Haplotype sharing analysis in affected individuals from nuclear families with at least one affected offspring

Genetic Epidemiology

Volumn 14, Issue 6, 1997, Pages 915-919

  Van Der Meulen, Martin A ^a   Te Meerman, Gerard J ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Haplotype sharing; Identity by descent; Linkage disequilibrium

Indexed keywords

CONFERENCE PAPER; FAMILY; GENE MAPPING; GENE MUTATION; GENETIC ANALYSIS; GENETIC LINKAGE; HAPLOTYPE; HUMAN; PROGENY;

CHROMOSOME MAPPING; FEMALE; GENETIC DISEASES, INBORN; GENOME, HUMAN; HAPLOTYPES; HUMANS; LOGISTIC MODELS; MALE; MUTATION; NUCLEAR FAMILY; PREDICTIVE VALUE OF TESTS;

EID: 0031441661     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(1997)14:6<915::AID-GEPI59>3.0.CO;2-P     Document Type: Conference Paper

References (5)

1. De Vries HG, Van der Meulen MA, Rozen R, Halley DJJ, Scheffer H, Ten Kate LP, Buys CHCM, Te Meerman GJ (1996): Haplotype identity between individuals who share a CFTR mutation allele identical by descent: demonstration of the usefulness of the haplotype sharing concept for gene mapping in real populations. Hum Genet 98:304-309.
2. Fisher RA (1930): "The Genetical Theory of Natural Selection." New York: Dover publications, 1st ed. (2nd rev ed 1958).
3. Houwen RHJ, Baharloo S, Blankenship K, Raeymaekers P, Juyn J, Sandkuijl LA, Freimer NB (1994): Genome screening by searching for shared segments: mapping a gene for benign recurrent intrahepatic cholestasis. Nat Genet 8:380-386.
4. Te Meerman GJ, Van der Meulen MA, Sandkuijl LA (1995): Perspectives of identity by descent (IBD) mapping in founder populations. Clin Exp Allergy 25:(suppl 2)97-102.
5. Van der Meulen MA, Te Meerman GJ (in press): Association and haplotype sharing due to identity by descent, with an application to genetic mapping. In: Edwards JH, Pawlowitzki IH, Thompson E (eds): "Genetic Mapping of Disease Genes." London: Academic Press Ltd.