Assessment of mutagenic potential of propoxur and its modulation by indole-3-carbinol

Food and Chemical Toxicology

Volumn 35, Issue 10-11, 1997, Pages 1081-1084

  Agrawal, R C ^a   Mehrotra, N K ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Bone marrow; Indole 3 carbinol; Micronucleus; Propoxur

Indexed keywords

3 INDOLEMETHANOL; ANTIMUTAGENIC AGENT; PROPOXUR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MICRONUCLEUS TEST; MOUSE; MUTAGEN TESTING; MUTAGENICITY; NONHUMAN; ORAL DRUG ADMINISTRATION;

ANIMALIA;

EID: 0031442601     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(97)87275-4     Document Type: Article

References (22)

1. Arroyo S. G., Calderson-Segura M. E. and Rafal V. P. (1995) Sister chromatid exchange in human lymphocytes induced by propoxur following plant activation by Vicia faba. Environmental and Molecular Mutagenesis 26, 324-330.
2. 3C differentially modulated, mediated steroid hydroxylase activities in P-450 mice. Chemico-Biological Interactions 83, 155-169.
3. Eisenbrand G., Ungerel O. and Preussmann R. (1974a) Rapid formation of carcinogenic N-nitrosamine by interaction of nitrite with fungicide derived from dithiocarbamic acid in vitro under simulated gastric conditions and in vivo in the rat stomach. Food and Cosmetics Toxicology 12, 229-232.
4. Gonzalez C. M., Loria D. and Matos F. (1990) Genotoxicity of the pesticide propoxur and its nitroso derivative, no-propoxur on human lymphocyte in vitro. Mutation Research 232, 45-48.
5. Graham S., Dayal H., Swansan A., Mittelman A. and Wilkinsan G. (1978) Diet in the epidemiology of cancer of the colon and rectum. Journal of the National Cancer Institute 61, 709-714.
6. Grichner T., Badaev S. A., Pospisil F. and Velminsky J. (1990) Effect of humic acids, para aminobenzoic acid and ascorbic acid on the N-nitrosation of carbamate insecticide propoxur and on the mutagenicity of nitroso propoxur. Mutation Research 229, 37-41.
7. Lijinsky W. and Elespuru R. (1976) Mutagenicity of N-nitroso derivatives of carbamate insecticides. In Environmental-N-Nitroso Compounds Analysis and Formation. Edited by E. A. Walker, P. Bogowsky and L. Griciute. pp. 425-428. IARC Scientific Publications no. 14. International Agency for Research on Cancer, Lyon.
8. McDanell R., McLean A. E. M., Hanley A. B., Heanly R. K. and Fenwick G. R. (1988) Chemical and biological properties of indole glucosinolates (glucobrassicin). A review. Food and Chemical Toxicology 26, 59-70.
9. Marchand L. L., Yoswizawa C. N., Kolonel L. N., Hankin J. H. and Godman M. T. (1989) Vegetable consumption and lung cancer risk. A population-based case control study in Hawaii. Journal of the National Cancer Institute 89, 1158-1164.
10. Schimid W. (1975) The micronucleus test. Mutation Research 31, 9-15.
11. Seiler J. P. (1977) Nitrosation in vitro and in vivo by sodium nitrite and mutagenicity of nitrogenous pesticides. Mutation Research 48, 225-236.
12. Shertzer H. G. and Sainsbury M. (1991) Intrinsic acute toxicity and hepatic enzyme inducing properties of the chemoprotectants indole-3-carbinol and 5,10-dihydroindenol [1,2b]indole in mice. Food and Chemical Toxicology 29, 237-249.
13. Siebert D. and Lemperle E. (1974) Induction of mitotic gene conversion in Saccharomyces cervisiae by N-nitroso pesticides. Mutation Research 22, 121-126.
14. Sojak S. (1977) The effect of isopropoxyphenyl-N-methyl-N-nitrosocarbamate on barley. Gen Slecht 13, 223-230.
15. Sparnins V. L., Mott A. W., Barany G. and Waternberg L. W. (1986) Effect of allyl methyl trisulfide on glutathione S-transferase activity and B(a)P induced neoplasia in mice. Nutrition and Cancer 8, 211-215.
16. Sumer S., Diril N. and Isbirank A. (1990) The mutagenicity of some insecticides in the salmonella/microsome test system. Mikrobiyoloji Bulteni 24, 103-110.
17. Tomlin C. (Editor) (1994) The Pesticide Manual. British Crop Protection Publication, UK.
18. Tyrkiel E. (1977) Mutagenic action of O-isopropoxyphenyl-N-methyl carbamate (propoxur) on mouse gametes. Roczniki Panstwowego Zakladu Higieny 28, 601-613.
19. Wattenberg L. W. and Loub W. D. (1978) Inhibition of polycyclic aromatic hydrocarbon induced neoplasia by naturally occurring indoles. Cancer Research 34, 1410-1413.
20. 450 mediated steroid hydroxylase activities in mice. Chemico-Biological Interactions 83, 155-169.
21. World Health Organization (1989) Pesticide Residues in Food. Evaluation Part II - Toxicology of Propoxur. pp. 183-214. WHO International Programme on Chemical Safety, Geneva.
22. Wortelboer H. M., Linden E. C. M., Kruif C. A., Noordhoek J. B., Laauboer B. J., Bladeren P. J. and Flake H. E. (1992) Effect of indole-3-carbinol on biotransformation enzymes in the rats: in vivo changes in liver and small intestine mucosa in comparison with primary hepatocyte culture. Food and Chemical Toxicology 30, 589-599.