The safety of inhaled corticosteroid therapy in children

Current Opinion in Pediatrics

Volumn 9, Issue 6, 1997, Pages 585-589

  Kamada, Alan K ^a   Szefler, Stanley J ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID;

ADRENAL FUNCTION; ADRENAL INSUFFICIENCY; BONE; CHILD; CHILD GROWTH; CORTICOSTEROID THERAPY; DRUG EFFICACY; DRUG MONITORING; DRUG POTENCY; DRUG SAFETY; GROWTH RETARDATION; HUMAN; INHALATIONAL DRUG ADMINISTRATION; INHALER; OSTEOPOROSIS; PRIORITY JOURNAL; REVIEW; RISK;

EID: 0031436348     PISSN: 10408703     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008480-199712000-00007     Document Type: Review

References (34)

1. Gerdtham UG, Hertzman P, Jonsson B, Boman G: Impact of inhaled corticosteroids on acute asthma hospitalization in Sweden 1978 to 1991. Med Care 1996, 34:1188-1198.
2. Wennergren G, Kristjansson S, Strannegard IL: Decrease in hospitalization for treatment of childhood asthma with increased use of antiinflammatory treament, despite an increase in prevalence of asthma. J Allergy Clin Immunol 1996, 97:742-748.
3. Donohue JG, Weiss ST, Livingston JM, Goetsch MA, Greineder DK, Platt R: Inhaled steroids and the risk of hospitalization for asthma. JAMA 1997, 277:887-891.
4. Haahtela T: Airway remodelling takes place in asthma - what are the clinical implications? Clin Exp Allergy 1997, 27:351-353.
5. Agertoft L, Pedersen S: Effects of long-term treatment with an inhaled corticosteroid on growth and pulmonary function in asthmatic children. Respir Med 1994, 88:373-381.
6. Expert Panel Report 2: Guidelines for the diagnosis and management of asthma. Bethesda: National Institutes of Health, National Heart, Lung, and Blood Institute; publication no. 97-4051, April 1997. Update of the 1991 National Heart, Lung, and Blood Institute asthma management guidelines. Covers all areas of clinical practice, including diagnosis, treatment, monitoring, and patient education.
7. Kamada AK, Szefler SJ: Glucocorticoids and growth in asthmatic children. Pediatr Allergy Immunol 1995, 6:145-154.
8. Wolthers OD: Long-, intermediate-, and short-term growth studies in asthmatic children treated with inhaled glucocorticosteroids. Eur Respir J 1996, 9:821-827.
9. Karlberg J, Gelander L, Albertsson-Wikland K: Distinctions between short-and long-term human growth studies. Acta Paediatr 1993, 83:631-634.
10. Tinkleman DG, Reed CE, Nelson HS, Offord KP: Aerosol beclomethasone dipropionate compared with theophylline as primary treatment of chronic, mild to moderately severe asthma in children. Pediatr 1993, 92:64-77.
11. Doull IJM, Freezer NJ, Holgate ST: Growth of prepubertal children with mild asthma teated with inhaled beclomethasone dipropionate. Am J Respir Crit Care Med 1995, 151:1715-1719.
12. Allen DB, Mullen M, Mullen B: A meta-analysis of the effect of oral and inhaled corticosteroids on growth. J Allergy Clin Immunol 1994, 93:967-976.
13. Todd G, Dunlop K, McNaboe J, Ryan MF, Carson D, Shields MD: Growth and adrenal suppression in asthmatic children treatment with high-dose fluticasone propionate. Thorax 1996, 348:27-29.
14. Lipworth BJ: New perspectives on inhaled drug delivery and systemic bioactivity. Thorax 1995, 50:105-110.
15. Saha M-T, Laippala, Lenko HL: Growth of asthmatic children is slower during than before treatment with inhaled glucocorticoids. Acta Paediatr 1997, 86:138-142.
16. König P, Hillman L, Cervantes C, Levine C, Maloney C, Douglass B, Johnson L, Allern S: Bone metabolism in children with asthma teated with inhaled beclomethasone dipropionate. J Pediatr 1993, 122:219-226.
17. Martinati LC, Bertoldo F, Gasperi E, Micelli S, Boner AL: Effect on cortical and trabecular bone mass of different anti-inflammatory treatments in preadolescent children with chronic asthma. Am J Respir Crit Care Med 1996, 153:232-236.
18. Baraldi E, Bollini MC, De Marchi A, Zacchello F: Effect of beclomethasone dipropionate on bone mineral content assessed by X-ray densitometry in asthmatic children: a longitudinal evaluation. Eur Respir J 1994, 7:710-714.
19. Kamada AK, Szefler SJ, Martin RJ, Boushey HA, Chinchilli VM, Drazen JM, Fish JE, Israel E, Lazarus SC, Lemanske RF, and the Asthma Clinical Research Network: Issues in the use of inhaled glucocorticoids. Am J Respir Crit Care Med 1996, 153:1739-1748. Detailed summary of critical issues related to inhaled steroid therapy.
20. Wolthers OD, Riis BJ, Pedersen S: Bone turnover in asthmatic children treated with oral prednisolone or inhaled budesonide. Pediatr Pulmonol 1993, 16:341-346.
21. Sorva R, Turpeinen M, Juntunen-Backman K, Karonen S-L, Sorva A: Effects of inhaled budesonide on serum markers of bone metabolism. J Allergy Clin Immunol 1992, 90:808-815.
22. Doull I, Freezer N, Holgate ST: Osteocalcin, growth, and inhaled corticosteroids: a prospective study. Arch Dis Child 1996, 74:497-501.
23. Sorva R, Turpeinen M, Juntunen-Backman K, Haahtela T, Risteli L, Risteli J, Sorva A: Changes in bone markers in children with asthma during inhaled budesonide and nedocromil treatments. Acta Paediatr 1996, 80:1176-1180.
24. Wolthers OD, Hansen M, Juul A, Nielsen HK, Pedersen S: Knemometry, urine cortisol excretion, measures of insulin-like growth factor axis, and collagen turnover in children treated with inhaled glucocorticosteroids. Pediatr Res 1997, 41:44-50.
25. Nicolaizik WH, Marchant JL, Preece, Warner JO: Endocrine and lung function in asthmatic children on inhaled corticosteroids. Am J Respir Crit Care Med 1994, 150:624-628.
26. Goldberg S, Algur N, Levi M, Brukheimer E, Hirsch HJ, Branski D, Kerem E: Adrenal suppression among asthmatic children receiving chronic therapy with inhaled corticosteroid with and without spacer device. Ann Allergy Asthma Immunol 1996, 76:234-238.
27. Hoekstra MO, Grol MH, Bouman K, Stijnen T, Koöter GH, Kauffman HF, Gerritsen J: Fluticasone proplnate in children with moderate asthma. Am J Respir Crit Care Med 1996, 154:1039-1044.
28. Yiallouros PK, Milner AD, Conway E, Honour JW: Adrenal function and high dose inhaled corticosteroids for asthma. Arch Dis Child 1997, 76:405-410.
29. Lemanske RF Jr, Allen DB: The safety of chronic asthma treatments: continuous beta agonist therapy and prolonged inhaled corticosteroids in childhood asthma. In Allergy: Principles and Practice, edn 4 (update no. 15). Edited by Middleton E Jr, Reed CE, Ellis EF, Adkinson NF Jr, Yuninger JW, and Busse WW. St. Louis: Mosby-Year; 1993:1-16.
30. Toogood JH, Markov AE, Baskerville J, Dyson C: Association of ocular cataracts with inhaled and oral steroid therapy during long-term treatment of asthma. J Allergy Clin Immunol 1993, 91:571-579.
31. Simons FER, Persaud MP, Cheang M, Shuckett EP: Absence of posterior subcapsular cataracts in young patients treated with inhaled glucocorticoids. Lancet 1993, 342:776-778.
32. Abuekteish F, Kirkpatrick JNP, Russell G: Posterior subcapsular cataract and inhaled corticosteroid therapy. Thorax 1995, 50:674-676.
33. Cumming RG, Mitchell P, Leeder SR: Use of inhaled corticosteroids and the risk of cataracts. N Engl J Med 1997, 337:8-14.
34. Garbe E, LeLorier J, Boivin J-F, Suissa S: Inhaled and nasal glucocorticoids and the risks of ocular hypertension or open-angle glaucoma. JAMA 1997, 277:722-727.