-
1
-
-
0027170350
-
Diverse biological activities displayed by phenothiazines, benzo[a]phenothiazines and benz[c]acridins
-
Molnar J, Sakagami H, Motohashi N: Diverse biological activities displayed by phenothiazines, benzo[a]phenothiazines and benz[c]acridins (review). Anticancer Res 13:1019-1026, 1993.
-
(1993)
Anticancer Res
, vol.13
, pp. 1019-1026
-
-
Molnar, J.1
Sakagami, H.2
Motohashi, N.3
-
2
-
-
0026794134
-
Antimicrobial activity of phenothiazines, benzo[a]phenothiazines and benz[c]acridines
-
Motohashi N, Sakagami H, Kurihara T, Ferenzy L. Csuri K, Molnar J: Antimicrobial activity of phenothiazines, benzo[a]phenothiazines and benz[c]acridines. Anticancer Res 12:1207-1210, 1992.
-
(1992)
Anticancer Res
, vol.12
, pp. 1207-1210
-
-
Motohashi, N.1
Sakagami, H.2
Kurihara, T.3
Ferenzy, L.4
Csuri, K.5
Molnar, J.6
-
3
-
-
0026337672
-
Cytotoxicity and differentiation-inducing activity of phenothiazines and benzo[a]phenothiazine derivatives
-
Motohashi N, Sakagami H, Kamata K, Yamamoto Y: Cytotoxicity and differentiation-inducing activity of phenothiazines and benzo[a]phenothiazine derivatives. Anticancer Res 11:1933-1938, 1991.
-
(1991)
Anticancer Res
, vol.11
, pp. 1933-1938
-
-
Motohashi, N.1
Sakagami, H.2
Kamata, K.3
Yamamoto, Y.4
-
4
-
-
0016685584
-
Enhancement of the antitumor effect of l,3-bis(2-chloroethyl)-1-nitrosourea by various psychotropic drugs in combination with caffeine
-
Cohen MH: Enhancement of the antitumor effect of l,3-bis(2-chloroethyl)-1-nitrosourea by various psychotropic drugs in combination with caffeine. J Pharmacol Exp Ther 194:475-479, 1975.
-
(1975)
J Pharmacol Exp Ther
, vol.194
, pp. 475-479
-
-
Cohen, M.H.1
-
5
-
-
0024815621
-
4
-
4. Biochem J 264:527-532, 1989.
-
(1989)
Biochem J
, vol.264
, pp. 527-532
-
-
Poli, G.1
Cheeseman, K.H.2
Biasi, F.3
Chiarpotto, E.4
Dianzani, M.U.5
Esterbauer, H.6
Slater, T.F.7
-
7
-
-
0016232189
-
Induction of cleft palate in mice by tranquilizers and barbiturates
-
Walker BE, Patterson A: Induction of cleft palate in mice by tranquilizers and barbiturates. Teratology 10:159-164, 1974.
-
(1974)
Teratology
, vol.10
, pp. 159-164
-
-
Walker, B.E.1
Patterson, A.2
-
8
-
-
0015949961
-
Species differences in experimental teratogenesis by tranquilizing agents
-
Szabo KT, Brent RL: Species differences in experimental teratogenesis by tranquilizing agents. Lancet 1:565, 1974.
-
(1974)
Lancet
, vol.1
, pp. 565
-
-
Szabo, K.T.1
Brent, R.L.2
-
9
-
-
0016789838
-
Action of the phenothiazine derivative methophenazine on prenatal development in rats
-
Horvath C, Druga A: Action of the phenothiazine derivative methophenazine on prenatal development in rats. Teratology 11:325-330, 1975.
-
(1975)
Teratology
, vol.11
, pp. 325-330
-
-
Horvath, C.1
Druga, A.2
-
10
-
-
0017333442
-
Possible teratogenic effect of phenothiazines in human beings
-
Rumeau-Rouquette C, Goujard J, Huel G: Possible teratogenic effect of phenothiazines in human beings. Teratology 15:57-64, 1977.
-
(1977)
Teratology
, vol.15
, pp. 57-64
-
-
Rumeau-Rouquette, C.1
Goujard, J.2
Huel, G.3
-
11
-
-
0017645155
-
Antenatal exposure to the phenothiazines in relation to congenital malformations, perinatal mortality rate, birth weight and intelligence quotient score
-
Slone D, Siskind V, Heinonen OP, Manson RR, Kaufman DW, Shapiro S: Antenatal exposure to the phenothiazines in relation to congenital malformations, perinatal mortality rate, birth weight and intelligence quotient score. Am J Obstet Gynecol 128:486-488, 1977
-
(1977)
Am J Obstet Gynecol
, vol.128
, pp. 486-488
-
-
Slone, D.1
Siskind, V.2
Heinonen, O.P.3
Manson, R.R.4
Kaufman, D.W.5
Shapiro, S.6
-
12
-
-
0017078335
-
An evaluation of the teratogenicity of certain antinauseant drugs
-
Milkovich L, van den Berg BJ: An evaluation of the teratogenicity of certain antinauseant drugs. Am J Obstet Gynecol 125:244-248. 1976.
-
(1976)
Am J Obstet Gynecol
, vol.125
, pp. 244-248
-
-
Milkovich, L.1
Van Den Berg, B.J.2
-
13
-
-
68749090490
-
Fetal damage due to ECT, insulin coma, chlorpromazine, or reserpine
-
Sobel DE: Fetal damage due to ECT, insulin coma, chlorpromazine, or reserpine. Arch Gen Psychiatry 2:606-611, 1960.
-
(1960)
Arch Gen Psychiatry
, vol.2
, pp. 606-611
-
-
Sobel, D.E.1
-
14
-
-
0015403733
-
Stability of some phenothiazine free radicals
-
Levy L, Tozer TN, Tuck LD, Loveland DB: Stability of some phenothiazine free radicals. J Med Chem 15:898-905, 1972.
-
(1972)
J Med Chem
, vol.15
, pp. 898-905
-
-
Levy, L.1
Tozer, T.N.2
Tuck, L.D.3
Loveland, D.B.4
-
15
-
-
0026008582
-
Oxidation of chlorpromazine by methemoglobin in the presence of hydrogen peroxide. Formation of chlorpromazine radical cation and its covalent binding to methemoglobin
-
Kelder PP, Fischer MJE, De Mol NJ, Janssen LHM: Oxidation of chlorpromazine by methemoglobin in the presence of hydrogen peroxide. Formation of chlorpromazine radical cation and its covalent binding to methemoglobin. Arch Biochem Biophys 284:313-319, 1991.
-
(1991)
Arch Biochem Biophys
, vol.284
, pp. 313-319
-
-
Kelder, P.P.1
Fischer, M.J.E.2
De Mol, N.J.3
Janssen, L.H.M.4
-
16
-
-
0025727063
-
Metabolic activation of chlorpromazine by stimulated human polymorphonuclear leukocytes. Induction of covalent binding of chlorpromazine to nucleic acids and proteins
-
Kelder PP, De Mol NJ, Hart BA, Janssen LHM: Metabolic activation of chlorpromazine by stimulated human polymorphonuclear leukocytes. Induction of covalent binding of chlorpromazine to nucleic acids and proteins. Chem Biol Int 79:15-30, 1991.
-
(1991)
Chem Biol Int
, vol.79
, pp. 15-30
-
-
Kelder, P.P.1
De Mol, N.J.2
Hart, B.A.3
Janssen, L.H.M.4
-
17
-
-
0001138405
-
Electron-paramagnetic resonance studies of the chlorpromazine free radical formed during enzymatic oxidation by peroxidase-hydrogen peroxide
-
Piette LH, Bulow G, Yamazaki J: Electron-paramagnetic resonance studies of the chlorpromazine free radical formed during enzymatic oxidation by peroxidase-hydrogen peroxide. Biochim Biophys Acta 88:120-129, 1964.
-
(1964)
Biochim Biophys Acta
, vol.88
, pp. 120-129
-
-
Piette, L.H.1
Bulow, G.2
Yamazaki, J.3
-
18
-
-
0026632921
-
Determination of the molar absorptivities of phenothiazine cation radicals generated by oxidation with hydrogen peroxide/peroxidase
-
Vazquez A, Tudela J, Varon R, Garcia-Canovas F: Determination of the molar absorptivities of phenothiazine cation radicals generated by oxidation with hydrogen peroxide/peroxidase. Anal Biochem 202:245-248, 1992.
-
(1992)
Anal Biochem
, vol.202
, pp. 245-248
-
-
Vazquez, A.1
Tudela, J.2
Varon, R.3
Garcia-Canovas, F.4
-
19
-
-
0028265965
-
Kinetic evaluation of the oxidation of phenothiazine derivatives by mehemoglobin and horseradish peroxidase in the presence of hydrogen peroxide. Implications for the reaction mechanisms
-
Kelder PP, deMol NJ, Fischer MJE, Janssen HM: Kinetic evaluation of the oxidation of phenothiazine derivatives by mehemoglobin and horseradish peroxidase in the presence of hydrogen peroxide. Implications for the reaction mechanisms. Biochim Biophys Acta 1205:230-238, 1994.
-
(1994)
Biochim Biophys Acta
, vol.1205
, pp. 230-238
-
-
Kelder, P.P.1
DeMol, N.J.2
Fischer, M.J.E.3
Janssen, H.M.4
-
21
-
-
0028001068
-
Lipoxygenase-catalyzed oxidation of chlorpromazine by hydrogen peroxide at acidic pH
-
Perez-Gilabert M, Sanchez-Ferrer A, Garcia-Carmona F: Lipoxygenase-catalyzed oxidation of chlorpromazine by hydrogen peroxide at acidic pH. Biochim Biophys Acta 1214:203-208, 1994.
-
(1994)
Biochim Biophys Acta
, vol.1214
, pp. 203-208
-
-
Perez-Gilabert, M.1
Sanchez-Ferrer, A.2
Garcia-Carmona, F.3
-
22
-
-
0008029432
-
Placental enzymes: Cytochrome P450s and their significance
-
Rama Sastry BV: Boca Raton, FL: CRC Press
-
Juchau MR: Placental enzymes: Cytochrome P450s and their significance. In Rama Sastry BV: "Placental Toxicology." Boca Raton, FL: CRC Press, 1995, pp 197-212.
-
(1995)
Placental Toxicology
, pp. 197-212
-
-
Juchau, M.R.1
-
23
-
-
0001947223
-
Role of xenobiotic metabolism in developmental toxicity
-
Hood RD: Boca Raton, FL: CRC Press
-
Kulkarni AP: Role of xenobiotic metabolism in developmental toxicity. In Hood RD: "Handbook of Developmental Toxicology." Boca Raton, FL: CRC Press, 1996, pp 383-412.
-
(1996)
Handbook of Developmental Toxicology
, pp. 383-412
-
-
Kulkarni, A.P.1
-
24
-
-
0025325298
-
Partial purification and characterization of a peroxidase activity from human placenta
-
Nelson JL, Kulkarni AP: Partial purification and characterization of a peroxidase activity from human placenta. Biochem J 268:739-743, 1990.
-
(1990)
Biochem J
, vol.268
, pp. 739-743
-
-
Nelson, J.L.1
Kulkarni, A.P.2
-
25
-
-
0027096212
-
Peroxidase: A novel pathway for chemical oxidation in human term placenta
-
Joseph P, Murthy KR, Nelson JL, Kulkarni AP: Peroxidase: A novel pathway for chemical oxidation in human term placenta. Placenta 13:545-554, 1992.
-
(1992)
Placenta
, vol.13
, pp. 545-554
-
-
Joseph, P.1
Murthy, K.R.2
Nelson, J.L.3
Kulkarni, A.P.4
-
26
-
-
0027220234
-
Placental peroxidase - Further purification of the enzyme and oxidation of thiobenzamide
-
Joseph P, Srinivan NS, Kulkarni AP: Placental peroxidase - Further purification of the enzyme and oxidation of thiobenzamide. Placenta 14:309-319, 1993.
-
(1993)
Placenta
, vol.14
, pp. 309-319
-
-
Joseph, P.1
Srinivan, N.S.2
Kulkarni, A.P.3
-
27
-
-
0028018492
-
Xenobiotic oxidation during early pregnancy in man: Peroxidase catalyzed chemical oxidation in conceptual tissues
-
Joseph P, Srinivan NS, Kulkarni AP: Xenobiotic oxidation during early pregnancy in man: Peroxidase catalyzed chemical oxidation in conceptual tissues. Xenobiotica 24:583-590, 1994.
-
(1994)
Xenobiotica
, vol.24
, pp. 583-590
-
-
Joseph, P.1
Srinivan, N.S.2
Kulkarni, A.P.3
-
29
-
-
0027202778
-
Purification and partial characterization of lipoxygenase with dual catalytic activities from human term placenta
-
Joseph P, Srinivan NS, Kulkarni AP: Purification and partial characterization of lipoxygenase with dual catalytic activities from human term placenta. Biochem J 293:83-91, 1993.
-
(1993)
Biochem J
, vol.293
, pp. 83-91
-
-
Joseph, P.1
Srinivan, N.S.2
Kulkarni, A.P.3
-
30
-
-
0028593622
-
1 by lipoxygenase purified from human term placenta and intrauterine conceptual tissues
-
1 by lipoxygenase purified from human term placenta and intrauterine conceptual tissues. Teratology 50:311-317, 1994.
-
(1994)
Teratology
, vol.50
, pp. 311-317
-
-
Datta, K.1
Kulkarni, A.P.2
-
31
-
-
0030111313
-
Co-oxidation of t-retinol acetate by human term placental lipoxygenase and soybean lipoxygenase
-
Datta K, Kulkarni AP: Co-oxidation of t-retinol acetate by human term placental lipoxygenase and soybean lipoxygenase. Reprod Toxicol 10:105-112, 1996.
-
(1996)
Reprod Toxicol
, vol.10
, pp. 105-112
-
-
Datta, K.1
Kulkarni, A.P.2
-
32
-
-
0031033643
-
Co-oxidative metabolism of 4-aminobiphenyl by lipoxygenase from soybean and human term placenta
-
Datta K, Sherblom PM, Kulkarni AP: Co-oxidative metabolism of 4-aminobiphenyl by lipoxygenase from soybean and human term placenta. Drug Metab Disp 25:196-205, 1997.
-
(1997)
Drug Metab Disp
, vol.25
, pp. 196-205
-
-
Datta, K.1
Sherblom, P.M.2
Kulkarni, A.P.3
-
33
-
-
0001153840
-
In vitro embryotoxicity of ethylene dibromide bioactivated by purified human term placental glutathione S-transferase
-
Mitra AK, Hilbelink DR, Dwornik JJ, Kulkarni AP: In vitro embryotoxicity of ethylene dibromide bioactivated by purified human term placental glutathione S-transferase. Int J Occup Med Toxicol 2:101-114,1993.
-
(1993)
Int J Occup Med Toxicol
, vol.2
, pp. 101-114
-
-
Mitra, A.K.1
Hilbelink, D.R.2
Dwornik, J.J.3
Kulkarni, A.P.4
-
34
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram protein utilizing the principle of protein-dye binding
-
Bradford MM: A rapid and sensitive method for the quantitation of microgram protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, 1976.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
35
-
-
0016425727
-
Properties of enzymes. III. A comparative study of peroxide decomposing enzymes and superoxide dismutase of human placenta of different ages
-
Matkovics B, Fodor I, Kovacs K: Properties of enzymes. III. A comparative study of peroxide decomposing enzymes and superoxide dismutase of human placenta of different ages. Enzyme 19:285-298, 1975.
-
(1975)
Enzyme
, vol.19
, pp. 285-298
-
-
Matkovics, B.1
Fodor, I.2
Kovacs, K.3
-
36
-
-
0004839842
-
Effects of phenylbutazone and amino acids on benzo(a)pyrene-7,8-dihydrodiol co-oxygenation by partially purified placental peroxidase
-
Kulkarni AP, Joseph P, Byczkowski JZ: Effects of phenylbutazone and amino acids on benzo(a)pyrene-7,8-dihydrodiol co-oxygenation by partially purified placental peroxidase. Toxicologist 12:197, 1992.
-
(1992)
Toxicologist
, vol.12
, pp. 197
-
-
Kulkarni, A.P.1
Joseph, P.2
Byczkowski, J.Z.3
-
37
-
-
0025075737
-
Activation of chlorpromazine by the myeloperoxidase system of the human neutrophil
-
Van Zyl JM, Basson K, Kriegler A, van der Walt B: Activation of chlorpromazine by the myeloperoxidase system of the human neutrophil. Biochem Pharmacol 40:947-954, 1990.
-
(1990)
Biochem Pharmacol
, vol.40
, pp. 947-954
-
-
Van Zyl, J.M.1
Basson, K.2
Kriegler, A.3
Van Der Walt, B.4
-
38
-
-
0018012001
-
Reactions of chlorpromazine cation radical with physiologically occurring nucleophiles
-
Cheng HY, Sackett PH, McCreery RL: Reactions of chlorpromazine cation radical with physiologically occurring nucleophiles. J Med Chem 21:948-952, 1978.
-
(1978)
J Med Chem
, vol.21
, pp. 948-952
-
-
Cheng, H.Y.1
Sackett, P.H.2
McCreery, R.L.3
-
39
-
-
0015927958
-
Thin layer chromatography of chlorpromazine metabolites
-
Turano P, Turner WJ, Manian AA: Thin layer chromatography of chlorpromazine metabolites. J Chromatogr 75:277-293, 1973.
-
(1973)
J Chromatogr
, vol.75
, pp. 277-293
-
-
Turano, P.1
Turner, W.J.2
Manian, A.A.3
-
40
-
-
0017363360
-
Formation of chlorpromazine sulfoxide and monodesmethylchlorpromazine by microsomes of small intestine
-
Knoll R, Crist W, Muller-Oerlinghausen B, Coper H: Formation of chlorpromazine sulfoxide and monodesmethylchlorpromazine by microsomes of small intestine. Naunyn Schmiedebergs Arch Pharmacol 297:195-200, 1977.
-
(1977)
Naunyn Schmiedebergs Arch Pharmacol
, vol.297
, pp. 195-200
-
-
Knoll, R.1
Crist, W.2
Muller-Oerlinghausen, B.3
Coper, H.4
-
41
-
-
0020061769
-
Metabolism of chlorpromazine by pulmonary microsomal enzymes in the rat and rabbit
-
Ohmiya J, Mehendale HM: Metabolism of chlorpromazine by pulmonary microsomal enzymes in the rat and rabbit. Biochem Pharmacol 31:157-162, 1982.
-
(1982)
Biochem Pharmacol
, vol.31
, pp. 157-162
-
-
Ohmiya, J.1
Mehendale, H.M.2
-
42
-
-
0022633430
-
Irreversible binding with biological macromolecules and effects in bacterial mutagenicity tests of the radical cation of promethazine and photoactivated promethazine. Comparison with chlorpromazine
-
De Mol NJ, Becht ABC, Koenen J, Lodder G: Irreversible binding with biological macromolecules and effects in bacterial mutagenicity tests of the radical cation of promethazine and photoactivated promethazine. Comparison with chlorpromazine. Chem Biol Int 57:73-83, 1986.
-
(1986)
Chem Biol Int
, vol.57
, pp. 73-83
-
-
De Mol, N.J.1
Becht, A.B.C.2
Koenen, J.3
Lodder, G.4
-
43
-
-
0021646460
-
Irreversible binding of the chlorpromazine radical cation and of photoactivated chlorpromazine to biological macromolecules
-
De Mol NJ, Busker RW: Irreversible binding of the chlorpromazine radical cation and of photoactivated chlorpromazine to biological macromolecules. Chem Biol Int 52:79-92, 1984.
-
(1984)
Chem Biol Int
, vol.52
, pp. 79-92
-
-
De Mol, N.J.1
Busker, R.W.2
-
44
-
-
0029128157
-
Xenobiotic metabolism in humans during early pregnancy. Peroxidasemediated oxidation and bioactivation of 2-aminofluorene
-
Kulkarni AP, Murthy KR: Xenobiotic metabolism in humans during early pregnancy. Peroxidasemediated oxidation and bioactivation of 2-aminofluorene. Xenobiotica 25:799-810, 1995.
-
(1995)
Xenobiotica
, vol.25
, pp. 799-810
-
-
Kulkarni, A.P.1
Murthy, K.R.2
-
45
-
-
0028869988
-
Peroxidative xenobiotic oxidation by partially purified peroxidase and lipoxygenase from human fetal tissues at 10 weeks of gestation
-
Datta K, Joseph P, Roy S, Srinivasan SN, Kulkarni AP: Peroxidative xenobiotic oxidation by partially purified peroxidase and lipoxygenase from human fetal tissues at 10 weeks of gestation. Gen Pharmacol 26:107-112, 1995.
-
(1995)
Gen Pharmacol
, vol.26
, pp. 107-112
-
-
Datta, K.1
Joseph, P.2
Roy, S.3
Srinivasan, S.N.4
Kulkarni, A.P.5
|