Effect of gallium nitrate on experimental autoimmune uveitis

Experimental Eye Research

Volumn 65, Issue 6, 1997, Pages 797-801

  Lobanoff, Mark C ^a,b   Kozhich, Alexander T ^a   Mullet, Daniel I ^c   Gerber, Nicholas ^c   Gery, Igal ^a   Chan, Chi Chao ^a   Whitcup, Scott M ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Animal model; Autoimmunity; Choroid; Experimental autoimmune uveitis; Eye; Gallium nitrate; Inflammation; Lymphocyte; Retina; Uveitis

Indexed keywords

CONCANAVALIN A; GALLIUM NITRATE; RETINA S ANTIGEN; TUBERCULIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNITY; CHOROID; CONTROLLED STUDY; DRUG EFFECT; EXPERIMENTAL MODEL; IMMUNIZATION; INFLAMMATION; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA; SUBCUTANEOUS DRUG ADMINISTRATION; UVEITIS;

EID: 0031435274     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1997.0395     Document Type: Article

References (17)

1. Barron, D. C. Haynes, B. W. 1986, Determination of gallium in phosphorus flue dust and other materials by graphite furnace atomic absorption spectrometry. Analyst, 111, 19, 21.
2. Caspi, R. R. Roberge, F. G. McAllister, C. El-Saied, M. Kuwabara, T. Gery, I. Hanna, E. Nussenblatt, R. B. 1986, T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat. J. Immunol. 136, 928, 33.
3. Chan, C. C. Mochizuki, M. Nussenblatt, R. B. Palestine, A. G. McAllister, C. Gery, I. BenEzra, D. 1985, T lymphocyte subsets in experimental autoimmune uveitis. Clin. Immunol. Immunopathol. 35, 103, 10.
4. Dorey, C. Cozette, J. Faure, J. P. 1982, A simple and rapid method for isolation of retinal S-antigen. Ophthalmic Res. 14, 249, 55.
5. Dudley, H. C. Munn, J. I. Henry, K. E. 1952, Studies of the metabolism of Gallium II. J. Pharmacol. Exp. Therapeutics. 106, 129, 34.
6. Engvall, E. 1980, Enzyme immunoassay ELISA and EMIT. 419, 39, Academic Press, New York, U.S.A.
7. Huang, E. H. Gabler, D. M. Krecic, M. E. Gerber, N. Ferguson, R. M. Orosz, C. G. 1994, Differential effects of gallium nitrate on T lymphocyte and endothelial cell activation. Transplantation, 58, 1216.
8. Matkovic, V. Apseloff, G. Shepard, D. R. Gerber, N. 1990, Use of gallium to treat Paget's disease of bone: A pilot study. Lancet, 335, 72, 5.
9. Matkovic, V. Balboa, A. Clinchot, D. Whitacre, C. Zwilling, B. Brown, D. Weisbrode, S. E. Apseloff, G. Gerber, N. 1991, Gallium prevents adjuvant arthritis in rats and interferes with macrophage/T-cell function in the immune response. Curr. Ther. Res. 50, 255, 67.
10. Newman, R. A. Brody, A. R. Krakoff, I. H. 1979, Gallium nitrate (NSC-15200) induced toxicity in the rat, a pharmacologic, histopathologic and microanalytical investigation. Cancer, 44, 1728, 40.
11. Nussenblatt, R. B. Dinning, W. J. Fujikawa, L. S. Chan, C. C. Palestine, A. G. 1985, Local cyclosporine therapy for experimental autoimmune uveitis in the rat. Arch Ophthalmol, 103, 1559, 62.
12. Nussenblatt, R. B. Rodrigues, M. M. Wacker, W. B. Cevario, S. J. Salinas-Carmona, M. C. Gery, I. 1981, Cyclosporin A: inhibition of experimental autoimmune uveitis in Lewis rats. J Clin Invest, 67, 1228, 31.
13. Orosz, C. G. Wakely, E. Bergese, S. D. Van Buskirk, A. M. Ferguson, R. M. Mullet, D. Apseloff, G. Gerber, N. 1996, Prevention of murine cardiac allograft rejection with gallium nitrate. Transplantation, 61, 783, 91.
14. Roberge, F. G. Lorberboum-Galski, H. LeHoang, P. de Smet, M. Chan, C. C. Fitzgerald, D. Pastan, I. 1989, Selective immunosuppression of activated T cells with the chimeric toxin IL-2-PE40. Inhibition of experimental autoimmune uveoretinitis. J Immunol, 143, 3498, 502.
15. Salinas-Carmona, M. C. Nussenblatt, R. B. Gery, I. 1982, Experimental autoimmune uveitis in the athymic nude rat. Eur J Immunol, 25, 481, 4.
16. Wacker, W. B. Donoso, L. A. Kalsow, C. M. Yankelov, J. A. Jr. Organisciak, D. T. 1977, Experimental allergic uveitis: Isolation, characterization, and localization of a soluble uveitopathogenic antigen from bovine retina. J Immunol, 119, 1949, 58.
17. Whitacre, C. Apseloff, G. Cox, K. Matkovic, V. Jewell, S. Gerber, N. 1992, Suppression of experimental autoimmune encephalomyelitis by gallium nitrate. J Neuroimmunol, 39, 175, 82.