Platelet aggregation and neutrophil sequestration in the mesenteric circulation in inflammatory bowel disease

European Journal of Gastroenterology and Hepatology

Volumn 9, Issue 12, 1997, Pages 1213-1217

  Collins, Carole E ^a,b   Rampton, David S ^a   Rogers, John ^a   Williams, Norman S ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b ST MARY S HOSPITAL   (United Kingdom)

Author keywords

Crohn's disease; Inflammatory bowel disease; Mesenteric microvascular thrombosis; Neutrophil; Platelet aggregation; Ulcerative colitis

Indexed keywords

ADULT; AGED; ARTERIAL BLOOD; ARTICLE; CELL MIGRATION; CLINICAL ARTICLE; COLON BIOPSY; COLON MUCOSA; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; FEMALE; HUMAN; HUMAN CELL; LEUKOCYTE DIFFERENTIAL COUNT; MALE; MESENTERIC ARTERY; MESENTERIC VEIN; MESENTERY BLOOD FLOW; MICROTHROMBUS; NEUTROPHIL; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOGENESIS; ULCERATIVE COLITIS; VENOUS BLOOD;

ADULT; AGED; COLITIS, ULCERATIVE; CROHN DISEASE; FEMALE; HUMANS; INFLAMMATORY BOWEL DISEASES; LEUKOCYTE COUNT; MALE; MESENTERIC ARTERIES; MESENTERIC VEINS; MIDDLE AGED; NEUTROPHILS; PLATELET AGGREGATION; PLATELET COUNT;

EID: 0031444861     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Wakefield AJ, Sawyerr AM, Dhillon AP, et al.: Pathogenesis of Crohn's disease: multifocal gastrointestinal infarction. Lancet 1989, ii:1057-1062.
2. Donnellan WL: Early histological changes in ulcerative colitis. Gastroenterology 1996, 50:519-540.
3. Dhillon AP, Anthony A, Sim R, et al.: Mucosal capillary thrombi in rectal biopsies. Histopathology 1992, 21:127-133.
4. Webberley MJ, Hart MT, Melikian V: Thromboembolism in inflammatory bowel disease: role of platelets. Gut 1993, 34:247-251.
5. Collins CE, Cahill MR, Newland AC, et al.: Platelets circulate in an activated state in inflammatory bowel disease. Gastroenterology 1994, 106:840-845.
6. Weksler BB: Platelets. In Inflammation: Basic Principles and Clinical Correlates, 2nd edn. Edited by Gallin JI, Goldstein IM, Snyderman R. Now York: Raven Press; 1992:727-746.
7. Wu KK, Hoak JC: A new method for the quantitative detection of platelet aggregates in patients with arterial insufficiency. Lancet 1974, ii:924-926.
8. Kohanna FH, Smith MH, Salzman EW: Do patients with thromboembolic disease have circulating platelet aggregates? Blood 1984, 64:205-209.
9. Diem K, Seldrup J: Volume 2: introduction to statistics, statistical tables and mathematical formulae. In Geigy Scientific Tables, 8th edn. Edited by Lentner C. Basle, Switzerland: Ciba-Geigy; 1982:207.
10. Saverymuttu SH, Camilleri M, Rees H, et al.: Indium 111-granulocyte scanning in the assessment of disease extent and disease activity in inflammatory bowel disease. Gastroenterology 1986, 90:1121-1128.
11. Collins CE, Rampton DS: Platelet dysfunction: a new dimension in inflammatory bowel disease. Gut 1995, 36:5-8.
12. Stevens TRJ, James JP, Simmonds NJ, et al.: Circulating von Willebrand factor in inflammatory bowel disease. Gut 1992, 33:502-506.
13. Swan CHJ, Williams JS, Cooke WT: Fibrinolysis in colonic disease. Gut 1970, 11:588-591.