Both the cyclic AMP response element and the activator protein 2 binding site mediate basal and cyclic AMP-induced transcription from the dominant promoter of the rat α(1B)-adrenergic receptor gene in DDT1MF-2 cells

Molecular Pharmacology

Volumn 52, Issue 6, 1997, Pages 1019-1026

  Gao, Bin ^a,b   Chen, Jianping ^a   Johnson, Carl ^a   Kunos, George ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; CYCLIC AMP;

ANIMAL CELL; ARTICLE; BINDING SITE; DRUG RECEPTOR BINDING; GENE MUTATION; GENETIC TRANSCRIPTION; GLYCOGENOLYSIS; HAMSTER; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN SYNTHESIS INHIBITION; RECEPTOR GENE; THYROID CELL; TISSUE SPECIFICITY;

EID: 0031439584     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.52.6.1019     Document Type: Article

References (40)

1. 1-Adrenergic receptor subtypes: molecular structure, function, and signaling. Circ. Res. 78: 737-749 (1996).
2. 1-Adrenergic receptor subtypes. Annu. Rev. Pharmacol. Toxicol. 34: 117-133 (1994).
3. 1-Adrenergic receptor subtypes, inositol phosphates and sources of cell calcium. Pharmacol. Rev. 40:87-119 (1988).
4. 2-adrenergic receptors. Ann. N. Y. Acad. Sci. 757: 261-270 (1995).
5. 1B adrenergic receptor. Gene 131: 243-247 (1993).
6. 1BAR gene in rat liver is controlled by three promoters. J. Biol. Chem. 269: 15762-15767 (1994).
7. 1B adrenergic receptor gene middle promoter contains multiple binding sites for sequence-specific proteins including a novel ubiquitous transcription factor. J. Biol. Chem. 270: 5614-5619 (1995).
8. 1BAR gene expression in regenerating liver. Mol. Cell. Biol. 16: 5997-6008 (1996).
9. 1 adrenergic receptor gene transcripts in the rat. Mol. Cell. Endocrinol. 74: 1-9 (1990).
10. 1A adrenergic receptor. J. Biol. Chem. 266: 6365-6369 (1991).
11. 1B-adrenergic receptor activation in rat medullary thyroid carcinoma 6-23 cells. Mol. Pharmacol. 45: 591-598 (1994).
12. 1MF-2 cells. J. Biol. Chem. 268 3610-3615 (1993).
13. 1B adrenergic receptor by thyrotropin. J. Clin. Invest. 94: 2245-2254 (1994).
14. 1B-linked response via an adenosine 3′, 5'′-monophosphate protein kinase-A-dependent pathway. Endocrinology 134: 424-431 (1994).
15. Morris, G. M., J. R. Hadcock, and C. C. Malbon. Cross regulation between G-protein coupled receptors. J. Biol. Chem. 266: 2233-2238 (1991).
16. 1-adrenergic receptors in cultured thyroid cells. J. Biol. Chem. 260:9230-9236 (1985).
17. 1B-adrenergic receptor mRNA: day/night rhythm and β-adrenergic receptor/cyclic AMP control. Mol. Pharmacol. 51:551-557 (1997).
18. Roesler, W. J., G. R. Vandenbark, and R. W. Cyclic AMP and the induction of eukaryotic gene transcription. J. Biol. Chem. 263: 9063-9066 (1988).
19. 2 adrenergic receptor gene in rat liver: the negative regulatory role of C/EBPα. Biochemistry 35: 13136-13146 (1996).
20. Grieco, D., A. Porcellini, E. V. Avvedimento, and M. E. Gotsman. Requirement for cAMP-PKA pathway activation by M phase promoting factor in the transition from mitosis to interphase. Science (Washington D. C.) 271:1718-1723 (1996).
21. 1MF-2 smooth muscle cells. Mol. Pharmacol. 44:1105-1112 (1993).
22. 2A adrenergic receptor gene in HT-29 cells. J. Biol. Chem. 266:5743-5749 (1991).
23. 1B adrenergic receptor. J. Biol. Chem. 267: 21936-21945 (1992).
24. Fink, J. S., M. Verhave, K. Walton, G. Mandel, and R. H. Goodman. Cyclic AMP-and phorbol ester-induced transcriptional activation are mediated by the same enhancer element in the human vasoactive intestinal peptide gene. J. Biol. Chem. 266: 3882-3887 (1991).
25. Suwanichkul, A., L. A. DePaolis, P. K. Lee, and D. R. Powell. Identification of a promoter element which participates in cAMP-stimulatcd expression of human insulin-like growth factor binding protein-1. J. Biol. Chem. 268: 9730-9736 (1993).
26. Comb, M., N. C. Birnberg, A. Seasholtz, E. Herbert, and H. Goodman. A cyclic AMP and phorbol ester-inducible DNA element. Nature (Lond.) 323: 353-356 (1986).
27. Hozawa, S. E. J. Holtzman, and D. A. Ausiello. cAMP motifs regulating transcription in the aquaporin 2 gene. Am. J. Physiol. 270:C1695-C1702 (1996).
28. Hoeffler, J. P., T. E. Meyer, Y. Yun, J. L. Jameson, and J. F. Habener. Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA. Science (Washington D. C.) 242: 1430-1433 (1988).
29. Gonzalez, G. A., and M. R. Montminy. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59: 675-680 (1989).
30. Alberts, A. S., J. Arias, M. Hagiwara, M. R. Montminy, and J. R. Feramisco Recombinant cyclic AMP response element binding protein (CREB) phosphorylated on ser-133 is transcriptionally active upon its introduction into fibroblast nuclei. J. Biol. Chem. 269: 7623-7630 (1994).
31. Gonzalez, G. A., K. K. Yamamoto, W. H. Fischer, D. Karr, P. Menzel, W. Biggs, W. Vale, and M. R. Montminy. A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence. Nature (Lond.) 337: 749-752 (1989).
32. Yamamoto, K. K., G. A. Gonzalez, W. Biggs, W. W. Vale, and M. R. Montminy. Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. Nature (Lond.) 334: 494-498 (1988).
33. Rehfuss, R. P., K. M. Walton, M. M. Loriaux, and R. H. Goodman. The cAMP-regulated enhancer binding protein ATF-1 activates transcription in response to cAMP dependent protein kinase A. J. Biol. Chem. 266: 18431-18434 (1991).
34. Liu, F., M. A. Thompson, S. Wagner, M. E. Greenberg, and M. R. Green. Activating transcription factor-1 can mediate Ca(2+)-and cAMP-inducible transcriptional activation. J. Biol. Chem. 268: 6714-6720 (1993).
35. Quinn, P. G. Distinct activation domains within cAMP response element binding protein mediate basal and cAMP-stimulated transcription. J. Biol. Chem. 268: 16999-17009 (1993).
36. Delegeane, A. M., L. H. Ferland, and P. L. Mellon. Tissue-specific enhancer of human glycoprotein hormone α-subunit gene: dependence on cyclic AMP-inducible elements. Mol. Cell. Biol. 7: 3994-4002 (1987).
37. Mitchell, P. J., C. Wang, and R. Tjian. Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen. Cell 50: 847-861 (1987).
38. Imagawa, M., R. Chiu, and M. Karin. Transcription factor AP2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP. Cell 51: 251-260 (1987).
39. 1B adrenergic receptor gene. FASEB J. 9:A105 (1995).
40. 1B-adrenergic receptor gene promotor region and hypoxia regulatory elements in vascular smooth muscle. Proc. Natl. Acad. Sci. USA. 94: 9487-9492 (1997).