal rat serum cytotoxicity against syngeneic oligodendrocytes. J. Neurol. Sci. 89, 289-300.
35. Shearer, W.T., Atkinson, J.P., Frank, M.M., Parker, C.W., 1975. Humoral immunostimulation. IV. Role of complement. J. Exp. Med. 141, 736-752.
36. Shin, M.L., Rus, H.G., Niculescu, F.I., 1996. Membrane attack by complement: Assembly and biology of terminal complement complexes. In: Lee, A.K. (Ed.), Biomembranes, vol. 4. JAI Press Inc. Greenwich, CT, pp. 123-149.
37. 4 from sublethally injured oligodendrocytes by terminal complement complexes. J. Neurochem. 48, 271-278.
38. Shirazi, Y., Rus, H.G., Macklin, W.B., Shin, ML., 1993. Enhanced degradation of messenger RNA encoding myelin protein by terminal complement complexes in oligodendrocytes. J. Immunol. 150, 4581-4590.
39. Sims, P.J., Rollins, S.A., Wiedmer, T., 1989. Regulatory control of complement on blood platelets. Modulation of platelet procoagulant responses by a membrane inhibitor of the C5b-9 complex. J. Biol. Chem. 264, 19228-19235.
40. Thomas, P., 1980. Hybridization of denatured RNA and small DNA fragments to nitrocellulose. Proc. Natl. Acad. Sci. USA 77, 5201-5204.
41. Treisman, R., 1996. Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol. 8, 205-215.
42. Vaillancourt, R.R., Harwood, A.E., Winitz, S., 1994. Analysis of guanine nucleotides associated with protooncogene ras. Methods Enzymol. 238, 255-258.
43. Vanguri, P., Silverman, B.A., Koski, C.L., Shin, M.L., 1982. Complement activation by isolated myelin: Activation of the classical pathway in the absence of myelin-specific antibodies. Proc. Natl. Acad. Sci. USA 79, 3290-3294.
44. Vanguri, P., Shin, M.L., 1988. Hydrolysis of myelin basic protein in human myelin by terminal complement complexes. J. Biol. Chem. 263, 7228-7234.
45. Wren, D.R., Noble, M., 1989. Oligodendrocytes and oligodendrocyte/type-2 astrocyte progenitor cells of adult rats are specifically susceptible to the lytic effects of complement in absence of antibody. Proc. Natl. Acad. Sci. USA 86, 9025-9029.
46. Ueda, Y., Hirai, S.I., Osada, S.I., Suzuki, A., Mizuno, K., Ohno, S., 1996. Protein kinase C δ activates the MEK-ERK pathway in a manner independent of Ras and dependent of Raf. J. Biol. Chem. 271, 23512-23519.