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Drug Metabolism and Drug Interactions
Volumn 14, Issue 2, 1997, Pages 83-98
Microsomal metabolism of N-benzyl-N-ethylaniline and N-benzyl-N-ethyl-p-toluidine
Author keywords

Dealkylation; Debenzylation; In vitro metabolism; Tertiary benzylic amines
Indexed keywords

ANILINE DERIVATIVE; N BENZYL N ETHYL 4 TOLUIDINE; N BENZYL N ETHYLANILINE; UNCLASSIFIED DRUG;
EID: 0031438776     PISSN: 07925077     EISSN: None     Source Type: Journal    
DOI: 10.1515/DMDI.1997.14.2.83     Document Type: Short Survey
Times cited : (5)
References (11)
  • 1
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    • Gorrod JW, Damani LA, eds, Chichester: Ellis Horwood
    • Gooderham NJ, Gorrod JW. Microsomal N-oxidation of secondary aromatic amines.In: Gorrod JW, Damani LA, eds, Biological Oxidation of Nitrogen in Organic Molecules. Chichester: Ellis Horwood, 1985; 81-95.
    • (1985) Biological Oxidation of Nitrogen in Organic Molecules , pp. 81-95
    • Gooderham, N.J.1    Gorrod, J.W.2
  • 2
    • 0022402105 scopus 로고
    • Microsomal N- and C-oxidation of 4-substituted N-benzylanilines
    • Gorrod JW, Gooderham NJ. Microsomal N- and C-oxidation of 4-substituted N-benzylanilines. Xenobiotica 1985; 15: 1021-1031.
    • (1985) Xenobiotica , vol.15 , pp. 1021-1031
    • Gorrod, J.W.1    Gooderham, N.J.2
  • 3
    • 0345064474 scopus 로고
    • Microsomal formation of amides from secondary aromatic amines
    • Gorrod JW, Gibson GG, Mitchard M, eds, Chichester: Ellis Horwood
    • Gooderham NJ, Gorrod JW. Microsomal formation of amides from secondary aromatic amines. In: Gorrod JW, Gibson GG, Mitchard M, eds, Development of Drugs and Modern Medicines. Chichester: Ellis Horwood, 1986; 318-323.
    • (1986) Development of Drugs and Modern Medicines , pp. 318-323
    • Gooderham, N.J.1    Gorrod, J.W.2
  • 5
    • 0027963608 scopus 로고
    • Structure-activity relationships in the formation of amides from substituted N-benzylanilines
    • Ulgen M, Gorrod JW, Barlow D. Structure-activity relationships in the formation of amides from substituted N-benzylanilines. Xenobiotica 1994; 24: 735-748.
    • (1994) Xenobiotica , vol.24 , pp. 735-748
    • Ulgen, M.1    Gorrod, J.W.2    Barlow, D.3
  • 6
    • 0003812565 scopus 로고
    • Amsterdam: Elsevier Publishing Company
    • Ochiai E. Aromatic Amine Oxides. Amsterdam: Elsevier Publishing Company, 1967.
    • (1967) Aromatic Amine Oxides
    • Ochiai, E.1
  • 7
    • 0026779931 scopus 로고
    • Microsomal formation of N-benzyl-4-hydroxymethylaniline from N-benzyl-4-methylaniline
    • Ulgen M, Gorrod JW. Microsomal formation of N-benzyl-4-hydroxymethylaniline from N-benzyl-4-methylaniline. J Pharm Pharmacol 1992; 44: 865-866.
    • (1992) J Pharm Pharmacol , vol.44 , pp. 865-866
    • Ulgen, M.1    Gorrod, J.W.2
  • 8
    • 0017833014 scopus 로고
    • Preparation of microsomes with calcium
    • Schenkman JB, Cinti DL. Preparation of microsomes with calcium. Meth Enzymol 1978; 52: 83-89.
    • (1978) Meth Enzymol , vol.52 , pp. 83-89
    • Schenkman, J.B.1    Cinti, D.L.2
  • 9
    • 0027968749 scopus 로고
    • Metabolic and chemical studies on αN-diarylnitrones
    • Ulgen M, Gorrod JW. Metabolic and chemical studies on αN-diarylnitrones. Drug Metab Drug Interact 1994; 11: 245-257.
    • (1994) Drug Metab Drug Interact , vol.11 , pp. 245-257
    • Ulgen, M.1    Gorrod, J.W.2
  • 10
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    • Hydroxylation of alkyl and halogen substituted anilines and acetanilides by microsomal hydroxylases
    • Daly JW, Guroff G, Udenfriend S, Witkop B. Hydroxylation of alkyl and halogen substituted anilines and acetanilides by microsomal hydroxylases. Biochem Pharmacol 1967; 17: 31-36.
    • (1967) Biochem Pharmacol , vol.17 , pp. 31-36
    • Daly, J.W.1    Guroff, G.2    Udenfriend, S.3    Witkop, B.4
  • 11
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    • Evidence for p-hydroxylation of N-ethyl-N-methylaniline
    • Gorrod JW, Patterson LH. Evidence for p-hydroxylation of N-ethyl-N-methylaniline. Xenobiotica 1980; 10: 603-610.
    • (1980) Xenobiotica , vol.10 , pp. 603-610
    • Gorrod, J.W.1    Patterson, L.H.2

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.