Tumor angiogenesis as a prognostic factor in ovarian carcinoma: Quantification of endothelial immunoreactivity by image analysis

Cancer

Volumn 80, Issue 12, 1997, Pages 2257-2262

  Schoell, Wolfgang M J ^a   Pieber, Doris ^a   Reich, Olaf ^a   Lahousen, Manfred ^a   Janicek, Mike ^b   Guecer, Fatih ^c   Winter, Raimund ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b UNIVERSITY OF MIAMI   (United States)

^c University of Graz ^*

Author keywords

Angiogenesis; Image analysis; Ovarian carcinoma; Prognosis

Indexed keywords

ADULT; AGED; ANGIOGENESIS; ARTICLE; CLINICAL ARTICLE; COMPUTER ASSISTED DIAGNOSIS; CONTROLLED STUDY; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; OVARY CARCINOMA; PRIORITY JOURNAL; PROGNOSIS; QUANTITATIVE DIAGNOSIS; TUMOR VASCULARIZATION;

ANTIGENS, CD31; ANTIGENS, CD34; CAPILLARIES; DISEASE PROGRESSION; ENDOTHELIUM, VASCULAR; FACTOR VIII; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOENZYME TECHNIQUES; NEOPLASM STAGING; NEOVASCULARIZATION, PATHOLOGIC; OVARIAN NEOPLASMS; PROGNOSIS; SURVIVAL RATE;

EID: 0031437089     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19971215)80:12<2257::AID-CNCR6>3.0.CO;2-R     Document Type: Article

References (26)

1. Folkman J, Watson K, Ingber D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 1989;339:58-61.
2. Gasparini G, Weidner N, Bevilacqua P, Maluta S, Palma PD, Caffo O, et al. Tumor microvessel density, p53 expression, tumor size, and peritumoral lymphatic vessel invasion are relevant prognostic markers in node-negative breast carcinoma. J Clin Oncol 1994;12:454-66.
3. Weidner N, Semple IP, Welch WR, Folkman J. Tumor angiogenesis and metastasis correlation in invasive breast carcinoma. N Engl J Med 1991;324:1-8.
4. Weidner N, Folkman J, Pozza F, Bevilacqua P, Allred EN, Moore DH, et al. Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 1992;84:1875-87.
5. Bosari S, Lee AKC, Delellis RA, Wiley BD, Heatley GJ, Silverman ML. Microvessel quantitation and prognosis in invasive breast carcinoma. Hum Pathol 1992;23:755-61.
6. Horak ER, Leek R, Klenk N, Lejune S, Smith K, Stuart N, et al. Angiogenesis assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer. Lancet 1992;340:1120-4.
7. Obermair A, Kurz C, Czerwenka K, Thoma M, Kaider A, Wagner T, et al. Microvessel density and vessel invasion in lymph-node-negative breast cancer: effect on recurrence-free survival. Int J Cancer 1995;62:126-31.
8. Yanase T, Tamura M, Fujita K, Kodama S, Tanaka K. Inhibitory effect of angiogenesis inhibitor TNP-470 on tumor growth and metastasis of human cell lines in vitro and in vivo Cancer Res 1993;53:2566-70.
9. Ingber D, Fujita T, Kishimoto S, Sudo K, Kanamaru T, Brem H, et al. Synthetic analogues of fumagilin that inhibit angiogenesis and suppress tumor growth. Nature 1990;348:555-7.
10. Fox SB, Turner GDH, Leek RD, Whitehouse RM, Gatter KC, Harris AL. The prognostic value of quantitative angiogenesis in breast cancer and role of adhesion molecule expression in tumor endothelium. Breast Cancer Res Treat 1995;36:219-26.
11. Takebayashi Y, Akiyama S, Yamada K, Akiba S, Aikou T. Angiogenesis as an unfavorable prognostic factor in human colorectal carcinoma. Cancer 1996;78:226-31.
12. Morgan KG, Wilkinson N, Buckley CH. Angiogenesis in endometrial carcinoma. Int J Gynecol Cancer 1996;6:385-8.
13. Brawer MK. Quantitative microvessel density. A staging and prognostic marker for human prostatic carcinoma. Cancer 1996;78:345-9.
14. Page DL, Jensen RA. Angiogenesis in human breast carcinoma: what is the question? Hum Pathol 1995;26:1173-4.
15. Costello P, McCann A, Carney DN, Dervan PA. Prognostic significance of microvessel density in lymph node negative breast carcinoma. Hum Pathol 1995;26:1181-4.
16. Goulding H, Rashid NA, Robertson JF, Bell JA, Elston CW, Blarney RW, et al. Assessment of angiogenesis in breast carcinoma: an important factor in prognosis? Hum Pathol 1995;26:1196-200.
17. Miliaras D, Kamas A, Kalekou H. Angiogenesis in invasive breast carcinoma: is it associated with parameters of prognostic significance? Histopathology 1995;26:165-9.
18. Kirschner CV, Alanis-Amezcua JM, Martin VG, Luna N, Morgan E, Yang JJ, et al. Angiogenesis factor in endometrial carcinoma: a new prognostic indicator? Am J Obstet Gynecol 1996;174:1879-84.
19. Dinh TV, Hannigan EV, Smith ER, Hove MJ, Chopra V, To T. Tumor angiogenesis as a predictor of recurrence in stage Ib squamous cell carcinoma of the cervix. Obstet Gynecol 1996;87:751-4.
20. Guidi AJ, Abu-Jawdeh G, Tognazzi K, Dvorak HF, Brown LF. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in endometrial carcinoma. Cancer 1996;78:454-60.
21. Hollingsworth HC, Kohn EC, Steinberg SM, Rothenberg ML, Merino MJ. Tumor angiogenesis in advanced stage ovarian carcinoma. Am J Pathol 1995;147:33-41.
22. Simpson JF, Ahn C, Battifora H, Esteban JM. Endothelial area as a prognostic indicator for invasive breast carcinoma. Cancer 1996;77:2077-85.
23. Barbareschi M, Weidner N, Gasparini G, Morelli L, Forti ST, Eccher C, et al. Microvessel density quantification in breast carcinomas. Appl Immunohistochem 1995;3(2):75-84.
24. Mason DY, Stein H, Naiem M, Abdulaziz Z. Immunohistological analysis of human lymphoid tissue by double immunoenzymatic labelling. J Cancer Res Clin Oncol 1981;101(1):13-22.
25. Cordell JL, Falini B, Erber WN, Gosh AK, Abdulaziz Z, MacDonald S, et al. Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phsphatase (APAAP complexes). J Histochem Cytochem 1984;32(2):219-29.
26. Hall NR, Fish DE, Hunt N, Goldin RD. Is the relationship between angiogenesis and metastasis in breast cancer real? Surg Oncol 1992;1:223-9.