Bronchial anti-spasmogenic effects and selectivity of T-440, phosphodiesterase type 4 inhibitor, in the dog

Biological and Pharmaceutical Bulletin

Volumn 20, Issue 12, 1997, Pages 1261-1265

  Yamagata, S ^a   Wada, K ^a   Sugaya, T ^a   Oka, K ^a   Kaminuma, O ^a   Kikkawa, H ^a   Ikezawa, K ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Bronchoconstriction; Cardiotonic effect; Phosphodiesterase inhibitor; Theophylline

Indexed keywords

4 [6,7 DIETHOXY 2,3 BIS(HYDROXYMETHYL) 1 NAPHTHYL] 1 (2 METHOXYETHYL) 2(1H) PYRIDINONE; 4,5 DIHYDRO 6 [4 (1H IMIDAZOL 1 YL)PHENYL] 5 METHYL 3(2H) PYRIDAZINONE; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM; THEOPHYLLINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHOSPASM; DOG; DOSE RESPONSE; DRUG ACTIVITY; DRUG POTENCY; DRUG SELECTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; FAST PROTEIN LIQUID CHROMATOGRAPHY; FEMALE; GUINEA PIG; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE PRESSURE; INTRAVENOUS DRUG ADMINISTRATION; LUNG; MALE; NONHUMAN; TRACHEA;

EID: 0031441406     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.20.1261     Document Type: Article

References (30)