Advances in the treatment of herpes simplex labialis

Antiviral Chemistry and Chemotherapy

Volumn 8, Issue SUPPL.1, 1997, Pages 69-73

  Spruance, S L ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

Aciclovir; Famciclovir; Herpes simplex labialis; Pain control; Penciclovir; Virus shedding

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; FAMCICLOVIR; IDOXURIDINE; PENCICLOVIR;

CLINICAL TRIAL; CONFERENCE PAPER; DISEASE COURSE; DRUG EFFICACY; DRUG INDICATION; HERPES LABIALIS; HERPES SIMPLEX VIRUS 1; HUMAN; ORAL DRUG ADMINISTRATION; PAIN; PRIORITY JOURNAL; TOPICAL DRUG ADMINISTRATION; VIRUS LATENCY; CONTROLLED CLINICAL TRIAL; CREAM; ERYTHEMA MULTIFORME; OINTMENT; RANDOMIZED CONTROLLED TRIAL; VIRUS SHEDDING;

DNA VIRUSES; HERPES;

EID: 0031439861     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (30)

1. Bratcher DF, Harrison CJ, Bourne N, Stanberry LR & Bernstein DI (1993) Effect of indomethacin on ultraviolet radiation-induced recurrent herpes simplex virus disease in guinea-pigs. Journal of General Virology 74: 1951-1954.
2. Corey L, Nahmias AJ, Guinan ME, Benedetti JK, Critchlow CW & Holmes KK (1982) A trial of topical acyclovir in genital herpes simplex virus infections. New England Journal of Medicine 2: 1313-1319.
3. Demangone M, Hill JM & Kwon BS (1987) Effects of acyclovir therapy during simultaneous reactivation of latent HSV-1 in rabbits. Antiviral Research 7: 237-243.
4. De Miranda P & Blum MR (1983) Pharmacokinetics of acyclovir after intravenous and oral administration. Journal of Antimicrobial Chemotherapy 12: 29-37.
5. Engler H, Zawatsky R, Kirchner H & Armerding D (1982) Experimental infection in inbred mice with herpes simplex virus. IV. Comparison of interferon production and natural killer cell activity in susceptible and resistant adult mice. Archives of Virology 74: 239-247.
6. Fiddian AP & Ivanyi L (1983) Topical acyclovir in the management of recurrent herpes labialis. British Journal of Dermatology 109: 321-326.
7. Freeman DJ, Sheth NV & Spruance SL (1986) Failure of topical acyclovir (ACV) in ointment to penetrate human skin. Antimicrobial Agents and Chemotherapy 29: 730-732.
8. Overall JC Jr (1984). Dermatologic viral diseases. In Antiviral Agents and Viral Diseases of Man, 2nd edition. Edited by Galasso GJ, Merigan TC & Buchanan RA New York; Raven Press, pp. 247-312.
9. Perkins SW & Sklarew EC (1996) Prevention of facial herpetic infections after chemical peel and dermabrasion: new treatment strategies in the prophylaxis of patients undergoing procedures of the perioral area. Plastic and Reconstructive Surgery 98: 427-433.
10. Raborn GW, McGaw WT, Grace M Tyrell LD, & Samuels S (1987) Oral acyclovir and herpes labialis: a randomized, double-blind, placebo-controlled study. Journal of the American Dentistry Association 115: 38-42.
11. Raborn GW, McGaw WT, Grace M & Houle L (1989a) Herpes labialis treatment with acyclovir 5 per cent ointment. Journal of the Canadian Dental Association 55: 135-137.
12. Raborn GW, McGaw WT, Grace M, Percy J & Samuels S (1989b) Herpes labialis treatment with acyclovir 5% modified aqueous cream: a double-blind, randomized trial. Oral Surgery, Oral Medicine, Oral Pathology 67: 676-679.
13. Rawls WE (1985). Herpes simplex virus. In Virology. Edited by Fields BN, Knipe DM, Chanock RM, Melnick JL, Roizman B & Shope RE. New York: Raven Press, pp. 527-61.
14. Romagnani S (1992) Induction of Th1 and Th2 responses: a key role for the "natural" immune response? Immunology Today 13: 379-381.
15. Rooney JF, Strauss SE, Mannix ML, Wohlenberg D, Alling JA, Dumois JA & Notkins AL (1993) Oral acyclovir to suppress frequently recurrent herpes labialis: a double-blind, placebo-controlled trial. Annals of Internal Medicine 118: 268-272.
16. Schmid DS & Rouse BT (1992) The role of T cell immunity in control of herpes simplex virus. Current Topics in Microbiology and Immunology 179: 57-74.
17. Shaw M, King M, Best JM, Banatvala JE, Gibson JR & Klaber MR (1985) Failure of acyclovir cream in treatment of recurrent herpes labialis. British Medical Journal 291: 7-9.
18. Spruance SL, Overall JC Jr, Kern ER, Krueger GG, Pliam V & Miller W (1977) The natural history of recurrent herpes simplex labialis. Implications of antiviral therapy. New England Journal of Medicine 297: 69-75.
19. Spruance SL, Schnipper LE, Overall JC Jr, Kern B, Wester J, Modlin G, Wenerstrom C, Burton C, Arndt KA & Crumpacker CS (1982) Treatment of herpes simplex labialis with topical acyclovir in polyethylene glycol. Journal of Infectious Diseases 146: 85-90.
20. Spruance SL, Crumpacker CS, Schnipper LE, Kern B, Marlow KA, Arndt KA & Overall JC Jr (1984a) Early, patient-initiated treatment of herpes labialis with topical 10% acyclovir. Antimicrobial Agents and Chemotherapy 25: 553-555.
21. Spruance SL &. Wenerstrom G (1984b) Pathogenesis of herpes simplex labialis: IV. Maturation of lesions within 8 hours after onset and implications for antiviral treatment. Oral Surgery, Oral Medicine, Oral Pathology 58: 667-671.
22. Spruance SL, Hammil ML, Hoge WS, Davis G & Mills J. (1988) Acyclovir prevents reactivation of herpes labialis in skiers. Journal of the American Medical Association 260: 1597-1599.
23. Spruance SL, Stewart JCB, Freeman DJ, Brightman VJ, Cox JL, Wenerstrom G, McKeough MB & Rowe NH (1990a) Early application of topical 15% idoxuridine in dimethyl sulfoxide shortens the course of herpes simplex labialis: a multicenter placebo-controlled trial. Journal of Infectious Diseases 161: 191-197.
24. Spruance SL, Stewart JCB, Rowe NH, McKeough MB, Wenerstrom G & Freeman DJ (1990b) Treatment of recurrent herpes simplex labialis with oral acyclovir. Journal of Infectious Diseases 161: 185-190.
25. Spruance SL (1993) Prophylactic chemotherapy with acyclovir for recurrent herpes simplex labialis. Journal of Medical Virology 41(Supplement 1): 27-32.
26. Spruance SL, Rea TL, Thoming C, Tucker R, Saltzman R & Boon R (1997) Penciclovir cream for the treatment of herpes simplex labialis: a randomized, multicenter, double-blind, placebo-controlled trial. Journal of the American Medical Association 277: 1374-1379.
27. Straus SE, Smith HA, Brickman C, deMiranada P, McLaren C & Keeney RE (1982) Acyclovir for chronic mucocutaneous herpes simplex virus infection in immunosuppressed patients. Annals of Internal Medicine 96: 270-277.
28. Van Vloten WA, Swart RNJ & Pot F (1983) Topical acyclovir therapy in patients with recurrent orofacial herpes simplex infections. Journal of Antimicrobial Chemotherapy 12: 89-93.
29. Wade JC, Newton B, McLaren C, Flournoy N, Keeney RE & Meyers JD (1982) Intravenous acyclovir to treat mucocutaneous herpes simplex virus infection after marrow transplantation. Annals of Internal Medicine 96: 265-269.
30. Whitley RJ, Levin M, Barton N, Hershey BJ, Davis G, Keeney RE, Whelchel J, Diethelm AG, Kartus P & Soong SJ (1984) Infections caused by herpes simplex virus in the immunocompromised host: natural history and topical acyclovir therapy. Journal of Infectious Diseases 150: 323-329.