메뉴 건너뛰기




Volumn 90, Issue 1, 1997, Pages 247-267

Molecular cloning, characterization and overexpression of two distinct cysteine protease cDNAs from Leishmania donovani chagasi

Author keywords

Amastigote specific; cDNA; Cysteine proteases; Leishmania donovani chagasi; Overexpression; Promastigote specific

Indexed keywords

COMPLEMENTARY DNA; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR;

EID: 0031437260     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(97)00158-8     Document Type: Article
Times cited : (35)

References (46)
  • 1
    • 33947408476 scopus 로고
    • WHO Technical Report Series 793
    • WHO Technical Report Series 793. Control of Leishmaniasis. 1990.
    • (1990) Control of Leishmaniasis
  • 2
    • 0027428152 scopus 로고
    • The proteases and the pathogenicity of parasitic protozoa
    • McKerrow J.H. The proteases and the pathogenicity of parasitic protozoa. Ann Rev Microbiol. 47:1993;821-853.
    • (1993) Ann Rev Microbiol , vol.47 , pp. 821-853
    • McKerrow, J.H.1
  • 3
    • 0021344272 scopus 로고
    • Inhibition of Leishmania amastigote growth by antipain and leupeptin
    • Combs G.H., Baxter J. Inhibition of Leishmania amastigote growth by antipain and leupeptin. Ann Trop Med Parasitol. 78:1984;21-24.
    • (1984) Ann Trop Med Parasitol , vol.78 , pp. 21-24
    • Combs, G.H.1    Baxter, J.2
  • 5
    • 0028202206 scopus 로고
    • Multiple high activity cysteine proteases of Leishmania mexicana are encoded by the lmcpb gene array
    • Robertson C.L., Coombs G.H. Multiple high activity cysteine proteases of Leishmania mexicana are encoded by the lmcpb gene array. Microbiology. 140:1994;417-424.
    • (1994) Microbiology , vol.140 , pp. 417-424
    • Robertson, C.L.1    Coombs, G.H.2
  • 7
    • 0029898541 scopus 로고    scopus 로고
    • Evidence from disruption of lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors
    • Mottram J.C., Souza E.A., Hutchinson J.E., Carter R., Frame M.J., Coombs G.H. Evidence from disruption of lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors. Proc Natl Acad Sci USA. 93:1996;6008-6013.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6008-6013
    • Mottram, J.C.1    Souza, E.A.2    Hutchinson, J.E.3    Carter, R.4    Frame, M.J.5    Coombs, G.H.6
  • 8
    • 0016376184 scopus 로고
    • Comparative specificity of microbial proteinases
    • Morihara K. Comparative specificity of microbial proteinases. Adv Enzymol. 41:1974;179-243.
    • (1974) Adv Enzymol , vol.41 , pp. 179-243
    • Morihara, K.1
  • 9
    • 0000686943 scopus 로고
    • Viral cysteine proteinases are homologous to the trypsin-like family of serine proteases: Structural and functional implications
    • Bazan J.F., Fletterick J.R. Viral cysteine proteinases are homologous to the trypsin-like family of serine proteases: Structural and functional implications. Proc Natl Acad Sci USA. 85:1988;7872-7876.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7872-7876
    • Bazan, J.F.1    Fletterick, J.R.2
  • 10
    • 0024467833 scopus 로고
    • Regulation of Trichophyton rubrum proteolytic activity
    • Apodaca G., McKerrow J.H. Regulation of Trichophyton rubrum proteolytic activity. Infect Immun. 57:1989;3081-3090.
    • (1989) Infect Immun , vol.57 , pp. 3081-3090
    • Apodaca, G.1    McKerrow, J.H.2
  • 11
    • 0025176948 scopus 로고
    • Amplification and sequencing of genomic DNA fragments encoding cysteine proteases from protozoan parasite
    • Eakin A.E., Bouvier J., Sakanari J.A., Craik C.S., McKerrow J.H. Amplification and sequencing of genomic DNA fragments encoding cysteine proteases from protozoan parasite. Mol Biochem Parasitol. 39:1990;1-8.
    • (1990) Mol Biochem Parasitol , vol.39 , pp. 1-8
    • Eakin, A.E.1    Bouvier, J.2    Sakanari, J.A.3    Craik, C.S.4    McKerrow, J.H.5
  • 12
    • 0019617865 scopus 로고
    • Proteinases of Leishmania mexicana amastigotes and promastigotes: Analysis by gel electrophoresis
    • North M.J., Coombs G.H. Proteinases of Leishmania mexicana amastigotes and promastigotes: Analysis by gel electrophoresis. Mol Biochem Parasitol. 3:1981;293-300.
    • (1981) Mol Biochem Parasitol , vol.3 , pp. 293-300
    • North, M.J.1    Coombs, G.H.2
  • 13
    • 0020004009 scopus 로고
    • Proteinases of Leishmania and other flagellate protozoan
    • Coombs G.H. Proteinases of Leishmania and other flagellate protozoan. Parasitology. 84:1982;149-155.
    • (1982) Parasitology , vol.84 , pp. 149-155
    • Coombs, G.H.1
  • 14
    • 0021137779 scopus 로고
    • Purification and characterization of proteolytic enzymes of Leishmania amastigotes and promastigotes
    • Pupkis M.F., Combs G.H. Purification and characterization of proteolytic enzymes of Leishmania amastigotes and promastigotes. J Gen Microbiol. 130:1984;2375-2383.
    • (1984) J Gen Microbiol , vol.130 , pp. 2375-2383
    • Pupkis, M.F.1    Combs, G.H.2
  • 15
    • 0022479593 scopus 로고
    • Leishmania mexicana: Amastigote hydrolases in unusual lysosomes
    • Pupkis M.F., Tetley F., Coombs G.H. Leishmania mexicana: amastigote hydrolases in unusual lysosomes. Exp Parasitol. 62:1986;29-39.
    • (1986) Exp Parasitol , vol.62 , pp. 29-39
    • Pupkis, M.F.1    Tetley, F.2    Coombs, G.H.3
  • 16
    • 0026708826 scopus 로고
    • A developmentally regulated cysteine proteinase gene of Leishmania mexicana
    • Mottram J.C., Robertson C.D., Coombs G.H., Barry J.D. A developmentally regulated cysteine proteinase gene of Leishmania mexicana. Mol Microbiol. 6:1992;1925-1932.
    • (1992) Mol Microbiol , vol.6 , pp. 1925-1932
    • Mottram, J.C.1    Robertson, C.D.2    Coombs, G.H.3    Barry, J.D.4
  • 17
    • 0026783342 scopus 로고
    • Characterization of a multi-copy gene for a major stage-specific cysteine proteinase of Leishmania mexicana
    • Souza A.E., Waugh S., Coombs G.H., Mottram J.C. Characterization of a multi-copy gene for a major stage-specific cysteine proteinase of Leishmania mexicana. FEBS Lett. 311:1992;124-127.
    • (1992) FEBS Lett , vol.311 , pp. 124-127
    • Souza, A.E.1    Waugh, S.2    Coombs, G.H.3    Mottram, J.C.4
  • 18
    • 0027476019 scopus 로고
    • Identification of two distinct cysteine proteinase genes of Leishmania pifanoi axenic amastigotes using polymerase chain reaction
    • Traub-Cseko Y.M., Duboise M., Boukai L.K., McMahon-Pratt M. Identification of two distinct cysteine proteinase genes of Leishmania pifanoi axenic amastigotes using polymerase chain reaction. Mol Biochem Parasitol. 57:1993;101-116.
    • (1993) Mol Biochem Parasitol , vol.57 , pp. 101-116
    • Traub-Cseko, Y.M.1    Duboise, M.2    Boukai, L.K.3    McMahon-Pratt, M.4
  • 19
    • 0024575730 scopus 로고
    • Identification of developmentally regulated cysteine protease of Trypanosoma cruzi
    • Pamer E.G., So M., Davis C.E. Identification of developmentally regulated cysteine protease of Trypanosoma cruzi. Mol Biochem Parasitol. 33:1989;27-32.
    • (1989) Mol Biochem Parasitol , vol.33 , pp. 27-32
    • Pamer, E.G.1    So, M.2    Davis, C.E.3
  • 20
    • 0025707153 scopus 로고
    • A major cysteine proteinase is developmentally regulated in Trypanosoma cruzi
    • Campetella O., Martinez J., Cazzullo J.J. A major cysteine proteinase is developmentally regulated in Trypanosoma cruzi. FEMS Microbiol Lett. 67:1990;145-150.
    • (1990) FEMS Microbiol Lett , vol.67 , pp. 145-150
    • Campetella, O.1    Martinez, J.2    Cazzullo, J.J.3
  • 21
    • 0023566939 scopus 로고
    • Analysis of Leishmania proteinases reveals developmentally changes in species-specific forms and a common 68-kDa activity
    • Lockwood B.C., North M.J., Mallinson D.J., Coombs G.H. Analysis of Leishmania proteinases reveals developmentally changes in species-specific forms and a common 68-kDa activity. FEMS Microbiol Lett. 48:1987;345-350.
    • (1987) FEMS Microbiol Lett , vol.48 , pp. 345-350
    • Lockwood, B.C.1    North, M.J.2    Mallinson, D.J.3    Coombs, G.H.4
  • 22
    • 0018974603 scopus 로고
    • Mechanism of lethal effect of human serum upon Leishmania donovani
    • Pearson R.D., Steigbigel R.T. Mechanism of lethal effect of human serum upon Leishmania donovani. J Immunol. 125:1980;2195-2201.
    • (1980) J Immunol , vol.125 , pp. 2195-2201
    • Pearson, R.D.1    Steigbigel, R.T.2
  • 26
    • 0026832163 scopus 로고
    • A physical map of Salmonella typhimurium LT2 genome made by using XbaI analysis
    • Liu S.-L., Sanderson K.E. A physical map of Salmonella typhimurium LT2 genome made by using XbaI analysis. J Bacteriol. 174:1992;1662-1672.
    • (1992) J Bacteriol , vol.174 , pp. 1662-1672
    • Liu, S.-L.1    Sanderson, K.E.2
  • 27
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
    • Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:1987;156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 30
    • 0027351065 scopus 로고
    • Transfection of Leishmania and Trypanosoma brucei by electroporation
    • Beverley S.M., Clayton C.E. Transfection of Leishmania and Trypanosoma brucei by electroporation. Methods Mol Biol. 21:1993;333-348.
    • (1993) Methods Mol Biol , vol.21 , pp. 333-348
    • Beverley, S.M.1    Clayton, C.E.2
  • 31
    • 0026511191 scopus 로고
    • Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larvae migrans
    • Hotez P.J., Narasimhan S., Haggerty J., Milstone L., Bhopale V., Schad G.A., Richards F.F. Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larvae migrans. Infect Immun. 160:1992;1018-1023.
    • (1992) Infect Immun , vol.160 , pp. 1018-1023
    • Hotez, P.J.1    Narasimhan, S.2    Haggerty, J.3    Milstone, L.4    Bhopale, V.5    Schad, G.A.6    Richards, F.F.7
  • 33
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 35
  • 36
    • 0027537709 scopus 로고
    • The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi
    • Eakin E.E., Mills A.A., Harth G., McKerrow J.H., Craik C.S. The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi. J Biol Chem. 268:1992;6115-6118.
    • (1992) J Biol Chem , vol.268 , pp. 6115-6118
    • Eakin, E.E.1    Mills, A.A.2    Harth, G.3    McKerrow, J.H.4    Craik, C.S.5
  • 37
    • 0024329436 scopus 로고
    • A cysteine proteinase cDNA from Trypanosoma brucei predicts an enzyme with an unusual c-terminus extension
    • Mottram J.C., North M.J., Barry J.D., Coombs G.H. A cysteine proteinase cDNA from Trypanosoma brucei predicts an enzyme with an unusual c-terminus extension. FEBS Lett. 258:1989;211-215.
    • (1989) FEBS Lett , vol.258 , pp. 211-215
    • Mottram, J.C.1    North, M.J.2    Barry, J.D.3    Coombs, G.H.4
  • 38
    • 0026570815 scopus 로고
    • The major cysteine proteinase (cruzipain) from Trypanosoma cruzi is encoded by multiple polymorphic tandemly organized genes located on different chromosomes
    • Campetella O., Henriksson J., Asund L., Frasch A.C.C., Petersson U., Cazzullo J.J. The major cysteine proteinase (cruzipain) from Trypanosoma cruzi is encoded by multiple polymorphic tandemly organized genes located on different chromosomes. Mol Biochem Parasitol. 50:1992;225-234.
    • (1992) Mol Biochem Parasitol , vol.50 , pp. 225-234
    • Campetella, O.1    Henriksson, J.2    Asund, L.3    Frasch, A.C.C.4    Petersson, U.5    Cazzullo, J.J.6
  • 39
    • 0028959215 scopus 로고
    • Nucleic acids: Vaccines of the future
    • Waine G.J., McManus D.P. Nucleic acids: vaccines of the future. Parasitol Today. 11:1995;113-116.
    • (1995) Parasitol Today , vol.11 , pp. 113-116
    • Waine, G.J.1    McManus, D.P.2
  • 41
    • 0001221937 scopus 로고    scopus 로고
    • DNA vaccines promising: A new approach to inducing protective immunity
    • Ulmer J.B., Donnelly J.J., Liu M.A. DNA vaccines promising: A new approach to inducing protective immunity. Am Soc Microbiol News. 62(9):1996;476-479.
    • (1996) Am Soc Microbiol News , vol.62 , Issue.9 , pp. 476-479
    • Ulmer, J.B.1    Donnelly, J.J.2    Liu, M.A.3
  • 42
    • 0026085421 scopus 로고
    • Transient activity assays of the Trypanosoma brucei variant surface glycoprotein gene promoter: Control of gene expression at the post-transcriptional level
    • Jefferies D., Tebabi P., Pays E. Transient activity assays of the Trypanosoma brucei variant surface glycoprotein gene promoter: control of gene expression at the post-transcriptional level. Mol Cell Biol. 11:1991;338-343.
    • (1991) Mol Cell Biol , vol.11 , pp. 338-343
    • Jefferies, D.1    Tebabi, P.2    Pays, E.3
  • 43
    • 0026598731 scopus 로고
    • Three distinct RNAs for the surface protease gp63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form
    • Ramamoorthy R., Donelson J.E., Paetz K.E., Maybodi M., Roberts S.C., Wilson M.E. Three distinct RNAs for the surface protease gp63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form. J Biol Chem. 267:1992;1888-1895.
    • (1992) J Biol Chem , vol.267 , pp. 1888-1895
    • Ramamoorthy, R.1    Donelson, J.E.2    Paetz, K.E.3    Maybodi, M.4    Roberts, S.C.5    Wilson, M.E.6
  • 44
    • 0029087808 scopus 로고
    • Post-transcriptional elements regulating expression of mRNAs from the amastin/tuzin gene cluster of Trypanosoma cruzi
    • Teixeira S.M., Kirchhoff L., Danelson J. Post-transcriptional elements regulating expression of mRNAs from the amastin/tuzin gene cluster of Trypanosoma cruzi. J Biol Chem. 270:1995;22586-22594.
    • (1995) J Biol Chem , vol.270 , pp. 22586-22594
    • Teixeira, S.M.1    Kirchhoff, L.2    Danelson, J.3
  • 45
    • 0030035450 scopus 로고    scopus 로고
    • The developmental expression of Leishmania donovani A2 amastigote-specific genes is post-transcriptionally mediated and involves elements located in the 3′-untranslated region
    • Charest H., Zhang W.-W., Matlashewski G. The developmental expression of Leishmania donovani A2 amastigote-specific genes is post-transcriptionally mediated and involves elements located in the 3′-untranslated region. J Biol Chem. 271:1996;17081-17090.
    • (1996) J Biol Chem , vol.271 , pp. 17081-17090
    • Charest, H.1    Zhang, W.-W.2    Matlashewski, G.3
  • 46
    • 0027947483 scopus 로고
    • Distribution of parasite cysteine proteases in lesions of mice infected with Leishmania mexicana amastigotes
    • Ilg T., Fuchs M., Gnau V., Wolfram M., Harbecke D., Overath P. Distribution of parasite cysteine proteases in lesions of mice infected with Leishmania mexicana amastigotes. Mol Biochem Parasitol. 67:1994;193-203.
    • (1994) Mol Biochem Parasitol , vol.67 , pp. 193-203
    • Ilg, T.1    Fuchs, M.2    Gnau, V.3    Wolfram, M.4    Harbecke, D.5    Overath, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.