Detection of major genes underlying several quantitative traits associated with a common disease using different ascertainment schemes

Genetic Epidemiology

Volumn 14, Issue 6, 1997, Pages 809-814

  Iyengar, Sudha ^a   Calafell, Francesc ^a   Kidd, Kenneth K ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Complex disease; Extremely discordant sib pairs; Quantitative trait loci

Indexed keywords

ADULT; CHROMOSOME 4; CHROMOSOME 5; CHROMOSOME 8; CHROMOSOME MAP; CONFERENCE PAPER; EPISTASIS; FAMILY; FEMALE; GENE FREQUENCY; GENE LOCATION; GENETIC LINKAGE; HUMAN; MAJOR CLINICAL STUDY; MAJOR GENE; MALE; QUANTITATIVE TRAIT; REGRESSION ANALYSIS; SIBLING; VARIANCE;

CHROMOSOME MAPPING; EPISTASIS, GENETIC; FEMALE; GENE FREQUENCY; GENETIC DISEASES, INBORN; GENETIC MARKERS; HUMANS; LINKAGE (GENETICS); MALE; MATCHED-PAIR ANALYSIS; NUCLEAR FAMILY; PREDICTIVE VALUE OF TESTS; QUANTITATIVE TRAIT, HERITABLE;

EID: 0031444118     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(1997)14:6<809::AID-GEPI41>3.0.CO;2-R     Document Type: Conference Paper

References (5)

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2. Eaves L, Meyer J (1994): Locating human quantitative trait loci: guidelines for the selection of sibling pairs for genotyping. Behav Genet 24:443-455.
3. Kruglyak L, Lander ES (1995): Complete multipoint sib-pair analysis of qualitative and quantitative traits. Am J Hum Genet 57:439-454.
4. Lander E, Kruglyak L (1995): Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247.
5. Risch N, Zhang H (1995). Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 268:1584-1589.