메뉴 건너뛰기




Volumn 36, Issue 11-12, 1997, Pages 1705-1712

Serotonin inhibits epileptiform discharge by activation of 5-HT(1A) receptors in CA1 pyramidal neurons

Author keywords

8 OH DPAT; Bicuculline; Epilepsy model; Fluoxetine; Hippocampus

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; BICUCULLINE; FLUOXETINE; KETANSERIN; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; RECEPTOR SUBTYPE; SEROTONIN; SEROTONIN 1A RECEPTOR;

EID: 0031431193     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00134-2     Document Type: Article
Times cited : (54)

References (33)
  • 1
    • 0025923176 scopus 로고
    • 5-hydroxytryptamine 4-like receptors mediate the slow excitatory response to serotonin in the rat hippocampus
    • Andrade R. and Chaput Y. (1991) 5-Hydroxytryptamine 4-like receptors mediate the slow excitatory response to serotonin in the rat hippocampus. Journal of Pharmacology and Experimental Therapeutics 257: 930-937.
    • (1991) Journal of Pharmacology and Experimental Therapeutics , vol.257 , pp. 930-937
    • Andrade, R.1    Chaput, Y.2
  • 2
    • 0023470549 scopus 로고
    • Pharmacologically distinct action of serotonin on single pyramidal neurons of the rat hippocampus recorded in vitro
    • Andrade R. and Nicoll R. A. (1987) Pharmacologically distinct action of serotonin on single pyramidal neurons of the rat hippocampus recorded in vitro. Journal of Physiology 394: 99-124.
    • (1987) Journal of Physiology , vol.394 , pp. 99-124
    • Andrade, R.1    Nicoll, R.A.2
  • 3
    • 0026610839 scopus 로고
    • Comparison of 5-HT1a-mediated hyper-polarization in CA1 and CA3 hippocampal pyramidal cells
    • Beck S. G., Choi K. C. and List T. J. (1992) Comparison of 5-HT1A-mediated hyper-polarization in CA1 and CA3 hippocampal pyramidal cells. Journal of Pharmacology and Experimental Therapeutics 263: 350-359.
    • (1992) Journal of Pharmacology and Experimental Therapeutics , vol.263 , pp. 350-359
    • Beck, S.G.1    Choi, K.C.2    List, T.J.3
  • 4
    • 0027283707 scopus 로고
    • NMDA receptors at excitatory synapses in the hippocampus: Test of a theory of magnesium block
    • Bekkers J. M. and Stevens C. F. (1993) NMDA receptors at excitatory synapses in the hippocampus: test of a theory of magnesium block. Neuroscience Letters 156: 73-77.
    • (1993) Neuroscience Letters , vol.156 , pp. 73-77
    • Bekkers, J.M.1    Stevens, C.F.2
  • 5
    • 0025354781 scopus 로고
    • Differential effect of gepirone on presynaptic and postsynaptic serotonin receptors: Single cell recording studies
    • Blier P. and DeMontigny C. (1990) Differential effect of gepirone on presynaptic and postsynaptic serotonin receptors: single cell recording studies. Journal of Clinical Psychopharmacology 10 (Suppl. 3): 13S-20S.
    • (1990) Journal of Clinical Psychopharmacology , vol.10 , Issue.SUPPL. 3
    • Blier, P.1    DeMontigny, C.2
  • 7
    • 0023250760 scopus 로고
    • Differential modulation of three separate K-conductances in hippocampal CA1 neurons by serotonin
    • Colino A. and Halliwell J. V. (1987) Differential modulation of three separate K-conductances in hippocampal CA1 neurons by serotonin. Nature 328: 73-77.
    • (1987) Nature , vol.328 , pp. 73-77
    • Colino, A.1    Halliwell, J.V.2
  • 8
    • 0026608645 scopus 로고
    • Effects of fluoxetine on convulsions and on brain serotonin as detected by microdialysis in genetically epilepsy-prone rats
    • Dailey J. W., Yan Q. S., Mishra P. K., Burger R. C. and Jobe P. C. (1992b) Effects of fluoxetine on convulsions and on brain serotonin as detected by microdialysis in genetically epilepsy-prone rats. Journal of Pharmacology and Experimental Therapeutics 260: 533-540.
    • (1992) Journal of Pharmacology and Experimental Therapeutics , vol.260 , pp. 533-540
    • Dailey, J.W.1    Yan, Q.S.2    Mishra, P.K.3    Burger, R.C.4    Jobe, P.C.5
  • 9
    • 13344279390 scopus 로고
    • Neurochemical correlates of antiepileptic drugs in the genetically epilepsy-prone rat (GEPR)
    • Dailey J. W., Yan Q. S., Adams-Curtis L. E., Ryu J. R., Ko K. H., Mishra P. K. and Jobe P. C. (1995) Neurochemical correlates of antiepileptic drugs in the genetically epilepsy-prone rat (GEPR). Life Science 58: 259-266.
    • (1995) Life Science , vol.58 , pp. 259-266
    • Dailey, J.W.1    Yan, Q.S.2    Adams-Curtis, L.E.3    Ryu, J.R.4    Ko, K.H.5    Mishra, P.K.6    Jobe, P.C.7
  • 10
    • 0025937604 scopus 로고
    • Extracellular magnesium concentration alters Purkinje cell responsiveness to serotonin and analogues
    • Darrow E., Strahlendorf J. C. and Strahlendorf H. K. (1991) Extracellular magnesium concentration alters Purkinje cell responsiveness to serotonin and analogues. European Journal of Pharmacology 209: 19-25.
    • (1991) European Journal of Pharmacology , vol.209 , pp. 19-25
    • Darrow, E.1    Strahlendorf, J.C.2    Strahlendorf, H.K.3
  • 11
    • 0002539701 scopus 로고
    • Electrophysiological evidence for the distinct properties of presynaptic and postsynaptic 5-HT1A receptors: Possible clinical relevance
    • Langer S. Z., Brunello N., Racagni G. and Mendlewicz G., Journal of the International Academy of Biomedical Drug Research, Karger, Basel, Switzerland
    • De Montigny C. and Blier P. (1992) Electrophysiological evidence for the distinct properties of presynaptic and postsynaptic 5-HT1A receptors: possible clinical relevance. In: Serotonin Receptor Subtypes: Pharmacological Significance and Clinical Implications (Langer S. Z., Brunello N., Racagni G. and Mendlewicz G.), Journal of the International Academy of Biomedical Drug Research, Vol. 1, pp. 80-88. Karger, Basel, Switzerland.
    • (1992) Serotonin Receptor Subtypes: Pharmacological Significance and Clinical Implications , vol.1 , pp. 80-88
    • De Montigny, C.1    Blier, P.2
  • 13
    • 0021086972 scopus 로고
    • Identification of presynaptic serotonin autoreceptors using a new ligand: 3H-PAT
    • Gozlan H., El Mestikawy S., Pichat L., Glowinski J. and Hamon M. (1983) Identification of presynaptic serotonin autoreceptors using a new ligand: 3H-PAT. Nature 305: 140-143.
    • (1983) Nature , vol.305 , pp. 140-143
    • Gozlan, H.1    El Mestikawy, S.2    Pichat, L.3    Glowinski, J.4    Hamon, M.5
  • 14
    • 0021971498 scopus 로고
    • Intracellular demonstration of an N-methyl-D-aspartate receptor mediated component of synaptic transmission in the rat hippocampus
    • Herron C. G., Lester R. A. J., Coan E. J. and Collingridge A. L. (1985) Intracellular demonstration of an N-methyl-D-aspartate receptor mediated component of synaptic transmission in the rat hippocampus. Neuroscience Letters 60: 19-23.
    • (1985) Neuroscience Letters , vol.60 , pp. 19-23
    • Herron, C.G.1    Lester, R.A.J.2    Coan, E.J.3    Collingridge, A.L.4
  • 16
    • 0001503815 scopus 로고
    • 5-HT2 receptor blockade to study serotonin-induced pathology
    • Janssen P. A. J. (1983) 5-HT2 receptor blockade to study serotonin-induced pathology. Trends in Pharmacological Sciences 4: 198-206.
    • (1983) Trends in Pharmacological Sciences , vol.4 , pp. 198-206
    • Janssen, P.A.J.1
  • 18
    • 0022372083 scopus 로고
    • Evaluation of the 5-hydroxytryptamine receptor agonist 8-hydroxy-2-(di-n-propylamine) tetralin in different rodent models of epilepsy
    • Loscher W. and Czuczwar S. J. (1985) Evaluation of the 5-hydroxytryptamine receptor agonist 8-hydroxy-2-(di-n-propylamine) tetralin in different rodent models of epilepsy. Neuroscience Letters 60: 201-206.
    • (1985) Neuroscience Letters , vol.60 , pp. 201-206
    • Loscher, W.1    Czuczwar, S.J.2
  • 19
    • 0023149047 scopus 로고
    • Low extracellular magnesium induces epileptiform activity and spreading depression in rat hippocampal slices
    • Mody I., Lambert J. D. C. and Heinemann U. (1987) Low extracellular magnesium induces epileptiform activity and spreading depression in rat hippocampal slices. Journal of Neurophysiology 57: 869-888.
    • (1987) Journal of Neurophysiology , vol.57 , pp. 869-888
    • Mody, I.1    Lambert, J.D.C.2    Heinemann, U.3
  • 20
    • 0028174188 scopus 로고
    • 5-HT1A receptor linked to inward-rectifying potassium current in hippocampal CA3 pyramidal cells
    • Okuhara D. Y. and Beck S. G. (1994) 5-HT1A receptor linked to inward-rectifying potassium current in hippocampal CA3 pyramidal cells. Journal of Neurophysiology 71: 2161-2167.
    • (1994) Journal of Neurophysiology , vol.71 , pp. 2161-2167
    • Okuhara, D.Y.1    Beck, S.G.2
  • 21
    • 0022346190 scopus 로고
    • Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-I receptors
    • Pazos A. and Palacios J. M. (1985) Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-I receptors. Brain Research 346: 205-230.
    • (1985) Brain Research , vol.346 , pp. 205-230
    • Pazos, A.1    Palacios, J.M.2
  • 22
    • 0026670376 scopus 로고
    • Anticonvulsant effect of intranigral fluoxetine
    • Pasini A., Tortorella A. and Gale K. (1992) Anticonvulsant effect of intranigral fluoxetine. Brain Research 593: 287-290.
    • (1992) Brain Research , vol.593 , pp. 287-290
    • Pasini, A.1    Tortorella, A.2    Gale, K.3
  • 23
    • 0029941786 scopus 로고    scopus 로고
    • The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin
    • Pasini A., Tortorella A. and Gale K. (1996) The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin. Brain Research 724: 84-88.
    • (1996) Brain Research , vol.724 , pp. 84-88
    • Pasini, A.1    Tortorella, A.2    Gale, K.3
  • 24
    • 0028889117 scopus 로고
    • Inhibition of epileptiform activity by serotonin in rat CA1 neurons
    • Salgado D. and Alkadhi K. A. (1995) Inhibition of epileptiform activity by serotonin in rat CA1 neurons. Brain Research 669: 176-182.
    • (1995) Brain Research , vol.669 , pp. 176-182
    • Salgado, D.1    Alkadhi, K.A.2
  • 25
    • 0030463937 scopus 로고    scopus 로고
    • Effects of serotonin on induced epileptiform activity in CA1 pyramidal neurons of genetically epilepsy prone rats
    • Salgado-Commissariat D. and Alkadhi K. A. (1996) Effects of serotonin on induced epileptiform activity in CA1 pyramidal neurons of genetically epilepsy prone rats. Brain Research 743: 212-216.
    • (1996) Brain Research , vol.743 , pp. 212-216
    • Salgado-Commissariat, D.1    Alkadhi, K.A.2
  • 26
    • 0022604794 scopus 로고
    • Hippocampal slices in experimental and human epilepsy
    • Degado-Escueta A. V., Ward A. A. Jr, Woodbury D. M. and Porter R. J., Raven Press, New York
    • Schwartzkroin P. A. (1986) Hippocampal slices in experimental and Human epilepsy. In: Advances in Neurology (Degado-Escueta A. V., Ward A. A. Jr, Woodbury D. M. and Porter R. J.), Vol.44, pp. 991-1010. Raven Press, New York.
    • (1986) Advances in Neurology , vol.44 , pp. 991-1010
    • Schwartzkroin, P.A.1
  • 27
    • 0022404696 scopus 로고
    • Combined inhibition of serotonin uptake and oxidative deamination attenuates audiogenic seizures in DBA/2J mice
    • Sparks D. L. and Buckholtz N. S. (1985) Combined inhibition of serotonin uptake and oxidative deamination attenuates audiogenic seizures in DBA/2J mice. Pharmacology Biochemistry and Behaviour 23: 753-757.
    • (1985) Pharmacology Biochemistry and Behaviour , vol.23 , pp. 753-757
    • Sparks, D.L.1    Buckholtz, N.S.2
  • 28
    • 0026521922 scopus 로고
    • Behavioral and electroencephalographic effects of aserotonin receptor agonist (5-methoxy-N,N-dimethyltryptamine) in a feline model of photosensitive epilepsy
    • Wada Y., Hasegawa H., Nakamura M. and Yamaguchi N. (1992) Behavioral and electroencephalographic effects of aserotonin receptor agonist (5-methoxy-N,N-dimethyltryptamine) in a feline model of photosensitive epilepsy. Neuro-science Letters 138: 115-118.
    • (1992) Neuro-Science Letters , vol.138 , pp. 115-118
    • Wada, Y.1    Hasegawa, H.2    Nakamura, M.3    Yamaguchi, N.4
  • 29
    • 0028946914 scopus 로고
    • Prolonged but not acute fluoxetine administration produces its inhibitory effect on hippocampal seizures in rats
    • Wada Y., Shiraishi J., Nakamura M. and Hasegawa H. (1995) Prolonged but not acute fluoxetine administration produces its inhibitory effect on hippocampal seizures in rats. Psychopharmacology (Berlin) 118: 305-309.
    • (1995) Psychopharmacology (Berlin) , vol.118 , pp. 305-309
    • Wada, Y.1    Shiraishi, J.2    Nakamura, M.3    Hasegawa, H.4
  • 30
    • 0027957693 scopus 로고
    • Evidence that a serotonergic mechanism is involved in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats
    • Yan Q.-S., Jobe P. C. and Dailey J. W. (1994a) Evidence that a serotonergic mechanism is involved in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats. European Journal of Pharmacology 252: 105-122.
    • (1994) European Journal of Pharmacology , vol.252 , pp. 105-122
    • Yan, Q.-S.1    Jobe, P.C.2    Dailey, J.W.3
  • 32
    • 0029127983 scopus 로고
    • Further evidence of anticonvulsant role for 5-hyroxytryptamine in genetically epilepsy-prone rats
    • Yan Q.-S., Jobe P. C. and Dailey J. W. (1995) Further evidence of anticonvulsant role for 5-hyroxytryptamine in genetically epilepsy-prone rats. British Journal of Pharmacology 115: 1314-1318.
    • (1995) British Journal of Pharmacology , vol.115 , pp. 1314-1318
    • Yan, Q.-S.1    Jobe, P.C.2    Dailey, J.W.3
  • 33
    • 0026761109 scopus 로고
    • 5-hydroxytryptamine receptors
    • Zifa E. and Fillion G. (1992) 5-Hydroxytryptamine receptors. Pharmacological Review 44: 401-457.
    • (1992) Pharmacological Review , vol.44 , pp. 401-457
    • Zifa, E.1    Fillion, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.